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Protein Overview: FET3

General Information:
Name(s) found: FET3 / YMR058W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 636 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDALink to PubMed articleLink to PubMed article]
    Biological Process: high-affinity iron ion transport [IDALink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    response to copper ion [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: iron ion transmembrane transporter activity [IDALink to PubMed article]
    ferroxidase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNALLSIAV LLFSMLSLAQ AETHTFNWTT GWDYRNVDGL KSRPVITCNG QFPWPDITVN  60
   61 KGDRVQIYLT NGMNNTNTSM HFHGLFQNGT ASMDGVPFLT QCPIAPGSTM LYNFTVDYNV 120
  121 GTYWYHSHTD GQYEDGMKGL FIIKDDSFPY DYDEELSLSL SEWYHDLVTD LTKSFMSVYN 180
  181 PTGAEPIPQN LIVNNTMNLT WEVQPDTTYL LRIVNVGGFV SQYFWIEDHE MTVVEIDGIT 240
  241 TEKNVTDMLY ITVAQRYTVL VHTKNDTDKN FAIMQKFDDT MLDVIPSDLQ LNATSYMVYN 300
  301 KTAALPTQNY VDSIDNFLDD FYLQPYEKEA IYGEPDHVIT VDVVMDNLKN GVNYAFFNNI 360
  361 TYTAPKVPTL MTVLSSGDQA NNSEIYGSNT HTFILEKDEI VEIVLNNQDT GTHPFHLHGH 420
  421 AFQTIQRDRT YDDALGEVPH SFDPDNHPAF PEYPMRRDTL YVRPQSNFVI RFKADNPGVW 480
  481 FFHCHIEWHL LQGLGLVLVE DPFGIQDAHS QQLSENHLEV CQSCSVATEG NAAANTLDLT 540
  541 DLTGENVQHA FIPTGFTKKG IIAMTFSCFA GILGIITIAI YGMMDMEDAT EKVIRDLHVD 600
  601 PEVLLNEVDE NEERQVNEDR HSTEKHQFLT KAKRFF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) AHA1 ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 ATG12 ATG5 ATP3 CLU1 CRM1 CYS3 ERG20 FAA4 FET3 GCD1 GCD11 GCD2 GCD6 GCD7 GCN3 GFA1 HYM1 IDH1 KAP122 KGD1 LOS1 MET10 MET18 NMD5 NTG1 PEX19 PFK1 PRB1 PRO3 PST2 PUF3 RFC2 RPC40 RPN1 RPN8 RVB1 SCW4 SUI3 TIF34 UFD4 VAC8 VMA8
    View Details Qiu et al. (2008) ARN2 ENB1 FET3 FET4 FRE1 FRE2 FRE3 FRE4 FTH1 FTR1 ZRT1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data FET3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..320]
    [514..545]    		 PSI-BLAST 627.228787 Laccase
    2 View Details [321..513] PSI-BLAST 627.228787 Laccase
    3 View Details [546..636] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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