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Protein Overview: ARC15

General Information:
Name(s) found: ARC15 / YIL062C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 154 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial envelope [TASLink to PubMed article]
    Arp2/3 protein complex [IDALink to PubMed articleLink to PubMed article]
    Biological Process: mitochondrion inheritance [IMPLink to PubMed article][IPILink to PubMed article]
    actin cortical patch assembly [IMPLink to PubMed article]
    Molecular Function: actin binding [TASLink to PubMed article]
    structural molecule activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEADWRRIDI DAFDPESGRL TAADLVPPYE TTVTLQELQP RMNQLRSLAT SGDSLGAVQL  60
   61 LTTDPPYSAD APTKEQYFKS VLEALTQVRQ ADIGNVIKNL SDSQRDVLVK YLYKGMSVPQ 120
  121 GQKQGGVLLA WLERITQVSG VTPIVHYISD RRTV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3
    View Details (MIPS) Mewes HW, et al. (2004) ARC15 ARC18 ARC19 ARC35 ARP2 ARP3
    View Details Krogan NJ, et al. (2006) ARC15 ASR1 CAJ1 CDC7 CRN1 INP52 IRC22 MSK1 PNO1 PST2 RAD34 SAC6 SAR1 SLM1 TCP1 TED1 YPP1
    View Details Gavin AC, et al. (2006) ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3
    View Details Gavin AC, et al. (2002) ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 CCT5 CCT8 NOG2 PFK1 PRT1
    View Details Ho Y, et al. (2002) ADR1 ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 ATP3 BNI1 DUR1,2 FET3 GFA1 IMH1 KAP122 MCM4 MCM7 MET18 PST2 PUF3 RPN8 RPT4 RVB1 TRP3 YJR029W
    View Details Qiu et al. (2008) ARC15 ARC18 ARC19 ARC35 ARP2 ARP3 ENT1 PFY1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ARC15 and SAC6 Huh WK, et al. (2003)
    View Data ARC15 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..80] PSI-BLAST 128.9897 Arp2/3 complex 16 kDa subunit ARPC5
    2 View Details [81..154] PSI-BLAST 128.9897 Arp2/3 complex 16 kDa subunit ARPC5

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  4.05206194993572 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.8232927372914 bayes_pls_golite062009
  • binding
    		•  2.61919369153094 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  1.81816151576197 bayes_pls_golite062009
  • structural molecule activity
    		•  1.11205059538724 bayes_pls_golite062009
  • protein binding
    		•  0.604512822275397 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle