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Protein Overview: gi|157823263, gi...

General Information:
Name(s) found: gi|157823263 [NCBI NR]
gi|149019691 [NCBI NR]
Description(s) found:
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  • gi|157823263|ref|NP_001101797.1| protein kinase, DNA-activated, catalytic polypeptide [Rattus norvegicus] [NCBI NR]
  • gi|149019691|gb|EDL77839.1| protein kinase, DNA activated, catalytic polypeptide (predicted) [Rattus norvegicus] [NCBI NR]
  • protein kinase, DNA activated, catalytic polypeptide [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • protein kinase, DNA activated, catalytic polypeptide (predicted) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Protein kinase, DNA activated, catalytic polypeptide (Predicted) OS=Rattus norvegicus GN=Prkdc [011711_HMR.fasta]
  • Protein kinase, DNA activated, catalytic polypeptide (Predicted) OS=Rattus norvegicus GN=Prkdc_predicted PE=4 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
  • Protein kinase, DNA activated, catalytic polypeptide (Predicted) OS=Rattus norvegicus GN=Prkdc PE=4 SV=1 [Aridor_1205.fasta]
  • Protein kinase, DNA activated, catalytic polypeptide (Predicted) OS=Rattus norvegicus GN=Prkdc_predicted [120808_122_R_norvegicus.fasta]
    • Organism: Rattus norvegicus
    Length: 2098 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    transcription factor complex [UNKNOWN]
    nonhomologous end joining complex [UNKNOWN]
    DNA-dependent protein kinase-DNA ligase 4 complex [UNKNOWN]
    cellular_component [ND]
    nucleoplasm [UNKNOWN]
    Biological Process: biological_process [ND]
    germ cell programmed cell death [UNKNOWN]
    T cell differentiation in the thymus [UNKNOWN]
    T cell receptor V(D)J recombination [UNKNOWN]
    immunoglobulin V(D)J recombination [UNKNOWN]
    telomere maintenance [UNKNOWN]
    T cell lineage commitment [UNKNOWN]
    brain development [UNKNOWN]
    double-strand break repair via nonhomologous end joining [IEA]
    double-strand break repair [UNKNOWN]
    protein destabilization [UNKNOWN]
    cellular response to insulin stimulus [UNKNOWN]
    heart development [UNKNOWN]
    B cell lineage commitment [UNKNOWN]
    somitogenesis [UNKNOWN]
    pro-B cell differentiation [UNKNOWN]
    apoptosis [UNKNOWN]
    positive regulation of apoptosis [UNKNOWN]
    lymphocyte differentiation [UNKNOWN]
    response to gamma radiation [UNKNOWN]
    positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN]
    peptidyl-serine phosphorylation [UNKNOWN]
    Molecular Function: DNA binding [IEA]
    DNA-dependent protein kinase activity [UNKNOWN][IEA]
    ATP binding [IEA]
    protein binding [UNKNOWN]
    transcription factor binding [UNKNOWN]
    protein serine/threonine kinase activity [UNKNOWN]
    binding [IEA]
    phosphotransferase activity, alcohol group as acceptor [IEA]
    kinase activity [IEA]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFTTTLLVT FPEDCKLLEK DLCNTKLMKV LVKMLCEPLS IGFNIGDVQV MNHLPSICVN  60
   61 LLKALRKSPY RDKLETHLKE KVTAQSVEEL CAINLCSSAA CQERTKLLSL LSACKQLHKA 120
  121 GFSHIISASQ STALNHSIGM RLLSLVYNGI APAQEKQYLQ SLDPSCKSLA SGLLELAFAF 180
  181 GGLCEHLVSL LLNSSMLSTQ YLGSSQRNIS FSHGEYFYSL FPEVINTELL KSLDVTVSRL 240
  241 LESSSDNPKM VSTILNGMLD MSFRDRAVQK HQGLKLATAI LQNWRKCDSW WAPDSAPESK 300
  301 TTVLSLLAKM LQIDSTLSFD TNHSSFSEIF TTYANLLADT KLGLHLKGQA VILLPFFTRV 360
  361 TEDRLGDLKH ILEKFIVLNF PMKSDEFPPD SLKYNNYVDC MKKFLDALEL SQSPMLLQLM 420
  421 TDILCREQQH IMEELFQTTF KRIARRSPCV TQLNLLESVY TMFRKGGLLS DVTQAFVDRS 480
  481 LLTLLWHCDL DTLKEFFSRI VVEAIDVLKS RFTKLNDTFD TQITKKMCYY KMLAVMYSRL 540
  541 LKDDVHSKES KINQAFQGSC VAEGNELTKT LLKLCHDAFT ENMAGESQLL EKRRLYHCAA 600
  601 YNCAISLISR VFNELKFYQG FLFSEKPEKN LFIFENLIDL KRCYTFPIEV EVPMERKKKY 660
  661 VEIRKEARDA ANGASGNPRY MSSLSYLTES SLSEEMSQFD FSTGVQSYSY SSQDRKPTTG 720
  721 HFQRREHQDS MAQDDIIELE MDELNQHECM APMTSLIKHM QRNVIAPKGQ EGSISKDLPP 780
  781 WMKFLHDKLE NASVSLNIRL FLAKLVINTE EVFRPYAKHW LGPLLQLAVC ENIGEGIHYM 840
  841 IVEIVATILS WTGLATPTGV PKYEVLANRL LYFLMKYVFH PKRAVFRHNL EIIKTLVECW 900
  901 KECLSIPYRL IFEKFSNKDP NSKDNSVGIQ LLGIVVANNL PPYDLKGDIT SAMYFEALVN 960
  961 NMSFVKYKEV YAAAAEVLGL ILQHVTERKH VIAESVYELV VKQLKQHQNT MEDKFIVCLN1020
 1021 KIVKGFPPLA DRFLNALFFL LPKFHGVMKT LCLEVVLCRA EAITGLYLQL KSKDFLQVMR1080
 1081 HRDDERQKVC LDIIYKMVAK LKPTELRELL NPVVEFVSHP SPTCREQMYN ILMWIHDNYR1140
 1141 DPESQMDEDS QEIFKLAKDV LIQGLIDENL GLQLIIRNFW SHETRLPSNT LDRLLALNSL1200
 1201 YSPKIEVHFL SLATNFLLEM TRMSPDYLNP IFEHPLSECE FQEYTIDPDW RFRSTVLTPM1260
 1261 FIETQAFPST LNTQTQEGSP SDRRQKPGQV RATQQQYDFT PTQTSVERSS FDWLTGSSID1320
 1321 LMADHTVFSS ESLSSSLLFS HKKSEKSQRV SWKSVGPDFG TKKLGLPGDE VDNQVKSGTH1380
 1381 SQTEILRLRR RFLKDQEKLS LLYAKRGLME QKLEKDIKSE LKMKQDAQVV LYRSYRHGDL1440
 1441 PDIQIQHSSL ITPLQAVAQK DPIIAKQLFS SLFSGILKEM HKFRTTSEKN IIIQNLLQDF1500
 1501 NRFLNTTFLF FPPFVSCIQE ISCQHVDLLT LDPAAVRVGC LASLQQPGGI RLLEEALLHL1560
 1561 LPKEPPTKRI RGKTCLPPDV LRWMELAKLY RSIGEYDVLH GIFSSELGTK QDTQNALLAE1620
 1621 ARSDYFQAAN LYKEALNKLE WLDGEPTEAE KEFWEMASLD CYNNLSQWKE LEYRSTVNIG1680
 1681 SENSLDLSKM WSKPFYQETY LPYVIRSKLK LLLQGEDNQS LLTFVDEAMH KELQQMVLEL1740
 1741 QYSQELSLLY ILQDDIDRAT YYIKNAIQIF MQNYSSIDVL LYRSRLAKLQ SVQTLAEIEE1800
 1801 FLNFIRKHGD LSSLGPLRRL LKTWTSRYPD TVTDPMHIWD DIITNRCFFL SKIEERLTVS1860
 1861 PGDHSMSVDE DEDSFAREGS EPKEDAHHIL QSCRFTMKMK MIESSWKQNN FSLSMKLLKE1920
 1921 MHKESKIRES WRMQWIHSFC QLNHCRSHTQ SPQEQVLTML KTITLLDESD ISNYLNKNIQ1980
 1981 AFCDQNILLG TSCRIMADAL SREPACLSGL EKSKTESIFA LSGSNTENTE RVISGLYQRA2040
 2041 FHHLSMAVQS AEEETQLSCW GHEAAAERAH AYMTLVGFCD QQLRKNWKDI QHLWWRKC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle