Protein Overview: gi|38454316, gi|...

General Information:
Name(s) found:	gi\|38454316 [NCBI NR] gi\|33438238 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|38454316\|ref\|NP_942086.1\| toll-like receptor 3 [Rattus norvegicus] [NCBI NR] gi\|33438238\|dbj\|BAC81504.1\| toll-like receptor 3 [Rattus norvegicus] [NCBI NR] toll-like receptor 3 [HMR_022704-rand.fasta] toll-like receptor 3 [Rattus norvegicus]gi\|33438238\|dbj\|BAC81504.1\| toll-like receptor 3 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Toll-like receptor 3 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] toll-like receptor 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TOLL-LIKE RECEPTOR 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Tlr3 Toll-like receptor 3 [rat-ipi-250309-contam.fasta] Toll-like receptor 3 OS=Rattus norvegicus GN=Tlr3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	905 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [UNKNOWN][IEA] membrane [IEA] integral to membrane [IEA] endosome membrane [UNKNOWN] [NOT]cell surface [UNKNOWN]
Biological Process:	I-kappaB phosphorylation [UNKNOWN][IEA] positive regulation of toll-like receptor signaling pathway [UNKNOWN][IEA] signal transduction [IEA] microglial cell activation during immune response [IDA] positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN][IEA] response to dsRNA [IDA] positive regulation of interferon-alpha biosynthetic process [UNKNOWN][ISS] defense response [UNKNOWN] response to virus [UNKNOWN][IEA] positive regulation of NF-kappaB import into nucleus [UNKNOWN][IEA] positive regulation of NF-kappaB transcription factor activity [UNKNOWN][IEA] positive regulation of interferon-beta biosynthetic process [UNKNOWN][ISS] toll-like receptor signaling pathway [IDA] positive regulation of interleukin-8 production [UNKNOWN][IEA] positive regulation of interferon-gamma biosynthetic process [UNKNOWN][ISS] response to exogenous dsRNA [UNKNOWN][IEA] innate immune response [IEA] positive regulation of JNK cascade [UNKNOWN][IEA] pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity [IDA] positive regulation of tumor necrosis factor production [UNKNOWN][IEA] positive regulation of chemokine production [UNKNOWN][IEA] positive regulation of interleukin-6 production [UNKNOWN][IEA] positive regulation of chemokine biosynthetic process [UNKNOWN][IEA]
Molecular Function:	transmembrane receptor activity [IEA] protein binding [IEA] double-stranded RNA binding [UNKNOWN][IDA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGRSSYLIY SFGGLLSLWI LVVSSTNQCT VRYNVADCSH LKLTHIPDDL PSNITVLNLT  60
   61 HNQLRGLPPA NFTRYSQLAL LDAGFNSISK LEPELCQILP LLKVLNLQHN ELSQISDQTF 120
  121 AFCTNLTELH LMSNSIRKIK SNPFKNQKSL IKLDLSHNGL SSTKLGTWVQ LENLQELLLA 180
  181 KNKIFALRNE ELDFLGNSSL QKLDLSSNPL KEFSPGCFHA IGKLFVLLLN NAQLNLDLTE 240
  241 KLCWELSNTS IQNLSLANNQ LLATSNSTFS GLKQTNLTSL DLSYNSLRDV GNDAFSWLPH 300
  301 LKYLSLEYNN IQRLTPHSFR GLSNLRYLSL KRAFTKQSVA LASHPNIDDF SFQWLKCLEH 360
  361 LNMDDNTIPG IKSNTFTGLV SLKYLSLSKT FTGLQTLTNE TFVSLTHSPL LTLNLTKNHI 420
  421 SKIASGTFSW LGQLRILDLG LNEIEQELTG QEWRGLGNIF EIYLSYNKYL QLTSKSFTLV 480
  481 PSLQRLMLRR VALKSVDISP SPFRPLYNLT ILDLSNNNIA NLNEDLLEGL ENLEILDFQH 540
  541 NNLARLWKHA NPGGPVNFLK GLSHLHILNL ESNGLDEIPV KVFKNLFELK SINLGLNNLN 600
  601 TLLPSIFDDQ TSLRSLNLQK NLITSVEKSV FGPAFHNLNS LDMSFNPFDC TCESIAWFVT 660
  661 WLNQTHTNIP ELSTHYLCNT PQRYHGLPVK LFDTSSCKDS APFQLLFIIN TSTLLTFILA 720
  721 VLLIHFEGWR ISFYWNVSVH RILGFKEIDA QGEQFEYTAY IIHAQKDRDW VWEHFSPMEE 780
  781 QDQSLKFCLE ERDFEAGVLG LEAIVNSIKR SRKIIFVITH HLLKDPLCRR FKVHHAVQQA 840
  841 IEQNLDSIIL IFLQNIPDYK LNHALCLRRG MFKSHCILNW PIQKERINAF HHKLQVALGS 900
  901 RNSAH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: gi|38454316, gi|...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: