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Protein Overview: FBpp0306393, e(y...

General Information:
Name(s) found: FBpp0306396 [FlyBase]
FBpp0306393 [FlyBase]
e(y)3-PA / FBpp0074531 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • type=protein; loc=X:complement(19522132..19522796,19522936..19523124,19523183..19523393,19523549..19523846,19523907..19524182,19524270..19524719,19524778..19524933,19524999..19525099,19526670..19526938,19527003..19528104,19528167..19530470); ID=FBpp0306396; name=e(y)3-PE; parent=FBgn0087008,FBtr0334281; dbxref=FlyBase:FBpp0306396,FlyBase_Annotation_IDs:CG12238-PE,REFSEQ:NP_001259721,GB_protein:AGB95561; MD5=a33428a3dd08b945c98bf11e48819789; length=2006; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:complement(19522132..19522796,19522936..19523124,19523183..19523393,19523549..19523846,19523907..19524182,19524270..19524719,19524778..19524933,19524999..19525099,19526670..19526938,19527003..19528104,19528167..19530470); ID=FBpp0306393; name=e(y)3-PB; parent=FBgn0087008,FBtr0334278; dbxref=FlyBase:FBpp0306393,FlyBase_Annotation_IDs:CG12238-PB,REFSEQ:NP_001259718,GB_protein:AGB95558; MD5=a33428a3dd08b945c98bf11e48819789; length=2006; release=r5.56; species=Dmel; [FlyBase]
  • The gene enhancer of yellow 3 is referred to in FlyBase by the symbol Dmel\e(y)3 (CG12238, FBgn0087008). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19521982..19532385. It has the cytological map location 18D8-18D11. There is experimental evidence that it has the molecular function</span>: transcription regulator activity; chromatin binding. There is experimental evidence that it is involved in the biological process</span>: gene silencing; oogenesis; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent. 35 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord commissure; embryonic head; embryonic midgut; embryonic Malpighian tubule; femur; macrochaeta; wing. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2006 amino acids

    Gene Ontology:
    Cellular Component: polytene chromosome [IDA]
    heterochromatin [IDA]
    nucleus [IDA]
    euchromatin [IDA]
    Biological Process: gene silencing [IMP]
    negative regulation of transcription, DNA-dependent [IMP]
    positive regulation of transcription, DNA-dependent [IMP]
    oogenesis [IMP]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IEA]
    transcription regulator activity [IMP]
    chromatin binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDLRQQQMV AATSSSGSES GTAVESAAAT STAGSAGAAG RPQSNCSANS NAKSVAASST  60
   61 SEEEQRVSST SSPAQRDQQL NADRDREQEP EPQQQQQREE ALQHQHNQPG HITSTTASPP 120
  121 PTLPPPTTPC DDAPSTTGAS ASASSASGEA PSAASAAGAA GGPMAATALE VESEERDGHK 180
  181 IILKLSKHAN PNSNANESQP GGDERRVEPL RIQLPCGGAE GGLVAKQQDA FDADASSCSS 240
  241 SCAEDEVATT LGQQLRNTPH IVPKLTIRAA NERRVGSVVP KLTIKLPENP AASGSNSNSG 300
  301 SCSAAVSGAQ SAMPAKNDAH LSSLSPASAS SSSASSSSSS SSSSSLAEMQ TVPKLMIKTT 360
  361 LAGSSCISSS EELPQQQQQI PKLTIKTGGG GQEHVHTVIM THDLNNAQSI PKLTIKTKSI 420
  421 EMIEDEQAAK LEQQLQPLPK LTIKNLCSPK HKVRAVLEEK PPTAASKLAI PKPTPNPTPA 480
  481 PMTNGGESNS SSQEFCGFSD PDADIAAPAS DDVRRNSDDM VIDDSLSKEH DPKIFHNLPP 540
  541 MPASNGIASG GSKASKASKS AQSQHNVVDM VDLTSSPSPG SSPTHVPNNF TGRISPKGLL 600
  601 IDCLRMQTAI GCYVPEEADS RVRPAASPNS NILLSQLTAP AKSFTTTTPK SKSSKYPQLT 660
  661 ERLMANGSGT GGGSVIAAES EAVVGPLPAA NPAQSIIESI EILDTPDGSP RVAYMDEDSN 720
  721 PMLNKHLQTI HKLAMDHGVE QRMDTQDNNN ENHLKRTNSE GNESPSSRLP PSKQRRLDND 780
  781 ENDQQTQNCH DPARKCSESL QALPPSHRSR KQKHERILNT DLEGSLFPPT QQQSISTPDQ 840
  841 NGALSSEVEG EDAKAQDPLE PATPQPPPVA TPAGTGKKRG RPKRIQNQSS PDGGGAVTPK 900
  901 PGTPQEEANS AVKSRRVQLL RKRLAIDMVS VGQEQADMKA KEKESSVGVP NARVEDGLAE 960
  961 TLESPKTRDH RPLRATRRTT TSTNTNLQPT PKSTRKRQSK ASVQQSQLPP PTMAQFGSSE1020
 1021 SESNNNNNSS ISFALSAQID LTMCSSSSST SSGAAANQQV IGGSGSSSML PPTTILSSSD1080
 1081 PLPDVIFQPN DFSSIMATQQ LRSSRPSSIS CGSTGGSQPD CHDEDNYTSA LDNSGDETAL1140
 1141 PMPPTRGRGR GRRSRGGRGR GSSSVDRAVS VGGTASTTPA TQPRAPRMSR GASAVAKAIA1200
 1201 MSRPRCVGGL KHQPDPERLK GLFSPSPQVF EEDTRMSADL SNSNQSMASL MEPPLTPQKQ1260
 1261 PDFLNNEESQ SSMVSNVSMM DSNQGQSADA ILGSALKRPK KKKMETCVAE DTDYSASSIA1320
 1321 EYDWPPPKGC CPSKNRDTFM IQEQVALYLG ITSFKRKYPD LPRRSVDMEE RNWLQEKGLV1380
 1381 SEKLCDLGIT AVWASDILDI MYADFFDKYE EYKEYIRRKH LREIEAKQKA LGLTVGAGRG1440
 1441 LQARDRAMLS ATKWNAYFNK SRKDERQSCM DLQTFTINQP QPRTAPTCTR LERSTSDLIR1500
 1501 AVAEEANIPA PPNLLPPRDY DEAFRNSDYA YPLTVVPDQF SMAYRQFEPA ELRAYPLDTA1560
 1561 LDKPPTDLMA QLLQAKSEAV GSDEIKTSAP APKDLGQEQS AIKSVTVTAP VRRSRRSTRQ1620
 1621 QTDKVRTASS SSTSSAQSVS SASSGNGSSS DTESGDESDF SSTSSCSSST GASSGAGSED1680
 1681 EDGNECSSSV RLSTCGVCLR SQHRNARDMP EAFIRCYTCR KRVHPSCVDM PPRMVGRVRN1740
 1741 YNWQCAGCKC CIKCRSSQRP GKMLYCEQCD RGYHIYCLGL RTVPDGRWSC ERCCFCMRCG1800
 1801 ATKPEGLPQV AALSQASGGP SANGDRSKAA RNKRLKWVHE YRIDHVTKIR EHAAMFCVPC1860
 1861 ARNKPAKRQS AAGAAGAAAV TPVLEATSAQ TDDSPMPSPG LTTNGGRALS PTAALSPKAA1920
 1921 VPVASLPPVL EATTVTTNIA GTIGRRQAGN AVNITTMQCS SSSSSNFSGN GVTEDAANVT1980
 1981 ATGTATAAAG APAATPIGIA PPPVVA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] deduced N/A No confident structure predictions are available.
    2 View Details [89..250] deduced N/A No confident structure predictions are available.
    3 View Details [251..458] deduced N/A No confident structure predictions are available.
    4 View Details [459..640] MSA 1.115986 View MSA. No confident structure predictions are available.
    5 View Details [641..768] deduced N/A No confident structure predictions are available.
    6 View Details [769..902] deduced N/A No confident structure predictions are available.
    7 View Details [903..1027] MSA 1.123987 View MSA. No confident structure predictions are available.
    8 View Details [1028..1087] deduced N/A No confident structure predictions are available.
    9 View Details [1088..1284] MSA 3.109984 View MSA. No confident structure predictions are available.
    10 View Details [1285..1353] deduced N/A No confident structure predictions are available.
    11 View Details [1354..1583] deduced N/A No confident structure predictions are available.
    12 View Details [1584..1726] PSI-BLAST 5.045757 Solution structure of tandem repeat of the zf-C2H2 domains of human zinc finger protein 297B
    13 View Details [1727..1864] PSI-BLAST 20.30103 No description for 2ysmA was found.
    14 View Details [1865..2006] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.
    11 No functions predicted.
    12
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription activator activity
    		•  3.52873291636993 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.27542149084008 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.53101891154822 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.31369346002275 bayes_pls_golite062009
  • protein binding
    		•  2.05530362750351 bayes_pls_golite062009
  • chromatin binding
    		•  1.53640935908107 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.34049786451995 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.0497955246512 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.10146306852499 bayes_pls_golite062009
    13 No functions predicted.
    14 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.70

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle