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Bait Protein: ASF1
Organism: Saccharomyces cerevisiae
Publication: Green EM, Antczak AJ, Bailey AO, Franco AA, Wu KJ, Yates JR 3rd, Kaufman PD. Replication-independent histone deposition by the HIR complex and Asf1. Curr Biol. 2005 Nov 22;15(22):2044-9.
Comments: 3829 - low filter

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  Hit Protein Protein Desc Sequence Count Spectrum Count Sequence Coverage NSAF Mol. Wt.
[View Peptides]   ASF1 Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein t... 22 77 53.4% 0.501 31603
[View Peptides]   ORC6 Subunit of the origin recognition complex, which directs DNA replication by binding to replication o... 2 2 13.8% 0.00835 50296
[View Peptides]   OGG1 Mitochondrial glycosylase/lyase that specifically excises 7,8-dihydro-8-oxoguanine residues located ... 2 2 13.3% 0.00966 42781
[View Peptides]   RAD53 Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autopho... 7 11 12.5% 0.0243 91962
[View Peptides]   ADE12 Adenylosuccinate synthase, catalyzes the first step in synthesis of adenosine monophosphate from ino... 2 2 11.3% 0.00838 48279
[View Peptides]   MBR1 Protein involved in mitochondrial functions and stress response; overexpression suppresses growth de... 3 3 10.9% 0.0161 36935
[View Peptides]   PAP1 Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotei... 2 2 10.4% 0.00639 64552
[View Peptides]   SIR2 Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespa... 2 2 9.4% 0.00646 63262
[View Peptides]   SAT4 Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium t... 2 2 9.0% 0.00602 66666
[View Peptides]   YNL194C Integral membrane protein required for sporulation and plasma membrane sphingolipid content; has seq... 2 2 8.3% 0.0121 34081
[View Peptides]   ENT2 Epsin-like protein required for endocytosis and actin patch assembly and functionally redundant with... 2 2 7.8% 0.00592 71807
[View Peptides]   MNN1 Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for add... 2 2 7.6% 0.00476 88529
[View Peptides]   YBR071W Putative protein of unknown function; (GFP)-fusion and epitope-tagged proteins localize to the cytop... 2 2 7.6% 0.0172 23548
[View Peptides]   YMR031C Protein of unknown function with similarity to Ykl050cp and Uso1p; the authentic, non-tagged protein... 2 2 7.5% 0.00431 93345
[View Peptides]   GUS1 Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; ... 2 2 7.3% 0.00513 80843
[View Peptides]   RAD7 Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleo... 2 2 7.1% 0.00643 63778
[View Peptides]   BPL1 Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for ace... 2 2 6.8% 0.00526 76363
[View Peptides]   TPA1 Poly(rA)-binding protein involved in translation termination efficiency, mRNA poly(A) tail length an... 2 2 6.8% 0.00564 74042
[View Peptides]   EAF1 Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 sub... 2 2 6.7% 0.00379 110041
[View Peptides]   EPS1 ER protein with chaperone and co-chaperone activity, involved in retention of resident ER proteins; ... 2 2 6.7% 0.00518 81219
[View Peptides]   SHM1 Mitochondrial serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahy... 2 6 6.7% 0.0222 53686
[View Peptides]   HRD1 Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfold... 2 2 6.4% 0.00659 63535
[View Peptides]   HAL5 Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disrupt... 2 2 6.2% 0.00425 95455
[View Peptides]   MSE1 Mitochondrial glutamyl-tRNA synthetase, predicted to be palmitoylated 2 2 6.2% 0.00677 61603
[View Peptides]   YPL150W Putative protein kinase of unknown cellular role 2 2 6.0% 0.00403 100646
[View Peptides]   HBT1 Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); m... 2 2 5.9% 0.00347 113616
[View Peptides]   LYS2 Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-... 3 3 5.7% 0.00391 155345
[View Peptides]   MIS1 Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation ... 2 2 5.3% 0.00372 106217
[View Peptides]   RET2 Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved... 2 2 5.1% 0.00665 60628
[View Peptides]   AFG3 Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation... 2 2 4.9% 0.00477 84544
[View Peptides]   YOL075C Putative ABC transporter 2 2 4.9% 0.00281 145157
[View Peptides]   NUP116 Subunit of the Nup82 subcomplex of the nuclear pore complex; localized to both sides of the pore; co... 2 2 4.2% 0.00326 116234
[View Peptides]   URN1 Putative protein of unknown function containing WW and FF domains; overexpression causes accumulatio... 2 2 4.1% 0.00781 54139
[View Peptides]   JEN1 Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is dere... 2 2 3.9% 0.00589 69376
[View Peptides]   GEM1 Evolutionarily-conserved tail-anchored outer mitochondrial membrane GTPase which regulates mitochond... 2 2 3.8% 0.00548 75150
[View Peptides]   CAB2 Probable phosphopantothenoylcysteine synthetase (PPCS), which catalyzes the second step of coenzyme ... 2 2 3.8% 0.00995 41893
[View Peptides]   VAS1 Mitochondrial and cytoplasmic valyl-tRNA synthetase 2 2 3.7% 0.00329 125770
[View Peptides]   AGX1 Alanine:glyoxylate aminotransferase (AGT), catalyzes the synthesis of glycine from glyoxylate, which... 2 2 3.6% 0.00943 41907
[View Peptides]   YMR196W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... 2 2 3.5% 0.00334 126624
[View Peptides]   YHR182W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... 2 2 3.4% 0.00463 90109
[View Peptides]   SAC3 Nuclear pore-associated protein, required for biogenesis of the small ribosomal subunit; forms a com... 2 2 3.4% 0.00279 149568
[View Peptides]   RIM15 Glucose-repressible protein kinase involved in signal transduction during cell proliferation in resp... 2 2 3.3% 0.00205 196530
[View Peptides]   YLR149C Putative protein of unknown function; overexpression causes a cell cycle delay or arrest; null mutat... 2 2 3.3% 0.00497 82799
[View Peptides]   UBX3 UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, green fluorescent... 2 2 3.1% 0.00798 52943
[View Peptides]   LYP1 Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of c... 2 2 2.9% 0.00594 68090
[View Peptides]   MDS3 Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expr... 2 2 2.8% 0.00244 167074
[View Peptides]   SIR4 Silent information regulator that, together with SIR2 and SIR3, is involved in assembly of silent ch... 2 2 2.8% 0.00267 152061
[View Peptides]   SHS1 One of five related septins (Cdc3p, Cdc10p, Cdc11p, Cdc12p, Shs1p) that form a cortical filamentous ... 2 2 2.7% 0.00659 62630
[View Peptides]   PDR12 Plasma membrane ATP-binding cassette (ABC) transporter, weak-acid-inducible multidrug transporter re... 2 2 2.5% 0.0024 171064
[View Peptides]   YJL113W Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 2 2 2.4% 0.00201 207708
[View Peptides]   SAK1 Upstream serine/threonine kinase for the SNF1 complex; partially redundant with Elm1p and Tos3p; mem... 2 2 2.4% 0.00318 126872
[View Peptides]   CIR2 Mitochondrial protein with similarity to flavoprotein-type oxidoreductases; found in a large supramo... 2 2 2.4% 0.00575 69634
[View Peptides]   APC1 Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein li... 2 2 2.3% 0.00208 196143
[View Peptides]   BPT1 ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the t... 2 2 2.1% 0.00233 176873
[View Peptides]   ALR1 Plasma membrane Mg(2+) transporter, expression and turnover are regulated by Mg(2+) concentration; o... 2 2 1.9% 0.00423 95869
[View Peptides]   FKS1 Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic sub... 2 2 1.7% 0.00194 214849
[View Peptides]   MLP1 Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the... 2 2 1.6% 0.00194 218454
[View Peptides]   GCN1 Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate ... 2 2 1.5% 0.00136 296697
[View Peptides]   NUP145 Essential nucleoporin, catalyzes its own cleavage in vivo to generate a C-terminal fragment that ass... 2 2 1.4% 0.00276 145661
[View Peptides]   TOM1 E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may reg... 2 2 1.3% 0.00111 374186
[View Peptides]   GID7 Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,... 2 2 1.3% 0.00487 84517
[View Peptides]   MET5 Sulfite reductase beta subunit, involved in amino acid biosynthesis, transcription repressed by meth... 2 2 1.2% 0.00252 161218
[View Peptides]   RAD5 DNA helicase proposed to promote replication fork regression during postreplication repair by templa... 2 2 1.2% 0.00311 134002
[View Peptides]   YLR278C Zinc-cluster protein; GFP-fusion protein localizes to the nucleus; mutant shows moderate growth defe... 2 2 1.1% 0.00271 151278
[View Peptides]   SNT2 DNA binding protein with similarity to the S. pombe Snt2 protein; computational analysis suggests a ... 2 2 1.0% 0.00259 163203

YRC Informatics Platform - Version 3.0
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