Protein Overview: MMP14_RAT

General Information:
Name(s) found:	MMP14_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|47939003\|gb\|AAH72509.1\| Mmp14 protein [Rattus norvegicus] [NCBI NR] gi\|149063899\|gb\|EDM14169.1\| matrix metallopeptidase 14 (membrane-inserted), isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149063898\|gb\|EDM14168.1\| matrix metallopeptidase 14 (membrane-inserted), isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|146345458\|sp\|Q10739.2\|MMP14_RAT RecName: Full=Matrix metalloproteinase-14; Short=MMP-14; AltName: Full=Membrane-type matrix metalloproteinase 1; Short=MT-MMP 1; Short=MTMMP1; AltName: Full=Membrane-type-1 matrix metalloproteinase; Short=MT1-MMP; Short= [NCBI NR] gi\|13591995\|ref\|NP_112318.1\| matrix metalloproteinase 14 (membrane-inserted) [Rattus norvegicus] [NCBI NR] gi\|1001927\|emb\|CAA62897.1\| membrane-type metalloproteinase [Rattus norvegicus] [NCBI NR] Matrix metalloproteinase-14 OS=Rattus norvegicus GN=Mmp14 PE=2 SV=2 [Swiss-Prot] matrix metalloproteinase 14, membrane-inserted; membrane type 1-matrix metalloproteinase [HMR_022704-rand.fasta] matrix metalloproteinase 14 (membrane-inserted) [Rattus norvegicus]gi\|47939003\|gb\|AAH72509.1\| Mmp14 protein [Rattus norvegicus]gi\|1001927\|emb\|CAA62897.1\| membrane-type metalloproteinase [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Mmp14 protein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031056) matrix metalloproteinase 14, membrane-inserted [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] matrix metalloproteinase 14 (membrane-inserted) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Matrix metalloproteinase-14 precursor (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MT-MMP) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] matrix metallopeptidase 14 (membrane-inserted), isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] membrane-type metalloproteinase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Mmp14 protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Mmp14 Matrix metalloproteinase-14 [rat-ipi-250309-contam.fasta] matrix metalloproteinase-14 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Matrix metalloproteinase-14 OS=Rattus norvegicus GN=Mmp14 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	582 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA] melanosome [IEA] membrane [IEA] integral to membrane [IEA] extracellular matrix [IEA]
Biological Process:	astrocyte cell migration [IEP] response to estrogen stimulus [IEP] metabolic process [IEA] response to organic cyclic substance [IEP] branching morphogenesis of a tube [UNKNOWN][IEA] response to hormone stimulus [IDA] ovarian follicle development [IEP] response to mechanical stimulus [IEP] tissue remodeling [IDA] negative regulation of focal adhesion assembly [IDA] response to oxidative stress [IEP] zymogen activation [UNKNOWN][IEA] response to hypoxia [IEP] ossification [IEP] angiogenesis [IEP] proteolysis [IEA] endothelial cell proliferation [IEP] cell migration [UNKNOWN][IEA] lung development [UNKNOWN][IEA]
Molecular Function:	transcription factor activity [IEA] zinc ion binding [IEA] peptidase activator activity [IMP] protein binding [UNKNOWN][IEA] calcium ion binding [IEA] peptidase activity [IEA] metalloendopeptidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPAPRPSRS LLLPLLTLGT TLASLGWAQS SNFSPEAWLQ QYGYLPPGDL RTHTQRSPQS  60
   61 LSAAIAAMQR FYGLQVTGKA DSDTMKAMRR PRCGVPDKFG TEIKANVRRK RYAIQGLKWQ 120
  121 HNEITFCIQN YTPKVGEYAT FEAIRKAFRV WESATPLRFR EVPYAYIREG HEKQADIMIL 180
  181 FAEGFHGDST PFDGEGGFLA HAYFPGPNIG GDTHFDSAEP WTVQNEDLNG NDIFLVAVHE 240
  241 LGHALGLEHS NDPSAIMAPF YQWMDTENFV LPDDDRRGIQ QLYGSKSGSP TKMPPQPRTT 300
  301 SRPSVPDKPR NPTYGPNICD GNFDTVAMLR GEMFVFKERW FWRVRNNQVM DGYPMPIGQF 360
  361 WRGLPASINT AYERKDGKFV FFKGDKHWVF DEASLEPGYP KHIKELGRGL PTDKIDAALF 420
  421 WMPNGKTYFF RGNKYYRFNE EFRAVDSEYP KNIKVWEGIP ESPRGSFMGS DEVFTYFYKG 480
  481 NKYWKFNNQK LKVEPGYPKS ALRDWMGCPS GGRPDEGTEE ETEVIIIEVD EEGSGAVSAA 540
  541 AVVLPVLLLL LVLAVGLAVF FFRRHGTPKR LLYCQRSLLD KV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: MMP14_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: