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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

epsilon DNA polymerase complex 2.4099E-10 3 5 3 6292
DNA polymerase complex 2.8918E-9 3 10 3 6292
nuclear replisome 1.9664E-8 3 18 3 6292
replisome 1.9664E-8 3 18 3 6292
nuclear replication fork 2.7472E-8 3 20 3 6292
nucleotide-excision repair complex 3.2051E-8 3 21 3 6292
replication fork 2.7665E-7 3 42 3 6292
protein-DNA complex 7.0513E-7 3 57 3 6292
nuclear chromosome part 2.7115E-5 3 190 3 6292
nuclear chromosome 4.698E-5 3 228 3 6292
chromosomal part 5.2792E-5 3 237 3 6292
chromosome 8.1719E-5 3 274 3 6292
chromatin accessibility complex 1.9063E-3 3 4 1 6292
non-membrane-bounded organelle 3.5313E-3 3 959 3 6292
intracellular non-membrane-bounded organelle 3.5313E-3 3 959 3 6292
nuclear part 5.3751E-3 3 1103 3 6292
protein complex 5.8881E-3 3 1137 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 1.0965E-8 3 15 3 6292
lagging strand elongation 1.9664E-8 3 18 3 6292
DNA strand elongation 1.0832E-7 3 31 3 6292
DNA strand elongation involved in DNA replication 1.0832E-7 3 31 3 6292
DNA-dependent DNA replication 2.1342E-6 3 82 3 6292
DNA replication 7.2927E-6 3 123 3 6292
mismatch repair 5.3064E-5 3 27 2 6292
nucleotide-excision repair 1.0615E-4 3 38 2 6292
chromatin silencing at telomere 2.2383E-4 3 55 2 6292
negative regulation of gene expression, epigenetic 7.4253E-4 3 100 2 6292
chromatin silencing 7.4253E-4 3 100 2 6292
gene silencing 7.4253E-4 3 100 2 6292
regulation of gene expression, epigenetic 7.4253E-4 3 100 2 6292
DNA metabolic process 7.9998E-4 3 585 3 6292
negative regulation of transcription, DNA-dependent 1.8258E-3 3 157 2 6292
negative regulation of RNA metabolic process 1.849E-3 3 158 2 6292
DNA synthesis involved in DNA repair 1.9063E-3 3 4 1 6292
negative regulation of gene expression 1.9912E-3 3 164 2 6292
negative regulation of transcription 1.9912E-3 3 164 2 6292
negative regulation of macromolecule biosynthetic process 2.2655E-3 3 175 2 6292
negative regulation of nitrogen compound metabolic process 2.3959E-3 3 180 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.3959E-3 3 180 2 6292
negative regulation of biosynthetic process 2.6396E-3 3 189 2 6292
negative regulation of cellular biosynthetic process 2.6396E-3 3 189 2 6292
DNA repair 2.7234E-3 3 192 2 6292
negative regulation of macromolecule metabolic process 2.7234E-3 3 192 2 6292
negative regulation of cellular metabolic process 3.2225E-3 3 209 2 6292
negative regulation of metabolic process 3.2531E-3 3 210 2 6292
response to DNA damage stimulus 4.0991E-3 3 236 2 6292
negative regulation of cellular process 4.5939E-3 3 250 2 6292
negative regulation of biological process 4.7035E-3 3 253 2 6292
cellular response to stress 6.1581E-3 3 290 2 6292
cellular macromolecule biosynthetic process 6.7003E-3 3 1187 3 6292
macromolecule biosynthetic process 6.7343E-3 3 1189 3 6292
regulation of transcription, DNA-dependent 9.321E-3 3 358 2 6292
regulation of RNA metabolic process 9.5782E-3 3 363 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

double-stranded DNA binding 4.2679E-8 3 23 3 6292
structure-specific DNA binding 3.1916E-7 3 44 3 6292
DNA-directed DNA polymerase activity 5.201E-6 3 110 3 6292
DNA polymerase activity 5.9501E-6 3 115 3 6292
nucleotidyltransferase activity 1.8706E-5 3 168 3 6292
DNA binding 6.6597E-5 3 256 3 6292
transferase activity, transferring phosphorus-containing groups 2.9545E-4 3 420 3 6292
nucleic acid binding 1.1811E-3 3 666 3 6292
transferase activity 2.0257E-3 3 797 3 6292
zinc ion binding 3.8101E-3 3 8 1 6292
binding 8.6823E-3 3 1294 3 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle