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Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of pyrophosphate and AMP. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate, to form aminoacyl-tRNA or a related compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: alanine-tRNA ligase activity
Acc: GO:0004813
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
Synonyms:
  • alanine-transfer RNA ligase activity
  • AlaRS
  • alanine translase activity
  • alanine tRNA synthetase activity
  • alanyl-tRNA synthetase activity
  • Ala-tRNA synthetase activity
  • alanyl-transfer RNA synthetase activity
  • L-alanine:tRNAAla ligase (AMP-forming)
  • alanyl-transfer ribonucleate synthetase activity
  • alanyl-transfer ribonucleic acid synthetase activity
  • alanine transfer RNA synthetase activity
  • alanyl-transfer ribonucleate synthase activity
Proteins in PDR annotated with:
   This term: 38 [Search]
   Term or descendants: 38 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004813 - alanine-tRNA ligase activity (interactive image map)
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