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Protein Overview: PSA4_MOUSE

General Information:
Name(s) found: PSA4_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|9910830|sp|Q9R1P0.1|PSA4_MOUSE RecName: Full=Proteasome subunit alpha type-4; AltName: Full=Proteasome component C9; AltName: Full=Macropain subunit C9; AltName: Full=Multicatalytic endopeptidase complex subunit C9; AltName: Full=Proteasome subunit L [NCBI NR]
  • gi|74207746|dbj|BAE40115.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|6755196|ref|NP_036096.1| proteasome alpha 4 subunit [Mus musculus] [NCBI NR]
  • gi|5757663|gb|AAD50538.1|AF060093_1 proteasome subunit C9 [Mus musculus] [NCBI NR]
  • gi|26351873|dbj|BAC39573.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|148693889|gb|EDL25836.1| mCG9679 [Mus musculus] [NCBI NR]
  • gi|12805051|gb|AAH01982.1| Proteasome (prosome, macropain) subunit, alpha type 4 [Mus musculus] [NCBI NR]
  • Proteasome subunit alpha type-4 OS=Mus musculus GN=Psma4 PE=1 SV=1 [Swiss-Prot]
  • proteasome (prosome, macropain) subunit, alpha type 4 [HMR_022704-rand.fasta]
  • Proteasome subunit alpha type 4 [ipi.MOUSE.v3.06.fasta]
  • proteasome (prosome, macropain) subunit, alpha type 4 [Mus musculus]gi|12805051|gb|AAH01982.1| Proteasome (prosome, macropain) subunit, alpha type 4 [Mus musculus]gi|5757663|gb|AAD50538.1| proteasome subunit C9 [Mus musculus]gi|26351873|dbj|BAC39573.1| [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Proteasome subunit alpha type 4 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_011966) proteasome (prosome, macropain) subunit, alpha type 4 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • proteasome (prosome, macropain) subunit, alpha type 4 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Proteasome subunit alpha type-4 (Proteasome component C9) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome subunit L) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • mCG9679 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Proteasome (prosome, macropain) subunit, alpha type 4 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • proteasome subunit C9 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Psma4 Proteasome subunit alpha type-4 [mouse-ipi-250309-contam.fasta]
  • proteasome alpha 4 subunit [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta]
  • Proteasome subunit alpha type 4 (Proteasome component C9) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome subunit L) [nr-271106-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Psma4 Proteasome subunit alpha type 4 [zeeyong.fasta]
  • Tax_Id=10090 Gene_Symbol=Psma4 Proteasome subunit alpha type-4 ENSMUSG00000032301 IPI00277001 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • proteasome subunit alpha type-4 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00277001.4|SWISS-PROT:Q9R1P0|TREMBL:Q3TL95;Q3UCF0|ENSEMBL:ENSMUSP00000034848|REFSEQ:NP_036096 Tax_Id=10090 Gene_Symbol=Psma4 Proteasome subunit alpha type-4 [ipi.MOUSE.fasta.20090209]
  • Proteasome subunit alpha type-4 OS=Mus musculus GN=Psma4 [011711_HMR.fasta]
  • sp|Q9R1P0|PSA4_MOUSE Proteasome subunit alpha type-4 OS=Mus musculus GN=Psma4 PE=1 SV=1 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 261 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    cytoplasm [IEA]
    proteasome core complex [IEA]
    proteasome core complex, alpha-subunit complex [IEA]
    proteasome complex [IEA]
    Biological Process: proteolysis involved in cellular protein catabolic process [IEA]
    ubiquitin-dependent protein catabolic process [IEA]
    Molecular Function: endopeptidase activity [IEA]
    threonine-type endopeptidase activity [IEA]
    peptidase activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRYDSRTT IFSPEGRLYQ VEYAMEAIGH AGTCLGILAN DGVLLAAERR NIHKLLDEVF  60
   61 FSEKIYKLNE DMACSVAGIT SDANVLTNEL RLIAQRYLLQ YQEPIPCEQL VTALCDIKQA 120
  121 YTQFGGKRPF GVSLLYIGWD KHYGFQLYQS DPSGNYGGWK ATCIGNNSAA AVSMLKQDYK 180
  181 EGEMTLKSAL ALAVKVLNKT MDVSKLSAEK VEIATLTRES GKTVIRVLKQ KEVEQLIKKH 240
  241 EEEEAKAERE KKEKEQREKD K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..261] PSI-BLAST 70.0 Proteasome alpha subunit (non-catalytic)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • endopeptidase activity
    		•  6.91642761177919 bayes_pls_golite062009
  • peptidase activity
    		•  6.84511694091156 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  6.5973571808298 bayes_pls_golite062009
  • hydrolase activity
    		•  4.47652590304822 bayes_pls_golite062009
  • threonine-type endopeptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • threonine-type peptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • catalytic activity
    		•  1.19663085909195 bayes_pls_golite062009
  • binding
    		•  0.982918122186083 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.448212653390607 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle