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The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. The process whereby neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. The process by which glial cells are generated. This includes the production of glial progenitors and their differentiation into mature glia. Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation. The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte differentiation. The process whereby a relatively unspecialized cell acquires the specialized features of a glial cell. The process whereby the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: oligodendrocyte differentiation
Acc: GO:0048709
Aspect: Biological Process
Desc: The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
Proteins in PDR annotated with:
   This term: 30 [Search]
   Term or descendants: 76 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048709 - oligodendrocyte differentiation (interactive image map)
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