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Protein Overview: MCX1

General Information:
Name(s) found: MCX1 / YBR227C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Mitochondrial matrix protein; putative ATP-binding chaperone with non-proteolytic function; similar to bacterial ClpX proteins [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 520 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: ATP binding [ISSLink to PubMed article]
    unfolded protein binding [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKSASQNFF RAYSSRIGRY AATASGKLAQ SRLSNIPTPK ALKKFLDEYI VGQEIGKKVL  60
   61 SVAVYNHYLR INDKQKKGEL QRQRELMERE KIADDRDEPI FSGNSESKAG WRNLQRQFNL 120
  121 AGREVDEDLE LSKSNVLVVG PSGSGKTLLA TTLAKILNVP IAITDCTQLT QAGYIGEDVE 180
  181 VCIERLLVNA EFDVARAEKG IIVLDEIDKL AKPAASIGTK DVSGEGVQQS LLKIIEGHKV 240
  241 EITVKRPVKH DIDGQKNQTT TKKDEVFVVD TSNILFMIMG AFVGLDKHIV KRIEDMKKIQ 300
  301 KAGESVESSN SKEVEKERAK KFRFSNTLEQ VELDNGKKVC ALDLTTPTDL VSFGLIPELI 360
  361 GRVPIITALQ PLQRDDLFHI LKEPKNALLD QYEYIFKQFG VRLCVTQKAL KKVAQFALKE 420
  421 GTGARGLRGI MERLLLNVNY DCPGSNIAYV LIDEATVDSL QETEHSLASQ VDVKYYSGDE 480
  481 KDSLIRDVSE EDKKLGVMLE KELGHSANIH TPTIPKRSLT

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) BGL2 CBP6 CDC15 DUG2 FRS2 GCD11 GCN3 HXT7 MCX1 NDE1 NMD3 NPA3 PET10 PET9 PST2 SAR1 SLC1 TEM1 TRP3 TRP5 VPS8 YHR033W YNK1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run BOI2 Boi 2 gst control McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data MCX1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..520] PSI-BLAST 259.9897 HslU

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  2.55157966585974 bayes_pls_golite062009
  • binding
    		•  1.62320027057768 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.569910969126728 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.568840867400671 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.568779924702229 bayes_pls_golite062009
  • nucleotide binding
    		•  0.564275755355315 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.546796591575762 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.543610140926125 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.540750418412449 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.517457589081898 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.318452816722389 bayes_pls_golite062009
  • ATP binding
    		•  0.1860481660648 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.152859582615242 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.138615225841109 bayes_pls_golite062009
  • helicase activity
    		•  0.0450969969658499 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle