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The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Process by which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA. The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs). The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tRNA metabolic process
Acc: GO:0006399
Aspect: Biological Process
Desc: The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established.
Synonyms:
  • tRNA metabolism
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 1530 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006399 - tRNA metabolic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle