Protein Overview: RTN4_RAT

General Information:
Name(s) found:	RTN4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6822247\|emb\|CAB71027.1\| Nogo-A protein [Rattus norvegicus] [NCBI NR] gi\|17367410\|sp\|Q9JK11.1\|RTN4_RAT RecName: Full=Reticulon-4; AltName: Full=Neurite outgrowth inhibitor; Short=Nogo protein; AltName: Full=Foocen; AltName: Full=Glut4 vesicle 20 kDa protein [NCBI NR] gi\|13929188\|ref\|NP_114019.1\| reticulon 4 [Rattus norvegicus] [NCBI NR] Reticulon-4 OS=Rattus norvegicus GN=Rtn4 PE=1 SV=1 [Swiss-Prot] reticulon 4; foocen; GLUT4 vesicle 20kDa protein; Nogo-A; neurite outgrowth inhibitor; NI-220/250 [HMR_022704-rand.fasta] reticulon 4; foocen; neurite outgrowth inhibitor; GLUT4 vesicle 20kDa protein; Nogo-A; NI-220/250 [071204_hmrz_cont.fasta] reticulon 4 [Rattus norvegicus]gi\|6822247\|emb\|CAB71027.1\| Nogo-A protein [Rattus norvegicus]gi\|17367410\|sp\|Q9JK11\|RTN4_RAT Reticulon 4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Glut4 vesicle 20 kDa protein) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Reticulon-4 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031831) Nogo-A; foocen [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform 1 of Reticulon 4 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] reticulon 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Glut4 vesicle 20 kDa protein) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Nogo-A protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF RETICULON 4 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Rtn4 Isoform 1 of Reticulon-4 [rat-ipi-250309-contam.fasta] Isoform 1 of Reticulon-4 OS=Rattus norvegicus GN=Rtn4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1163 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [UNKNOWN][ISS] endoplasmic reticulum membrane [IEA] myelin sheath [IDA] cytoplasm [IDA] integral to membrane [TAS] integral to endoplasmic reticulum membrane [UNKNOWN][IDA] endoplasmic reticulum [UNKNOWN][IDA][IEA] neuronal cell body [UNKNOWN][IDA] protein complex [IDA] cell projection [UNKNOWN] neuron projection [IDA] plasma membrane [UNKNOWN][IDA]
Biological Process:	oligodendrocyte differentiation [IEP] nervous system development [UNKNOWN][IEA] negative regulation of neuron differentiation [IDA] positive regulation of glial cell differentiation [IDA] regulation of axon regeneration [IDA] aging [IEP] olfactory nerve development [IEP] negative regulation of axonogenesis [UNKNOWN][IDA][IMP] angiogenesis [UNKNOWN][IEA] negative regulation of neuron projection development [IDA] negative regulation of axon extension [UNKNOWN][ISS] regulation of axonogenesis [UNKNOWN] negative regulation of neuron projection regeneration [IMP] response to activity [IEP] regulation of cell migration [UNKNOWN][IEA] positive regulation of dopamine secretion [IMP] regulation of sensory perception of pain [IDA] negative regulation of anti-apoptosis [UNKNOWN][ISS]
Molecular Function:	protein binding [UNKNOWN][IPI] protein complex binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDIDQSSLV SSSTDSPPRP PPAFKYQFVT EPEDEEDEEE EEDEEEDDED LEELEVLERK  60
   61 PAAGLSAAAV PPAAAAPLLD FSSDSVPPAP RGPLPAAPPA APERQPSWER SPAAPAPSLP 120
  121 PAAAVLPSKL PEDDEPPARP PPPPPAGASP LAEPAAPPST PAAPKRRGSG SVDETLFALP 180
  181 AASEPVIPSS AEKIMDLMEQ PGNTVSSGQE DFPSVLLETA ASLPSLSPLS TVSFKEHGYL 240
  241 GNLSAVSSSE GTIEETLNEA SKELPERATN PFVNRDLAEF SELEYSEMGS SFKGSPKGES 300
  301 AILVENTKEE VIVRSKDKED LVCSAALHSP QESPVGKEDR VVSPEKTMDI FNEMQMSVVA 360
  361 PVREEYADFK PFEQAWEVKD TYEGSRDVLA ARANVESKVD RKCLEDSLEQ KSLGKDSEGR 420
  421 NEDASFPSTP EPVKDSSRAY ITCASFTSAT ESTTANTFPL LEDHTSENKT DEKKIEERKA 480
  481 QIITEKTSPK TSNPFLVAVQ DSEADYVTTD TLSKVTEAAV SNMPEGLTPD LVQEACESEL 540
  541 NEATGTKIAY ETKVDLVQTS EAIQESLYPT AQLCPSFEEA EATPSPVLPD IVMEAPLNSL 600
  601 LPSAGASVVQ PSVSPLEAPP PVSYDSIKLE PENPPPYEEA MNVALKALGT KEGIKEPESF 660
  661 NAAVQETEAP YISIACDLIK ETKLSTEPSP DFSNYSEIAK FEKSVPEHAE LVEDSSPESE 720
  721 PVDLFSDDSI PEVPQTQEEA VMLMKESLTE VSETVAQHKE ERLSASPQEL GKPYLESFQP 780
  781 NLHSTKDAAS NDIPTLTKKE KISLQMEEFN TAIYSNDDLL SSKEDKIKES ETFSDSSPIE 840
  841 IIDEFPTFVS AKDDSPKLAK EYTDLEVSDK SEIANIQSGA DSLPCLELPC DLSFKNIYPK 900
  901 DEVHVSDEFS ENRSSVSKAS ISPSNVSALE PQTEMGSIVK SKSLTKEAEK KLPSDTEKED 960
  961 RSLSAVLSAE LSKTSVVDLL YWRDIKKTGV VFGASLFLLL SLTVFSIVSV TAYIALALLS1020
 1021 VTISFRIYKG VIQAIQKSDE GHPFRAYLES EVAISEELVQ KYSNSALGHV NSTIKELRRL1080
 1081 FLVDDLVDSL KFAVLMWVFT YVGALFNGLT LLILALISLF SIPVIYERHQ VQIDHYLGLA1140
 1141 NKSVKDAMAK IQAKIPGLKR KAD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: RTN4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: