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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Sds22. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 15 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
GLC7
  • protein phosphatase type 1 complex
  • mRNA cleavage and polyadenylation specificity factor complex
  • cellular bud neck
  • spindle pole body
  • nuclear outer membrane
  • nucleolus
  • mating projection base
  • mitotic cell cycle spindle assembly checkpoint
  • cell morphogenesis during vegetative growth
  • protein amino acid dephosphorylation
  • chromosome segregation
  • cell budding
  • cellular ion homeostasis
  • meiosis
  • regulation of carbohydrate metabolic process
  • ascospore formation
  • response to heat
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • glycogen metabolic process
  • termination of RNA polymerase II transcription, poly(A)-independent
  • histone dephosphorylation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • RNA binding
  • metal ion binding
  • hydrolase activity
  • HXT6
  • mitochondrion
  • plasma membrane
  • hexose transport
  • fructose transmembrane transporter activity
  • glucose transmembrane transporter activity
  • mannose transmembrane transporter activity
  • KOG1
  • fungal-type vacuole membrane
  • mitochondrion
  • TORC1 complex
  • plasma membrane
  • regulation of cell growth
  • cellular response to starvation
  • molecular_function
  • NET1
  • RENT complex
  • nucleolus
  • chromatin silencing at rDNA
  • nucleolus organization
  • regulation of exit from mitosis
  • rDNA binding
  • NOP6
  • nucleolus
  • rRNA processing
  • molecular_function
  • NSR1
  • nucleus
  • mitochondrion
  • nucleolus
  • telomere maintenance
  • ribosomal small subunit assembly
  • rRNA processing
  • RNA binding
  • single-stranded DNA binding
  • PMA1
  • mitochondrion
  • membrane raft
  • plasma membrane
  • proton transport
  • regulation of pH
  • hydrogen-exporting ATPase activity, phosphorylative mechanism
  • PMA2
  • mitochondrion
  • plasma membrane
  • proton transport
  • regulation of pH
  • hydrogen-exporting ATPase activity, phosphorylative mechanism
  • PPZ2
  • cellular_component
  • cellular sodium ion homeostasis
  • protein serine/threonine phosphatase activity
  • REG1
  • protein phosphatase type 1 complex
  • cytoplasm
  • negative regulation of transcription from RNA polymerase II promoter
  • regulation of carbohydrate metabolic process
  • glycogen metabolic process
  • vacuolar protein catabolic process
  • protein phosphatase type 1 regulator activity
  • RSE1
  • U2 snRNP
  • spliceosome assembly
  • nuclear mRNA splicing, via spliceosome
  • U2 snRNA binding
  • RVB1
  • nucleus
  • Swr1 complex
  • Ino80 complex
  • chromatin remodeling complex
  • chromatin remodeling
  • regulation of transcription from RNA polymerase II promoter
  • ATPase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • SDS22
  • nucleus
  • cytoplasm
  • protein targeting
  • chromosome segregation
  • protein phosphatase type 1 regulator activity
  • enzyme regulator activity
  • SNF4
  • nucleus
  • cytoplasm
  • nuclear envelope lumen
  • plasma membrane
  • AMP-activated protein kinase complex
  • peroxisome organization
  • protein amino acid phosphorylation
  • replicative cell aging
  • positive regulation of gluconeogenesis
  • regulation of transcription from RNA polymerase II promoter
  • AMP-activated protein kinase activity
  • protein serine/threonine kinase activator activity
  • YGR130C
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein phosphatase type 1 complex 1.1065E-4 15 7 2 6292
    plasma membrane 2.8525E-4 15 268 5 6292
    protein serine/threonine phosphatase complex 7.0676E-4 15 17 2 6292
    nucleolus 1.2539E-3 15 211 4 6292
    nuclear part 8.6963E-3 15 1103 7 6292
    RENT complex 9.5041E-3 15 4 1 6292
    nuclear envelope lumen 9.5041E-3 15 4 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    regulation of carbohydrate metabolic process 7.4674E-5 15 36 3 6292
    biological regulation 7.9692E-5 15 1213 10 6292
    monovalent inorganic cation homeostasis 8.7975E-5 15 38 3 6292
    chemical homeostasis 1.6067E-4 15 123 4 6292
    ion homeostasis 1.6067E-4 15 123 4 6292
    RNA metabolic process 6.452E-4 15 954 8 6292
    regulation of biological quality 1.1039E-3 15 551 6 6292
    hydrogen transport 1.4205E-3 15 24 2 6292
    proton transport 1.4205E-3 15 24 2 6292
    homeostatic process 1.9507E-3 15 408 5 6292
    cation homeostasis 1.9772E-3 15 109 3 6292
    glucose metabolic process 1.9772E-3 15 109 3 6292
    regulation of pH 2.0753E-3 15 29 2 6292
    monovalent inorganic cation transport 2.3703E-3 15 31 2 6292
    glycogen metabolic process 2.5249E-3 15 32 2 6292
    energy reserve metabolic process 2.5249E-3 15 32 2 6292
    hexose metabolic process 2.8586E-3 15 124 3 6292
    monosaccharide metabolic process 3.6382E-3 15 135 3 6292
    cellular glucan metabolic process 4.5277E-3 15 43 2 6292
    glucan metabolic process 4.5277E-3 15 43 2 6292
    gene expression 4.7582E-3 15 1283 8 6292
    nucleolus organization 4.7627E-3 15 2 1 6292
    histone dephosphorylation 4.7627E-3 15 2 1 6292
    transcription, DNA-dependent 4.8935E-3 15 503 5 6292
    RNA biosynthetic process 5.107E-3 15 508 5 6292
    regulation of primary metabolic process 5.372E-3 15 514 5 6292
    transcription from RNA polymerase II promoter 6.7464E-3 15 335 4 6292
    regulation of metabolic process 7.0111E-3 15 547 5 6292
    cellular sodium ion homeostasis 7.136E-3 15 3 1 6292
    sodium ion homeostasis 7.136E-3 15 3 1 6292
    transcription 7.2876E-3 15 552 5 6292
    regulation of cellular process 7.3152E-3 15 796 6 6292
    cellular polysaccharide metabolic process 7.324E-3 15 55 2 6292
    regulation of transcription, DNA-dependent 8.5232E-3 15 358 4 6292
    polysaccharide metabolic process 8.6698E-3 15 60 2 6292
    regulation of biological process 8.6743E-3 15 824 6 6292
    nucleic acid metabolic process 8.9153E-3 15 1415 8 6292
    regulation of RNA metabolic process 8.9471E-3 15 363 4 6292
    positive regulation of gluconeogenesis 9.5041E-3 15 4 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    hydrogen-exporting ATPase activity, phosphorylative mechanism 5.3053E-6 15 2 2 6292
    protein phosphatase type 1 regulator activity 3.4536E-4 15 12 2 6292
    ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 4.7486E-4 15 14 2 6292
    protein phosphatase regulator activity 1.304E-3 15 23 2 6292
    phosphatase regulator activity 1.304E-3 15 23 2 6292
    protein serine/threonine phosphatase activity 1.6681E-3 15 26 2 6292
    ATPase activity, coupled to transmembrane movement of ions 2.0753E-3 15 29 2 6292
    U2 snRNA binding 2.384E-3 15 1 1 6292
    phosphoprotein phosphatase activity 4.5277E-3 15 43 2 6292
    protein serine/threonine kinase activator activity 4.7627E-3 15 2 1 6292
    ATPase activity, coupled 4.8042E-3 15 149 3 6292
    hydrogen ion transmembrane transporter activity 7.0673E-3 15 54 2 6292
    primary active transmembrane transporter activity 7.324E-3 15 55 2 6292
    ATPase activity, coupled to transmembrane movement of substances 7.324E-3 15 55 2 6292
    P-P-bond-hydrolysis-driven transmembrane transporter activity 7.324E-3 15 55 2 6292
    hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 7.324E-3 15 55 2 6292
    monovalent inorganic cation transmembrane transporter activity 8.3923E-3 15 59 2 6292
    ATPase activity, coupled to movement of substances 8.3923E-3 15 59 2 6292

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