Protein Overview: TS101_RAT

General Information:
Name(s) found:	TS101_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|71153364\|sp\|Q6IRE4.1\|TS101_RAT RecName: Full=Tumor susceptibility gene 101 protein; AltName: Full=ESCRT-I complex subunit TSG101 [NCBI NR] gi\|48374087\|ref\|NP_853659.2\| tumor susceptibility gene 101 [Rattus norvegicus] [NCBI NR] gi\|47718036\|gb\|AAH70951.1\| Tumor susceptibility gene 101 [Rattus norvegicus] [NCBI NR] gi\|149055816\|gb\|EDM07247.1\| tumor susceptibility gene 101 [Rattus norvegicus] [NCBI NR] Tumor susceptibility gene 101 protein OS=Rattus norvegicus GN=Tsg101 PE=1 SV=1 [Swiss-Prot] tumor susceptibility gene 101; Tumor supressor gene [071204_hmrz_cont.fasta] tumor susceptibility gene 101 [Rattus norvegicus]gi\|47718036\|gb\|AAH70951.1\| Tumor susceptibility gene 101 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Tumor susceptibility gene 101 protein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Tumor susceptibility gene 101 [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Tumor susceptibility gene 101 protein [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] tumor susceptibility gene 101 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tumor susceptibility gene 101 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TUMOR SUSCEPTIBILITY GENE 101 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Tsg101 Tumor susceptibility gene 101 protein [rat-ipi-250309-contam.fasta] Tumor susceptibility gene 101 protein OS=Rattus norvegicus GN=Tsg101 [011711_HMR.fasta] Isoform of Q6IRE4, Tumor susceptibility gene 101 OS=Rattus norvegicus GN=Tsg101 PE=1 SV=3 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	391 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] late endosome membrane [IEA] endosome [IEA] cytoplasm [UNKNOWN][ISS] late endosome [UNKNOWN] nucleolus [UNKNOWN][IEA] plasma membrane [UNKNOWN][IEA]
Biological Process:	cell cycle arrest [UNKNOWN][IEA] negative regulation of cell proliferation [UNKNOWN][IEA] protein transport [IEA] non-lytic virus budding [UNKNOWN][ISS] protein monoubiquitination [IDA] post-translational protein modification [IEA] cell cycle [IEA] regulation of protein metabolic process [IEA] cell division [IEA] keratinocyte differentiation [UNKNOWN][IEA] negative regulation of transcription, DNA-dependent [UNKNOWN][IEA] regulation of cell growth [UNKNOWN][IEA] ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [UNKNOWN][IEA] cell differentiation [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN] transcription corepressor activity [UNKNOWN][IEA] ligand-dependent nuclear receptor transcription coactivator activity [IDA] calcium-dependent protein binding [UNKNOWN][IEA] small conjugating protein ligase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVSESQLKK MMSKYKYRDL TVRQTVNVIA MYKDLKPVLD SYVFNDGSSR ELVNLTGTIP  60
   61 VRYRGNIYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHDWKHP 120
  121 RSELLELIQI MIVIFGEEPP VFSRPTVSAS YPPYTAAGPP NTSYLPSMPS GISAYPSGYP 180
  181 PNPSGYPGCP YPPAGPYPAT TSSQYPSQPP VTTAGPSRDG TISEDTIRAS LISAVSDKLR 240
  241 WRMKEEMDGA QAELNALKRT EEDLKKGHQK LEEMVTRLDQ EVAEVDKNIE LLKKKDEELS 300
  301 SALEKMENQS ENNDIDEVII PTAPLYKQIL NLYAEENAIE DTIFYLGEAL RRGVIDLDVF 360
  361 LKHVRLLSRK QFQLRALMQK ARKTAGLSDL Y

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: TS101_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: