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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.664463664989]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SNF7
  • ESCRT III complex
  • cytoplasm
    		•
  • ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
  • late endosome to vacuole transport
  • telomere maintenance
    		•
  • protein binding
    		•
    SRN2
  • endosome
  • ESCRT I complex
    		•
  • ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
  • protein targeting to membrane
  • protein targeting to vacuole
    		•
  • protein binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    endosomal part 1.2783E-5 2 23 2 6292
    endosome membrane 1.2783E-5 2 23 2 6292
    endosome 2.2085E-4 2 94 2 6292
    ESCRT III complex 1.5888E-3 2 5 1 6292
    ESCRT I complex 1.9064E-3 2 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 7.7306E-6 2 18 2 6292
    vacuolar transport 3.312E-4 2 115 2 6292
    modification-dependent protein catabolic process 6.1087E-4 2 156 2 6292
    ubiquitin-dependent protein catabolic process 6.1087E-4 2 156 2 6292
    proteolysis involved in cellular protein catabolic process 6.3467E-4 2 159 2 6292
    modification-dependent macromolecule catabolic process 6.7534E-4 2 164 2 6292
    cellular protein catabolic process 7.3441E-4 2 171 2 6292
    proteolysis 8.8816E-4 2 188 2 6292
    protein catabolic process 8.9766E-4 2 189 2 6292
    cellular macromolecule catabolic process 1.7674E-3 2 265 2 6292
    macromolecule catabolic process 2.1762E-3 2 294 2 6292
    cellular catabolic process 4.3405E-3 2 415 2 6292
    catabolic process 6.2027E-3 2 496 2 6292
    late endosome to vacuole transport 7.6148E-3 2 24 1 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle