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Protein Overview: YLR149C

General Information:
Name(s) found: YLR149C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Putative protein of unknown function; overexpression causes a cell cycle delay or arrest; null mutation results in a decrease in plasma membrane electron transport; YLR149C is not an essential gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 730 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIDGTGQSK EALQDERLNT GSDKVYQNYM MPALELYDAK VSINHWQLRD CIKPGSMNQS  60
   61 KLYYIYDHSI RVLDTDSSVL RSPVRRHNSI QPSNSGKNST EKTSTKGSRT TGSYISKNLH 120
  121 VPSEKLVEFN FKPRCFTELN GLTVCGGLIG SDDKGFPSNW NRLAQDANIS LPPPSQPINI 180
  181 SKNISFPINS HYSNPNIWKG IVEFYNQETD TMMTFTLGQF INNCVTLYDR ASMQFDLFAC 240
  241 NNDGHLYQCD VSNRDVTLVK RYADLKFPLN NASLSHDGQT MVVSGDSNKF AVYNQNELTN 300
  301 QFSLHYDNHP SWGSSVNRVR RIPRFALPDE SEYIENIYEA PNSDHGFYNS FSENDLQFAT 360
  361 VFQNGTCAIY DIRNMATPMA EISSTRPHSH NGAFRVCRFS YGLDDLLFIS EHQGRVHVVD 420
  421 TRNYVNHQVI VIPDKVNMEY INERKHNTNH NFTTNNNNEN ESNDSKNELQ GADYRSLSRR 480
  481 RFSLPSMPNV TTEPWITMAQ RIPKKYLEPQ ILPFPKVMDK ISNESVLFST KGSSSSDVAH 540
  541 PYKRRCSFRV RRVSTSAPTA DYSNNNVNAS LGTPAADSIA TSSSNSAPQN LIDPLILSHQ 600
  601 QASNDVFEDD EYYEAYNDVH STYRVSSDYH GVSARAFESF LRPPSTPDLP SDDDNFAANS 660
  661 RNNRGTSNFL RRPVITTQES NEFSEENNIS GIDWVEDRNG SSLIIGTDYG IMRWNINSWA 720
  721 RRSFSSYDLC

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) VPS74 YLR149C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ASF1 3829 - low filter Green EM, et al (2005)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PCF11 YLR149C 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YLR149C Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..374] PSI-BLAST 59.0 Tup1, C-terminal domain
    2 View Details [375..533] PSI-BLAST 67.69897 beta1-subunit of the signal-transducing G protein heterotrimer
    3 View Details [534..730] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.145838346152539 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  0.145838346152539 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle