Protein Overview: PEX18

General Information:
Name(s) found:	PEX18 / YHR160C [SGD]
Description(s) found: Found 26 descriptions. SHOW ALL	Peroxin required for targeting of peroxisomal matrix proteins containing PTS2; interacts with Pex7p; partially redundant with Pex21p [SGD]
Organism:	Saccharomyces cerevisiae
Length:	283 amino acids
Gene Ontology:
Cellular Component:	peroxisome [IDA] cytosol [IDA]
Biological Process:	protein targeting to peroxisome [IMP][IPI]
Molecular Function:	protein binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSNRCQTNE VNKFISSTEK GPFTGRDNTL SFNKIGSRLN SPPILKDKIE LKFLQHSEDL  60
   61 NQSRSYVNIR PRTLEDQSYK FEAPNLNDNE TSWAKDFRYN FPKNVEPPIE NQIANLNINN 120
  121 GLRTSQTDFP LGFYSQKNFN IASFPVVDHQ IFKTTGLEHP INSHIDSLIN AEFSELEASS 180
  181 LEEDVHTEEE NSGTSLEDEE TAMKGLASDI IEFCDNNSAN KDVKERLNSS KFMGLMGSIS 240
  241 DGSIVLKKDN GTERNLQKHV GFCFQNSGNW AGLEFHDVED RIA

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		PEX18 PEX21 PEX5 PEX8

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PEX13	PEX18	2	Unpublished Fields Lab Data
View Screen	RPN11	PEX18	2	Unpublished Fields Lab Data
View Screen	TEM1	PEX18	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..283]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2