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Protein Overview: Ranbp16-PB, FBpp...

General Information:
Name(s) found: FBpp0309272 [FlyBase]
Ranbp16-PB / FBpp0089083 [FlyBase]
Description(s) found:
Found 30 descriptions.
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  • type=protein; loc=X:complement(15822893..15822963,15823374..15823435,15823505..15823624,15823691..15823830,15823887..15823948,15824014..15824091,15824150..15824288,15824356..15824915,15824975..15825267,15825340..15826019,15826077..15826223,15826279..15826494,15826555..15826654,15826883..15827112,15827176..15827571,15827634..15827636); ID=FBpp0309272; name=Ranbp16-PH; parent=FBgn0053180,FBtr0340311; dbxref=FlyBase:FBpp0309272,FlyBase_Annotation_IDs:CG33180-PH; MD5=6d853bfd339cb8476a5c2c82543abe25; length=1098; release=r5.56; species=Dmel; [FlyBase]
  • The gene Ranbp16 is referred to in FlyBase by the symbol Dmel\Ranbp16 (CG33180, FBgn0053180). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15822740..15827687. It has the cytological map location 14A1. It is reported to have molecular function</span>: Ran GTPase binding; nuclear export signal receptor activity. It is reported to be involved in the biological process</span>: protein export from nucleus. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1098 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    cytoplasm [NAS]
    nuclear pore [NAS]
    Biological Process: protein export from nucleus [NAS]
    intracellular protein transport [IEA]
    Molecular Function: protein transporter activity [IEA]
    binding [IEA]
    Ran GTPase binding [NAS]
    nuclear export signal receptor activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIQQLEVLC KQLYEATDIR IRSEAEKALV TFVSSQDALP KCQLLLQRAD SSYAQLLAAS  60
   61 TLTKLIQGLS LQERIDIRSY ALNYLATVPN LQHFVVQALV SLLAKLTKYG WFDSYKEEMV 120
  121 FQNLLEDVKK FLQGSVEHCT IGVQILSQLV CEMNSVVEMD VQVSFSKMRK IATSFRDQQL 180
  181 LETFLLSCSL LVSARDNSKN ISFMDESQQA LISHVLRLTK NCLSFDFIGS STDESADDMN 240
  241 NVQIPTAWRP AFLDSNTLKL FFDLYQILPN GLASYSISCL VQITSVRRSL FNNSERTKFL 300
  301 THLVEGVKDI LTTLHGLSDP DNYHEFCRLL ARLKSNYQLG ELIAVPCYPE AIQLIAKFTV 360
  361 ESLHLWLFAP NSVHYLLTLW QRMVASVPYV KSPDPHLLGT YTPEVIKAYI ESRLDAVPVI 420
  421 IRDNLDDPLD DFCMVQQQLE QLSVIERCEY NKTCNLLVQH FDQKAREYEN LLQTPNANSI 480
  481 DITIHELQLT WLVYIIGSAI VGRLTVATSD EHDTMDAELV IRVLQLMTLT DARLPQAGCE 540
  541 KLELAILSFL DQVRKMHSSE QAQKANLNKR LSEVFGLTDE QMLLSFINRK IITNLKFWGR 600
  601 SESIITKTLM LLSELSVHFN SVRKLARLEE VQFMLTHHTS EHFPFLGTNS SLSEMRCRTM 660
  661 FYTSLGRLLM FDLGEDEERF YNFLEPLTNQ FESLGSVMMD NNIFSNEEAK KVIIGLARDL 720
  721 RGLALPLNAR IQYTMLFEWL YYADYLPILL RAMDLWAHDP AVTTPILKLF AELVHCRTQR 780
  781 LAGNVSSPMG ILLFREASKL ICIYGNRILH QEVPRERLYP MRLKGIAICF LILKNSLGGN 840
  841 YVNCGVFKLY GDDTLDSVLN IIAKLILTIE QRDLIEYPKL STAYYNLLNC LSQDHVSYLA 900
  901 ALEPAAFVYI LKSLTKGLAA LDSATYISCC TILDSIVSYI FKQLQMKVST FPNKKLRSLN 960
  961 QENVQFLKVV EMNSELLQSM MSSLLNNVLQ EDCRNQWSMS RPLLVLILLY EDYYRSLKDR1020
 1021 IICAQPIEKQ QTMAQWFDDL MVGIERNVSS KNKEKFTQNM STFRRDVVNL PKSTAAFSCD1080
 1081 RPMCDGGFEP SEPESSPH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..869] PSI-BLAST 5.0 Karyopherin beta2
    2 View Details [870..1098] PSI-BLAST 61.39794 Proteolytic fragment of CRM1 spanning six C-terminal HEAT repeats

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  4.58709163830613 bayes_pls_golite062009
  • nuclear export signal receptor activity
    		•  3.48172991171337 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.74547353635661 bayes_pls_golite062009
  • binding
    		•  2.61658111885029 bayes_pls_golite062009
  • transporter activity
    		•  2.48700774379895 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.26725422172281 bayes_pls_golite062009
  • protein binding
    		•  2.13529412360404 bayes_pls_golite062009
  • RNA binding
    		•  1.90646441530563 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.28481004323799 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  1.27627067567874 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.09652988954158 bayes_pls_golite062009
  • signal sequence binding
    		•  0.57106697498903 bayes_pls_golite062009
  • importin-alpha export receptor activity
    		•  0.259676026705859 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252495966234234 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.248585912061178 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.226380819487924 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.217517113570989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.178770060806735 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.175241020572885 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.174922130116569 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.169755106399802 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.100181463251306 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0635404099346928 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0548082069333885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.052195223119721 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0405268469927988 bayes_pls_golite062009
  • mRNA binding
    		•  0.0364755031177104 bayes_pls_golite062009
    2
    Term Confidence Notes
  • protein transporter activity
    		•  4.58709163830613 bayes_pls_golite062009
  • nuclear export signal receptor activity
    		•  3.48172991171337 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.74547353635661 bayes_pls_golite062009
  • binding
    		•  2.61658111885029 bayes_pls_golite062009
  • transporter activity
    		•  2.48700774379895 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.26725422172281 bayes_pls_golite062009
  • protein binding
    		•  2.13529412360404 bayes_pls_golite062009
  • RNA binding
    		•  1.90646441530563 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.28481004323799 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  1.27627067567874 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.09652988954158 bayes_pls_golite062009
  • signal sequence binding
    		•  0.57106697498903 bayes_pls_golite062009
  • importin-alpha export receptor activity
    		•  0.259676026705859 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252495966234234 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.248585912061178 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.226380819487924 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.217517113570989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.178770060806735 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.175241020572885 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.174922130116569 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.169755106399802 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.100181463251306 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0635404099346928 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0548082069333885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.052195223119721 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0405268469927988 bayes_pls_golite062009
  • mRNA binding
    		•  0.0364755031177104 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle