YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Sui1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 23 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AAT2
  • peroxisome
  • cytoplasm
  • glutamate metabolic process
  • nitrogen compound metabolic process
  • asparagine biosynthetic process from oxaloacetate
  • aspartate biosynthetic process
  • aspartate catabolic process
  • L-aspartate:2-oxoglutarate aminotransferase activity
  • ACS2
  • nucleus
  • cytosol
  • acetyl-CoA biosynthetic process
  • histone acetylation
  • acetate-CoA ligase activity
  • ADH4
  • mitochondrion
  • fermentation
  • NADH oxidation
  • alcohol dehydrogenase activity, zinc-dependent
  • ALA1
  • cytoplasm
  • mitochondrion
  • alanyl-tRNA aminoacylation
  • alanine-tRNA ligase activity
  • ARG4
  • cytosol
  • arginine biosynthetic process
  • argininosuccinate lyase activity
  • CAR2
  • nucleus
  • cytoplasm
  • arginine catabolic process
  • ornithine-oxo-acid transaminase activity
  • CDC60
  • cytoplasm
  • leucyl-tRNA aminoacylation
  • leucine-tRNA ligase activity
  • CPR1
  • nucleus
  • mitochondrion
  • histone deacetylase complex
  • ascospore formation
  • protein metabolic process
  • peptidyl-prolyl cis-trans isomerase activity
  • DED81
  • cytoplasm
  • asparaginyl-tRNA aminoacylation
  • ATP binding
  • asparagine-tRNA ligase activity
  • ENP1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • preribosome, small subunit precursor
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • ERG10
  • cytosol
  • ergosterol biosynthetic process
  • acetyl-CoA C-acetyltransferase activity
  • ERG20
  • cytosol
  • ergosterol biosynthetic process
  • isoprenoid biosynthetic process
  • farnesyl diphosphate biosynthetic process
  • geranyltranstransferase activity
  • dimethylallyltranstransferase activity
  • GRS1
  • cytoplasm
  • mitochondrion
  • glycyl-tRNA aminoacylation
  • transcription termination
  • glycine-tRNA ligase activity
  • ILS1
  • cytosol
  • translation
  • isoleucine-tRNA ligase activity
  • MPC54
  • spindle pole body
  • ascospore wall assembly
  • structural molecule activity
  • NAS6
  • proteasome regulatory particle
  • proteolysis
  • molecular_function
  • PDC5
  • nucleus
  • cytoplasm
  • cytosol
  • pyruvate metabolic process
  • glucose catabolic process to ethanol
  • pyruvate decarboxylase activity
  • SSZ1
  • cytoplasm
  • regulation of translational fidelity
  • translation
  • unfolded protein binding
  • SUI1
  • multi-eIF complex
  • translational initiation
  • translation initiation factor activity
  • THR4
  • nucleus
  • cytoplasm
  • endocytosis
  • threonine metabolic process
  • threonine synthase activity
  • TPS1
  • cytoplasm
  • alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)
  • carbohydrate metabolic process
  • response to drug
  • trehalose biosynthetic process
  • response to stress
  • alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
  • TRR1
  • cytoplasm
  • response to oxidative stress
  • thioredoxin-disulfide reductase activity
  • YDL124W
  • nucleus
  • cytoplasm
  • metabolic process
  • alpha-keto amide reductase activity
  • alpha-keto ester reductase activity
  • aldo-keto reductase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytoplasm 3.2262E-4 23 3552 21 6292
    cytosol 4.2225E-4 23 284 6 6292
    intracellular part 3.7561E-3 23 4938 23 6292
    intracellular 4.4613E-3 23 4975 23 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cellular amino acid metabolic process 2.8371E-7 23 199 8 6292
    cellular amine metabolic process 6.5711E-7 23 222 8 6292
    organic acid metabolic process 1.2363E-6 23 333 9 6292
    oxoacid metabolic process 1.2363E-6 23 333 9 6292
    carboxylic acid metabolic process 1.2363E-6 23 333 9 6292
    amine metabolic process 1.308E-6 23 243 8 6292
    cellular amino acid and derivative metabolic process 1.308E-6 23 243 8 6292
    cellular ketone metabolic process 1.7052E-6 23 346 9 6292
    small molecule metabolic process 3.368E-6 23 760 12 6292
    tRNA aminoacylation for protein translation 5.1773E-6 23 33 4 6292
    tRNA aminoacylation 5.1773E-6 23 33 4 6292
    amino acid activation 5.1773E-6 23 33 4 6292
    metabolic process 3.4356E-5 23 3157 21 6292
    primary metabolic process 5.5828E-5 23 2896 20 6292
    translation 2.7351E-4 23 376 7 6292
    glutamine family amino acid metabolic process 4.7875E-4 23 43 3 6292
    tRNA metabolic process 8.4163E-4 23 120 4 6292
    biosynthetic process 1.4629E-3 23 1602 13 6292
    arginine metabolic process 1.4869E-3 23 16 2 6292
    ncRNA metabolic process 2.0084E-3 23 257 5 6292
    fermentation 2.3335E-3 23 20 2 6292
    asparaginyl-tRNA aminoacylation 3.6554E-3 23 1 1 6292
    alanyl-tRNA aminoacylation 3.6554E-3 23 1 1 6292
    ergosterol metabolic process 3.9386E-3 23 26 2 6292
    phytosteroid metabolic process 3.9386E-3 23 26 2 6292
    phytosteroid biosynthetic process 3.9386E-3 23 26 2 6292
    ergosterol biosynthetic process 3.9386E-3 23 26 2 6292
    protein metabolic process 4.1389E-3 23 1136 10 6292
    cellular biosynthetic process 4.4238E-3 23 1567 12 6292
    cellular amino acid catabolic process 5.2251E-3 23 30 2 6292
    steroid biosynthetic process 5.9314E-3 23 32 2 6292
    sterol biosynthetic process 5.9314E-3 23 32 2 6292
    amine catabolic process 6.3001E-3 23 33 2 6292
    arginine catabolic process 7.2981E-3 23 2 1 6292
    leucyl-tRNA aminoacylation 7.2981E-3 23 2 1 6292
    glycyl-tRNA aminoacylation 7.2981E-3 23 2 1 6292
    farnesyl diphosphate biosynthetic process 7.2981E-3 23 2 1 6292
    farnesyl diphosphate metabolic process 7.2981E-3 23 2 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    aminoacyl-tRNA ligase activity 1.9023E-7 23 38 5 6292
    ligase activity, forming aminoacyl-tRNA and related compounds 1.9023E-7 23 38 5 6292
    ligase activity, forming carbon-oxygen bonds 1.9023E-7 23 38 5 6292
    ligase activity 1.1992E-5 23 150 6 6292
    catalytic activity 1.867E-5 23 2150 18 6292
    transferase activity, transferring nitrogenous groups 1.8874E-3 23 18 2 6292
    transaminase activity 1.8874E-3 23 18 2 6292
    ornithine-oxo-acid transaminase activity 3.6554E-3 23 1 1 6292
    geranyltranstransferase activity 3.6554E-3 23 1 1 6292
    alanine-tRNA ligase activity 3.6554E-3 23 1 1 6292
    C-acetyltransferase activity 3.6554E-3 23 1 1 6292
    threonine synthase activity 3.6554E-3 23 1 1 6292
    dimethylallyltranstransferase activity 3.6554E-3 23 1 1 6292
    alpha-keto amide reductase activity 3.6554E-3 23 1 1 6292
    acetyl-CoA C-acetyltransferase activity 3.6554E-3 23 1 1 6292
    alpha-keto ester reductase activity 3.6554E-3 23 1 1 6292
    argininosuccinate lyase activity 3.6554E-3 23 1 1 6292
    lyase activity 3.8242E-3 23 88 3 6292
    alcohol dehydrogenase activity, zinc-dependent 7.2981E-3 23 2 1 6292
    asparagine-tRNA ligase activity 7.2981E-3 23 2 1 6292
    thioredoxin-disulfide reductase activity 7.2981E-3 23 2 1 6292
    glycine-tRNA ligase activity 7.2981E-3 23 2 1 6292
    leucine-tRNA ligase activity 7.2981E-3 23 2 1 6292
    isoleucine-tRNA ligase activity 7.2981E-3 23 2 1 6292
    amidine-lyase activity 7.2981E-3 23 2 1 6292
    acetate-CoA ligase activity 7.2981E-3 23 2 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle