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Protein Overview: Rpn12R-PA

General Information:
Name(s) found: Rpn12R-PA / FBpp0075422 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\Rpn12R (CG11552, FBgn0036465). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:15034726..15035670. It has the cytological map location 71B2. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: proteolysis. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 262 amino acids

    Gene Ontology:
    Cellular Component: proteasome regulatory particle [ISS]
    Biological Process: proteolysis [ISS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNLYTELKN EWSKHAPNLT HCSRLLDGFK LELVRSNFGT IQTASSSKQK DQLIKSREML  60
   61 EIAVEHSITI KDYAAFERYM AQLNTYYYDY DKYLESSKHM YKFMGLNLLY MLATNRLADF 120
  121 HIELERLPTA LLLHDSFIQP VLALENYYME GRYNKILQAK KSMPSEIYSN FMDILVNTAR 180
  181 EEIASCMEKS YLKMAPKLAA QRLGLRPGSK ELFELATKRQ WCLDEEGNYD YAGLHTRPME 240
  241 KVPAKDIATH NLTYAQELEK IV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..262] FFAS03 1.56 Crystal Structure of Human eIF3k

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.76236644111948 bayes_pls_golite062009
  • hydrolase activity
    		•  2.62777210765927 bayes_pls_golite062009
  • protein binding
    		•  1.5114863464349 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.48815906385664 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.08079130332447 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.06350696248374 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.700922242779288 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.37240198519167 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.224432853777564 bayes_pls_golite062009
  • DNA binding
    		•  0.180353635969032 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.147335771550418 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.142921675412538 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.124542865343065 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle