YRC Public Data Repository - Protein Complex GO Analysis

Complex Overview

From Publication:	Gavin A.C. et al. (2002) Abstract Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature. 2002 Jan 10;415(6868):141-7.
Notes:	From the published set of protein complexes.
Complex Size:	29 proteins

Complex Member Proteins

Protein	GO Cellular Component	GO Biological Process	GO Molecular Function
AMS1	vacuolar membrane	carbohydrate metabolic process oligosaccharide catabolic process	alpha-mannosidase activity
ASC1	cytoplasm	telomere maintenance negative regulation of translation	molecular_function
CDC14	nucleus RENT complex spindle pole body nucleolus	regulation of exit from mitosis protein amino acid dephosphorylation	phosphoprotein phosphatase activity
DHH1	cytoplasm cytoplasmic mRNA processing body	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay deadenylation-dependent decapping of nuclear-transcribed mRNA	protein binding RNA helicase activity
FBA1	cytoplasm mitochondrion cytosol	gluconeogenesis glycolysis	fructose-bisphosphate aldolase activity
MAF1	nucleus	negative regulation of transcription from RNA polymerase III promoter	transcription regulator activity
RET1	DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter	DNA-directed RNA polymerase activity
RPA12	DNA-directed RNA polymerase I complex	transcription from RNA polymerase I promoter ribosome biogenesis	DNA-directed RNA polymerase activity
RPA135	DNA-directed RNA polymerase I complex	transcription from RNA polymerase I promoter ribosome biogenesis	DNA-directed RNA polymerase activity
RPA190	DNA-directed RNA polymerase I complex	transcription from RNA polymerase I promoter	DNA-directed RNA polymerase activity
RPA43	DNA-directed RNA polymerase I complex	transcription from RNA polymerase I promoter ribosome biogenesis	DNA-directed RNA polymerase activity
RPA49	DNA-directed RNA polymerase I complex	transcription from RNA polymerase I promoter regulation of cell size ribosome biogenesis	DNA-directed RNA polymerase activity
RPB10	DNA-directed RNA polymerase I complex DNA-directed RNA polymerase III complex DNA-directed RNA polymerase II, core complex	transcription from RNA polymerase III promoter transcription from RNA polymerase I promoter transcription from RNA polymerase II promoter	DNA-directed RNA polymerase activity
RPB5	DNA-directed RNA polymerase I complex DNA-directed RNA polymerase III complex DNA-directed RNA polymerase II, core complex	transcription from RNA polymerase III promoter transcription from RNA polymerase I promoter transcription from RNA polymerase II promoter	DNA-directed RNA polymerase activity
RPB8	DNA-directed RNA polymerase I complex DNA-directed RNA polymerase III complex DNA-directed RNA polymerase II, core complex	transcription from RNA polymerase III promoter transcription from RNA polymerase I promoter transcription from RNA polymerase II promoter	DNA-directed RNA polymerase activity
RPC11	DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter	DNA-directed RNA polymerase activity
RPC17	DNA-directed RNA polymerase III complex	transcription initiation from RNA polymerase III promoter	DNA-directed RNA polymerase activity
RPC19	DNA-directed RNA polymerase I complex DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter transcription from RNA polymerase I promoter ribosome biogenesis	DNA-directed RNA polymerase activity
RPC25	DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter	DNA-directed RNA polymerase activity
RPC31	DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter	DNA-directed RNA polymerase activity
RPC34	nucleus cytoplasm mitochondrion DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter ribosome biogenesis	DNA-directed RNA polymerase activity
RPC37	DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter	DNA-directed RNA polymerase activity
RPC40	DNA-directed RNA polymerase I complex DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter transcription from RNA polymerase I promoter ribosome biogenesis	DNA-directed RNA polymerase activity
RPC53	DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter	DNA-directed RNA polymerase activity
RPC82	DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter ribosome biogenesis	DNA-directed RNA polymerase activity
RPO26	DNA-directed RNA polymerase I complex DNA-directed RNA polymerase III complex DNA-directed RNA polymerase II, core complex	transcription from RNA polymerase III promoter transcription from RNA polymerase I promoter transcription from RNA polymerase II promoter	DNA-directed RNA polymerase activity
RPO31	DNA-directed RNA polymerase III complex	transcription from RNA polymerase III promoter	DNA-directed RNA polymerase activity
RSC8	nucleus RSC complex	ATP-dependent chromatin remodeling double-strand break repair via nonhomologous end joining	DNA-dependent ATPase activity
SRO7	cytosol plasma membrane	small GTPase mediated signal transduction Golgi to plasma membrane transport exocytosis	SNARE binding Rab GTPase binding

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
DNA-directed RNA polymerase complex	1.6695E-46	29	31	21	6292
RNA polymerase complex	1.6695E-46	29	31	21	6292
nuclear DNA-directed RNA polymerase complex	1.6695E-46	29	31	21	6292
DNA-directed RNA polymerase III complex	4.0694E-39	29	17	16	6292
DNA-directed RNA polymerase I complex	8.2223E-25	29	14	11	6292
nuclear lumen	4.348E-20	29	453	22	6292
nucleolar part	1.7275E-19	29	45	12	6292
organelle lumen	1.5885E-16	29	660	22	6292
intracellular organelle lumen	1.5885E-16	29	660	22	6292
membrane-enclosed lumen	5.6423E-16	29	700	22	6292
nucleoplasm part	7.4352E-16	29	245	16	6292
nucleoplasm	2.4524E-15	29	264	16	6292
nuclear part	5.3835E-13	29	1103	23	6292
protein complex	1.0498E-12	29	1137	23	6292
nucleolus	4.6571E-11	29	211	12	6292
macromolecular complex	2.2847E-10	29	1635	24	6292
nucleus	3.1539E-8	29	2041	24	6292
DNA-directed RNA polymerase II, core complex	1.7567E-7	29	12	4	6292
intracellular organelle part	3.5464E-7	29	2282	24	6292
organelle part	3.5464E-7	29	2282	24	6292
DNA-directed RNA polymerase II, holoenzyme	1.133E-4	29	56	4	6292
membrane-bounded organelle	4.5054E-4	29	3771	26	6292
intracellular membrane-bounded organelle	4.5054E-4	29	3771	26	6292
non-membrane-bounded organelle	6.1407E-4	29	959	12	6292
intracellular non-membrane-bounded organelle	6.1407E-4	29	959	12	6292
intracellular part	8.7176E-4	29	4938	29	6292
intracellular	1.0831E-3	29	4975	29	6292
intracellular organelle	2.3461E-3	29	4070	26	6292
organelle	2.3583E-3	29	4071	26	6292

Biological Process Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
transcription from RNA polymerase III promoter	1.3765E-32	29	38	17	6292
transcription from RNA polymerase I promoter	1.183E-19	29	30	11	6292
transcription, DNA-dependent	4.3292E-19	29	503	22	6292
RNA biosynthetic process	5.3757E-19	29	508	22	6292
transcription	3.2974E-18	29	552	22	6292
RNA metabolic process	2.1661E-14	29	954	23	6292
nucleic acid metabolic process	4.8583E-13	29	1415	25	6292
cellular macromolecule biosynthetic process	2.6978E-12	29	1187	23	6292
macromolecule biosynthetic process	2.7991E-12	29	1189	23	6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	5.5526E-12	29	1566	25	6292
gene expression	1.4724E-11	29	1283	23	6292
cellular biosynthetic process	8.7619E-11	29	1567	24	6292
cellular nitrogen compound metabolic process	1.026E-10	29	1770	25	6292
nitrogen compound metabolic process	1.3565E-10	29	1791	25	6292
biosynthetic process	1.443E-10	29	1602	24	6292
cellular macromolecule metabolic process	3.393E-9	29	2285	26	6292
primary metabolic process	5.5274E-9	29	2896	28	6292
macromolecule metabolic process	6.6751E-9	29	2349	26	6292
metabolic process	5.8085E-8	29	3157	28	6292
cellular metabolic process	3.0653E-7	29	3033	27	6292
ribosome biogenesis	1.1942E-4	29	346	8	6292
ribonucleoprotein complex biogenesis	2.054E-4	29	374	8	6292
cellular process	4.8039E-4	29	4426	28	6292
cellular component biogenesis	2.994E-3	29	694	9	6292
negative regulation of transcription from RNA polymerase III promoter	4.609E-3	29	1	1	6292

Molecular Function Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
RNA polymerase activity	3.4803E-45	29	34	21	6292
DNA-directed RNA polymerase activity	3.4803E-45	29	34	21	6292
nucleotidyltransferase activity	9.1004E-28	29	168	21	6292
transferase activity, transferring phosphorus-containing groups	3.3295E-19	29	420	21	6292
transferase activity	1.7837E-13	29	797	21	6292
catalytic activity	7.5808E-10	29	2150	26	6292
alpha-mannosidase activity	4.609E-3	29	1	1	6292
fructose-bisphosphate aldolase activity	4.609E-3	29	1	1	6292

View Protein Complex Details

Complex Overview

Complex Member Proteins

Cellular Component Analysis

Biological Process Analysis

Molecular Function Analysis