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Protein Overview: STB4

General Information:
Name(s) found: STB4 / YMR019W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Protein that binds Sin3p in a two-hybrid assay; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins; computational analysis suggests a role in regulation of expression of genes encoding transporters [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 949 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article][ISSLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: DNA binding [IPILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSINHEIYYI LVFEHRSVAI KLIIVVIVLL QFFLARSRQI DRTWAHTNRK ERFREMTAIG  60
   61 NTDDALDTST AASKENGKGR LRVQKACELC KKRKVKCDGN NPCLNCSKHQ KECRYDFKAT 120
  121 NRKRRRRQVA SAVRDVSKTY AETSESFPRD LLSKSNIIIN APSDGVSSSA SNSPNPNSHY 180
  181 HHISSTLPFM SGRPNHTFHS GSNLNGENNN NSFPEDHMAK LLLQLSSKLG NTTKESSIRT 240
  241 TRTNASDVNA NPTVVNMKNS QEDCDTNHRS AICDSAEALH NNNINSKENK IINSQITNTV 300
  301 NDHFESPWQT FSLDKYRFHR RYQNILPYYL GVSILKDLSP QTIEYAKLKR PRVQNYGWNL 360
  361 SGGHYLKYKG DFRSQEKNIR HESKFFDFDD PVHLSLINKL LRYYFDEINP VFSIIHEATF 420
  421 WQQYNNKFLR QGKQNNSSAN LFTSMLYLIL STTLRFREGH LDGQKGQGTY SNTSLNITFE 480
  481 EKSILIKKPS IEENLFKYAY LIINTLTFEW ESFELIQSWL LITFYFRTCY RQTACWNALS 540
  541 QAVNMCNGMS LYLNKFPEIH STYDESKAWH CFWCCFIMDK LISFQMGRFY QLSLPASEMC 600
  601 EQMNLVKSKK FLQEEDDWFH EETFQMLDLS IIVTQFLKRD AQDLNLNETV QLRSQLGQWY 660
  661 DTFIVGSQTN AYDDNYRYFY QVQPFMTYLD IRLTFEVRQL FCLIAPSSTA NNKSLEYVVD 720
  721 TELLISHCQM AIENLAEITR SNLFFVPWWL NLSQLFTVNL ICIIYLHAGI AVTQNKAIMQ 780
  781 SCQEIWRTLE CSKPKNRPSM LPECLWCLKM LNHMFCIRLR DSALQLEATL GTDHGDDTPN 840
  841 RNKFEQFKKV GDNDADVEVD AGEREENADE RQENPHNNSK RVPLATRSHN TTNFDGSIAI 900
  901 SPESAVANLG TDTGLPSDVL DTVSKIGNSP NVFDDDLFSN LLWFDQNFA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BIK1 ERG29 PKH3 RTR1 STB4
    View Details Ho Y, et al. (2002) ARP4 FAA2 HFI1 RPO31 SPT7 STB4 SWC4 SWI5 TRA1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data STB4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..67] deduced N/A No confident structure predictions are available.
    2 View Details [68..222] PSI-BLAST 13.522879 PPR1
    3 View Details [223..949] deduced N/A No confident structure predictions are available.
    4 View Details [245..369] FFAS03 2.25 PPR1
    5 View Details [370..460] deduced N/A No confident structure predictions are available.
    6 View Details [461..669] deduced N/A No confident structure predictions are available.
    7 View Details [670..837] deduced N/A No confident structure predictions are available.
    8 View Details [838..949] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • nucleic acid binding
    		•  1.82012686871762 bayes_pls_golite062009
  • DNA binding
    		•  1.78629392205727 bayes_pls_golite062009
  • binding
    		•  1.76935935681721 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.70162817919532 bayes_pls_golite062009
  • transcription factor activity
    		•  0.606922041618269 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.160255273911114 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0882387940255902 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.67816066599632 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.62620944167363 bayes_pls_golite062009
  • DNA binding
    		•  1.56468711383438 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.48580372603095 bayes_pls_golite062009
  • transcription factor activity
    		•  0.430971106781157 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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