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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 14 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ENP1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • preribosome, small subunit precursor
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • NOP14
  • mitochondrion
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • snoRNA binding
  • RPS13
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP4
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 7.048E-20 14 72 11 6292
    ribonucleoprotein complex 8.1265E-14 14 514 13 6292
    nuclear outer membrane 2.4579E-12 14 86 8 6292
    nuclear membrane 6.6316E-12 14 97 8 6292
    nucleolus 7.8441E-11 14 211 9 6292
    outer membrane 9.1168E-10 14 178 8 6292
    organelle outer membrane 9.1168E-10 14 178 8 6292
    nuclear envelope 2.2222E-9 14 199 8 6292
    preribosome 6.5582E-9 14 34 5 6292
    nuclear membrane-endoplasmic reticulum network 7.5206E-9 14 232 8 6292
    nuclear lumen 6.9578E-8 14 453 9 6292
    macromolecular complex 2.5299E-7 14 1635 13 6292
    endomembrane system 5.1269E-7 14 398 8 6292
    organelle lumen 1.798E-6 14 660 9 6292
    intracellular organelle lumen 1.798E-6 14 660 9 6292
    membrane-enclosed lumen 2.9679E-6 14 700 9 6292
    envelope 3.1752E-6 14 505 8 6292
    organelle envelope 3.1752E-6 14 505 8 6292
    non-membrane-bounded organelle 3.608E-6 14 959 10 6292
    intracellular non-membrane-bounded organelle 3.608E-6 14 959 10 6292
    nuclear part 1.3343E-5 14 1103 10 6292
    membrane part 2.429E-5 14 662 8 6292
    organelle membrane 3.3735E-5 14 692 8 6292
    small-subunit processome 6.8619E-5 14 6 2 6292
    preribosome, small subunit precursor 6.8619E-5 14 6 2 6292
    90S preribosome 6.135E-4 14 17 2 6292
    intracellular organelle part 1.5376E-3 14 2282 11 6292
    organelle part 1.5376E-3 14 2282 11 6292
    membrane 1.6969E-3 14 1198 8 6292
    nucleus 3.1891E-3 14 2041 10 6292
    Noc4p-Nop14p complex 4.4455E-3 14 2 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    maturation of SSU-rRNA 2.2973E-18 14 59 10 6292
    rRNA processing 5.5355E-17 14 128 11 6292
    rRNA metabolic process 1.1995E-16 14 137 11 6292
    ribosome biogenesis 4.5104E-16 14 346 13 6292
    ribonucleoprotein complex biogenesis 1.2565E-15 14 374 13 6292
    ncRNA processing 1.9174E-14 14 215 11 6292
    ncRNA metabolic process 1.3984E-13 14 257 11 6292
    cellular component biogenesis 4.0713E-12 14 694 13 6292
    RNA processing 1.0478E-11 14 380 11 6292
    RNA metabolic process 2.1648E-7 14 954 11 6292
    gene expression 2.985E-7 14 1283 12 6292
    nucleic acid metabolic process 1.3226E-5 14 1415 11 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.7241E-5 14 1566 11 6292
    cellular nitrogen compound metabolic process 1.2791E-4 14 1770 11 6292
    nitrogen compound metabolic process 1.439E-4 14 1791 11 6292
    cellular macromolecule metabolic process 2.0876E-4 14 2285 12 6292
    macromolecule metabolic process 2.8291E-4 14 2349 12 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.5365E-4 14 13 2 6292
    rRNA modification 6.8931E-4 14 18 2 6292
    ribosomal small subunit biogenesis 1.4494E-3 14 26 2 6292
    primary metabolic process 2.7048E-3 14 2896 12 6292
    cellular metabolic process 4.3936E-3 14 3033 12 6292
    metabolic process 6.6576E-3 14 3157 12 6292
    ncRNA 5'-end processing 6.6614E-3 14 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.6614E-3 14 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.6614E-3 14 3 1 6292
    rRNA 5'-end processing 6.6614E-3 14 3 1 6292
    RNA 5'-end processing 6.6614E-3 14 3 1 6292
    cellular process 7.2188E-3 14 4426 14 6292
    maturation of 5.8S rRNA 8.8726E-3 14 4 1 6292
    cleavage involved in rRNA processing 8.8726E-3 14 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 3.8301E-16 14 31 8 6292
    RNA binding 2.7386E-7 14 367 8 6292
    nucleic acid binding 2.5401E-5 14 666 8 6292
    binding 2.858E-3 14 1294 8 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle