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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.615520741401]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
FUS3
  • nucleus
  • cytoplasm
  • mitochondrion
  • mating projection tip
    		•
  • cell cycle arrest
  • invasive growth in response to glucose limitation
  • signal transduction during filamentous growth
  • protein amino acid phosphorylation
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion
    		•
  • MAP kinase activity
    		•
    STE20
  • incipient cellular bud site
  • mating projection tip
    		•
  • cellular bud site selection
  • regulation of exit from mitosis
  • pseudohyphal growth
  • invasive growth in response to glucose limitation
  • protein amino acid phosphorylation
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion
    		•
  • protein serine/threonine kinase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mating projection tip 3.0063E-5 2 35 2 6292
    cell projection part 4.3504E-5 2 42 2 6292
    cell projection 5.9419E-5 2 49 2 6292
    mating projection 5.9419E-5 2 49 2 6292
    site of polarized growth 7.0879E-4 2 168 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    regulation of conjugation with cellular fusion by signal transduction 1.7735E-5 2 27 2 6292
    pheromone-dependent signal transduction involved in conjugation with cellular fusion 1.7735E-5 2 27 2 6292
    G-protein coupled receptor protein signaling pathway 2.3495E-5 2 31 2 6292
    regulation of multi-organism process 2.5061E-5 2 32 2 6292
    regulation of conjugation 2.5061E-5 2 32 2 6292
    regulation of conjugation with cellular fusion 2.5061E-5 2 32 2 6292
    cell surface receptor linked signaling pathway 2.5061E-5 2 32 2 6292
    invasive growth in response to glucose limitation 5.4619E-5 2 47 2 6292
    response to pheromone involved in conjugation with cellular fusion 1.44E-4 2 76 2 6292
    filamentous growth of a population of unicellular organisms 2.0236E-4 2 90 2 6292
    growth of unicellular organism as a thread of attached cells 2.0236E-4 2 90 2 6292
    response to pheromone 2.3525E-4 2 97 2 6292
    protein amino acid phosphorylation 2.6542E-4 2 103 2 6292
    filamentous growth 2.8118E-4 2 106 2 6292
    cellular response to chemical stimulus 2.8654E-4 2 107 2 6292
    conjugation with cellular fusion 3.9158E-4 2 125 2 6292
    conjugation 3.979E-4 2 126 2 6292
    response to organic substance 4.7071E-4 2 137 2 6292
    multi-organism process 5.13E-4 2 143 2 6292
    growth 5.275E-4 2 145 2 6292
    phosphorylation 8.0494E-4 2 179 2 6292
    signaling pathway 8.5067E-4 2 184 2 6292
    reproductive cellular process 1.1194E-3 2 211 2 6292
    reproductive process 1.1301E-3 2 212 2 6292
    signal transduction 1.1516E-3 2 214 2 6292
    signal transmission 1.1841E-3 2 217 2 6292
    signaling process 1.1841E-3 2 217 2 6292
    phosphorus metabolic process 1.3191E-3 2 229 2 6292
    phosphate metabolic process 1.3191E-3 2 229 2 6292
    sexual reproduction 1.3656E-3 2 233 2 6292
    signaling 1.598E-3 2 252 2 6292
    signal transduction during filamentous growth 2.5415E-3 2 8 1 6292
    reproduction 2.7096E-3 2 328 2 6292
    post-translational protein modification 3.2108E-3 2 357 2 6292
    cell cycle arrest 3.4937E-3 2 11 1 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    response to chemical stimulus 3.6769E-3 2 382 2 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    protein modification process 6.278E-3 2 499 2 6292
    cell cycle 6.95E-3 2 525 2 6292
    regulation of exit from mitosis 7.9314E-3 2 25 1 6292
    exit from mitosis 7.9314E-3 2 25 1 6292
    macromolecule modification 8.1649E-3 2 569 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein serine/threonine kinase activity 2.0691E-4 2 91 2 6292
    protein kinase activity 6.1087E-4 2 156 2 6292
    phosphotransferase activity, alcohol group as acceptor 9.8542E-4 2 198 2 6292
    kinase activity 1.2395E-3 2 222 2 6292
    MAP kinase activity 1.5888E-3 2 5 1 6292
    transferase activity, transferring phosphorus-containing groups 4.4459E-3 2 420 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle