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View Structure Prediction Details

Protein: Rpn12R-PA
Organism: Drosophila melanogaster
Length: 262 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rpn12R-PA.

Description E-value Query
Range
Subject
Range
gi|34855658, gi|... - gi|34855658|ref|XP_214888.2| PREDICTED: similar to proteasome 26S non-ATPase subunit 8 [Rattus norve...
276.0 [0..2] [262..95]
gi|57036591 - gi|57036591|ref|XP_533681.1| PREDICTED: similar to 26S proteasome non-ATPase regulatory subunit 8 (2...
274.0 [0..2] [262..93]
gi|74204612 - gi|74204612|dbj|BAE35376.1| unnamed protein product [Mus musculus]
270.0 [0..2] [262..31]
gi|40787635 - gi|40787635|gb|AAH65006.1| Unknown (protein for IMAGE:6055235) [Homo sapiens]
269.0 [0..2] [262..22]

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Predicted Domain #1
Region A:
Residues: [1-262]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNLYTELKN EWSKHAPNLT HCSRLLDGFK LELVRSNFGT IQTASSSKQK DQLIKSREML  60
   61 EIAVEHSITI KDYAAFERYM AQLNTYYYDY DKYLESSKHM YKFMGLNLLY MLATNRLADF 120
  121 HIELERLPTA LLLHDSFIQP VLALENYYME GRYNKILQAK KSMPSEIYSN FMDILVNTAR 180
  181 EEIASCMEKS YLKMAPKLAA QRLGLRPGSK ELFELATKRQ WCLDEEGNYD YAGLHTRPME 240
  241 KVPAKDIATH NLTYAQELEK IV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.56
Match: 1rz4A
Description: Crystal Structure of Human eIF3k
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.76236644111948 bayes_pls_golite062009
hydrolase activity 2.62777210765927 bayes_pls_golite062009
protein binding 1.5114863464349 bayes_pls_golite062009
structural constituent of ribosome 1.48815906385664 bayes_pls_golite062009
nucleic acid binding 1.08079130332447 bayes_pls_golite062009
sequence-specific DNA binding 1.06350696248374 bayes_pls_golite062009
transcription repressor activity 0.700922242779288 bayes_pls_golite062009
cytoskeletal protein binding 0.37240198519167 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.224432853777564 bayes_pls_golite062009
DNA binding 0.180353635969032 bayes_pls_golite062009
transcription regulator activity 0.147335771550418 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.142921675412538 bayes_pls_golite062009
small conjugating protein ligase activity 0.124542865343065 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle