YRC Public Data Repository - Protein Structure Prediction

Protein:	PSA4_MOUSE
Organism:	Mus musculus
Length:	261 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSA4_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|91087493 - gi\|91087493\|ref\|XP_968456.1\| PREDICTED: similar to proteasome alpha 4 subunit [Tribolium castaneum]	266.0	[0..1]	[253..1]
gi\|47230708 - gi\|47230708\|emb\|CAF99901.1\| unnamed protein product [Tetraodon nigroviridis]	266.0	[0..2]	[240..1]
gi\|89266778, gi\|... - gi\|89266778\|emb\|CAJ83532.1\| proteasome (prosome macropain) subunit alpha type 4 [Xenopus tropicalis]...	265.0	[0..1]	[238..1]
gi\|76779672, gi\|... - gi\|76779672\|gb\|AAI06639.1\| MGC132180 protein [Xenopus laevis], gi\|148227030\|ref\|NP_001089811.1\| hypo...	263.0	[0..1]	[238..1]
gi\|111058979 - gi\|111058979\|gb\|EAT80099.1\| hypothetical protein SNOG_12286 [Phaeosphaeria nodorum SN15]	263.0	[0..1]	[252..1]
gi\|50752781 - gi\|50752781\|ref\|XP_413742.1\| PREDICTED: similar to Proteasome subunit alpha type 4 (Proteasome compo...	263.0	[0..1]	[240..1]
gi\|109082064 - gi\|109082064\|ref\|XP_001108132.1\| PREDICTED: similar to Proteasome subunit alpha type 4 (Proteasome c...	263.0	[0..2]	[237..48]
gi\|73974928 - gi\|73974928\|ref\|XP_532362.2\| PREDICTED: similar to Proteasome subunit alpha type 4 (Proteasome compo...	262.0	[0..1]	[240..1]
PSA4_PETHY - Proteasome subunit alpha type-4 OS=Petunia hybrida GN=PAC1 PE=2 SV=1	262.0	[0..1]	[249..1]
PSA4_MACFA - Proteasome subunit alpha type-4 OS=Macaca fascicularis GN=PSMA4 PE=2 SV=1	262.0	[0..1]	[237..1]

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Predicted Domain #1

Region A:
Residues: [1-261]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRYDSRTT IFSPEGRLYQ VEYAMEAIGH AGTCLGILAN DGVLLAAERR NIHKLLDEVF  60
   61 FSEKIYKLNE DMACSVAGIT SDANVLTNEL RLIAQRYLLQ YQEPIPCEQL VTALCDIKQA 120
  121 YTQFGGKRPF GVSLLYIGWD KHYGFQLYQS DPSGNYGGWK ATCIGNNSAA AVSMLKQDYK 180
  181 EGEMTLKSAL ALAVKVLNKT MDVSKLSAEK VEIATLTRES GKTVIRVLKQ KEVEQLIKKH 240
  241 EEEEAKAERE KKEKEQREKD K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.0
Match:	1iruC
Description:	Proteasome alpha subunit (non-catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
endopeptidase activity	6.91642761177919	bayes_pls_golite062009
peptidase activity	6.84511694091156	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	6.5973571808298	bayes_pls_golite062009
hydrolase activity	4.47652590304822	bayes_pls_golite062009
threonine-type endopeptidase activity	2.98214579292788	bayes_pls_golite062009
threonine-type peptidase activity	2.98214579292788	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
binding	0.982918122186083	bayes_pls_golite062009
nucleic acid binding	0.448212653390607	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: