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Protein Overview: HS71B_RAT, HS71A_RAT

General Information:
Name(s) found: HS71B_RAT [Swiss-Prot]
HS71A_RAT [Swiss-Prot]
Description(s) found:
Found 27 descriptions.
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  • Heat shock 70 kDa protein 1B OS=Rattus norvegicus GN=Hspa1a PE=2 SV=1 [Swiss-Prot]
  • Heat shock 70 kDa protein 1A OS=Rattus norvegicus GN=Hspa1a PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 641 amino acids

    Gene Ontology:
    Cellular Component: nuclear speck [UNKNOWN][ISS]
    protein complex [IDA]
    cytoplasmic part [UNKNOWN]
    intracellular [UNKNOWN]
    nucleus [UNKNOWN][IDA][ISS]
    perinuclear region of cytoplasm [UNKNOWN][ISS]
    ribonucleoprotein complex [UNKNOWN]
    cytoplasm [UNKNOWN][ISS]
    mitochondrion [UNKNOWN]
    cytosol [IDA]
    inclusion body [UNKNOWN]
    basolateral plasma membrane [IDA]
    apical plasma membrane [IDA]
    Biological Process: DNA repair [UNKNOWN]
    [NOT]negative regulation of myeloid cell apoptosis [IDA]
    negative regulation of cell proliferation [UNKNOWN][ISS]
    negative regulation of vasoconstriction [IMP]
    telomere maintenance [UNKNOWN]
    mRNA catabolic process [UNKNOWN][ISS]
    defense response [IDA]
    protein refolding [UNKNOWN]
    response to unfolded protein [UNKNOWN][IMP][ISS]
    negative regulation of inclusion body assembly [UNKNOWN]
    response to heat [UNKNOWN]
    anti-apoptosis [UNKNOWN]
    negative regulation of cell growth [UNKNOWN][ISS]
    negative regulation of apoptosis [IDA]
    negative regulation of caspase activity [UNKNOWN][IDA]
    positive regulation of T cell mediated cytotoxicity [IDA]
    Molecular Function: nucleotide binding [IEA]
    NF-kappaB binding [IPI]
    ATP binding [IEA]
    protein binding [UNKNOWN][IPI]
    ubiquitin protein ligase binding [UNKNOWN]
    protein binding involved in protein folding [UNKNOWN]
    protein N-terminus binding [UNKNOWN]
    protease binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKTAIGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL IGDAAKNQVA  60
   61 LNPQNTVFDA KRLIGRKFGD PVVQSDMKHW PFQVVNDGDK PKVQVNYKGE NRSFYPEEIS 120
  121 SMVLTKMKEI AEAYLGHPVT NAVITVPAYF NDSQRQATKD AGVIAGLNVL RIINEPTAAA 180
  181 IAYGLDRTGK GERNVLIFDL GGGTFDVSIL TIDDGIFEVK ATAGDTHLGG EDFDNRLVSH 240
  241 FVEEFKRKHK KDISQNKRAV RRLRTACERA KRTLSSSTQA SLEIDSLFEG IDFYTSITRA 300
  301 RFEELCSDLF RGTLEPVEKA LRDAKLDKAQ IHDLVLVGGS TRIPKVQKLL QDFFNGRDLN 360
  361 KSINPDEAVA YGAAVQAAIL MGDKSENVQD LLLLDVAPLS LGLETAGGVM TALIKRNSTI 420
  421 PTKQTQTFTT YSDNQPGVLI QVYEGERAMT RDNNLLGRFE LSGIPPAPRG VPQIEVTFDI 480
  481 DANGILNVTA TDKSTGKANK ITITNDKGRL SKEEIERMVQ EAERYKAEDE VQRERVAAKN 540
  541 ALESYAFNMK SAVEDEGLKG KISEADKKKV LDKCQEVISW LDSNTLAEKE EFVHKREELE 600
  601 RVCNPIISGL YQGAGAPGAG GFGAQAPKGG SGSGPTIEEV D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle