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Protein Overview: gi|74876832, gi|...

General Information:
Name(s) found: gi|74876832 [NCBI NR]
gi|45551421 [NCBI NR]
gi|45446811 [NCBI NR]
Description(s) found:
Found 10 descriptions.
SHOW ALL
  • gi|74876832|sp|Q7KVW5.1|KCNN3_DROME RecName: Full=Small conductance calcium-activated potassium channel protein; AltName: Full=Protein SK; AltName: Full=dSK [NCBI NR]
  • gi|45551421|ref|NP_726986.2| small conductance calcium-activated potassium channel, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|45446811|gb|AAN09136.2| small conductance calcium-activated potassium channel, isoform C [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 924 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    Biological Process: potassium ion transport [ISS]
    Molecular Function: calcium-activated potassium channel activity [ISS]
    calmodulin binding [IEA]
    small conductance calcium-activated potassium channel activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIQKLNDTT NSGYVSSEET DSLLVSSSNP SKGGGRTALL RQVKSNSTNG PTTGASTSSS  60
   61 GSVSGGGGGS GSGGGSASGS AAGASKPTLM RQDRTSTYLT SPQQSQHARM GSEESMRGGA 120
  121 SGAAGHDEDV EQGLVRSSIV PDIEVHEEDQ EQHSQQLNAT TMATMTNNQQ QQQPTISIMN 180
  181 LSLKPGDSHS HSSSPGSHPN LGTSSYQNLA SSIPPSVPSR CRACRNCSRR ASTTPTTLID 240
  241 RSASRDSVKS AFQQGNLSGS MAICISNSAL PQQQQLQQQY HLQQQQQQHY QLQQHHLHQQ 300
  301 QLQQSQQQVP PVLITSSPTN GSRIIRQSSQ PESSSTAICC GPHSACVGHA HSHSHTVPNV 360
  361 SLKQLRESSG DGIAGIAADS LRINGGMRPF KQLRKPASTL SIPGSMKTPS IANREQISSG 420
  421 CNEEAAEALV GIHSDYPRYM EERALTGGNT SRKPSTNSAK HKPNVGYRLG KRKALFEKRK 480
  481 RISDYALVMG MFGIIVMVIE NELSSAGVYT KASFYSTALK TLISVSTVIL LGLIVAYHAL 540
  541 EVQLFMIDNC ADDWRIAMTW QRISQIGLEL FICAIHPIPG EYYFQWTTKL ANKNKTIGTE 600
  601 MVPYDVALSL PMFLRLYLIC RVMLLHSKLF TDASSRSIGA LNRINFNTRF VLKTLMTICP 660
  661 GTVLLVFMVS LWIIASWTLR QCERFHDEEH ANLLNSMWLT AITFLCVGYG DIVPNTYCGR 720
  721 GITLTCGMVG AGCTALLVAV VSRKLELTRA EKHVHNFMMD TQLTKRLKNA AANVLRETWL 780
  781 IYKHTRLVKR VNPGRVRTHQ RKFLLAIYAL RKVKMDQRKL MDNANTITDM AKTQNTVYEI 840
  841 ISDMSSRQDA IEERLTNLED KMQSIQEHME SLPDLLSRCL TQHQERIEQR RNFLHPDTAA 900
  901 VAPIQAPTPQ SMFNAAPMLF PHSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..464] PSI-BLAST 7.0 No description for 1y0fA was found.
    2 View Details [465..765] PSI-BLAST 14.69897 Potassium channel KVAP
    3 View Details [766..820] PSI-BLAST 23.69897 Small-conductance potassium channel
    4 View Details [821..924] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • voltage-gated potassium channel activity
    		•  12.0716262326447 bayes_pls_golite062009
  • potassium channel activity
    		•  12.0564503263181 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  11.2479281243224 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  11.0164314117387 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  10.9923023836994 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  9.85051068330727 bayes_pls_golite062009
  • cation channel activity
    		•  9.62064031772276 bayes_pls_golite062009
  • ion channel activity
    		•  8.91395130684665 bayes_pls_golite062009
  • gated channel activity
    		•  8.84587381436962 bayes_pls_golite062009
  • channel activity
    		•  8.68489845295557 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  8.68489845295557 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  8.67927944890782 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  5.74511802205447 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  5.74511802205447 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  5.13805155650973 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  5.0997110076666 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.04374327766634 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.64120459994573 bayes_pls_golite062009
  • transporter activity
    		•  2.93091397928047 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.82224868778929 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.79688978937497 bayes_pls_golite062009
    3
    Term Confidence Notes
  • potassium channel activity
    		•  12.9154216859515 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  10.690117627191 bayes_pls_golite062009
  • cation channel activity
    		•  10.4729582700993 bayes_pls_golite062009
  • ion channel activity
    		•  9.76420146980976 bayes_pls_golite062009
  • gated channel activity
    		•  9.69845089208228 bayes_pls_golite062009
  • channel activity
    		•  9.53251272468341 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  9.53251272468341 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  9.52766364291262 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  5.94944590079392 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.84582254185274 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  5.42471865207378 bayes_pls_golite062009
  • calcium-activated potassium channel activity
    		•  4.85096783740785 bayes_pls_golite062009
  • ion gated channel activity
    		•  3.66857233866209 bayes_pls_golite062009
  • transporter activity
    		•  3.65156094985283 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.56349914685586 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5594499564237 bayes_pls_golite062009
  • small conductance calcium-activated potassium channel activity
    		•  3.44162773824006 bayes_pls_golite062009
  • calcium activated cation channel activity
    		•  3.35031790098165 bayes_pls_golite062009
  • protein binding
    		•  1.61033690476624 bayes_pls_golite062009
  • binding
    		•  1.32969330984971 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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