YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: FAK1_RAT

General Information:
Name(s) found: FAK1_RAT [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
SHOW ALL
  • Focal adhesion kinase 1 OS=Rattus norvegicus GN=Ptk2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 1055 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoskeleton [IEA]
    nuclear body [IDA]
    focal adhesion [UNKNOWN][IDA][IEA][TAS]
    cytoplasm [UNKNOWN]
    sarcolemma [IDA]
    cytosol [UNKNOWN]
    intercalated disc [IDA]
    nucleolus [IDA]
    basolateral plasma membrane [IDA]
    apical plasma membrane [UNKNOWN][IDA]
    lamellipodium [UNKNOWN]
    Biological Process: signal complex assembly [IEA]
    central nervous system neuron axonogenesis [UNKNOWN]
    positive regulation of vasodilation [IMP]
    protein amino acid autophosphorylation [UNKNOWN]
    JNK cascade [IMP]
    vasculogenesis [UNKNOWN]
    endothelial cell migration [UNKNOWN]
    fat cell differentiation [IEP]
    positive regulation of cell adhesion [IMP]
    protein amino acid phosphorylation [IEA]
    response to mechanical stimulus [IEP]
    positive regulation of smooth muscle cell proliferation [IMP]
    MAPKKK cascade [IMP]
    neuron migration [UNKNOWN]
    response to glucose stimulus [IEP]
    positive regulation of cell growth [IMP]
    negative regulation of axonogenesis [UNKNOWN]
    blood vessel development [UNKNOWN]
    angiogenesis [UNKNOWN]
    response to arsenic [IEP]
    positive regulation of smooth muscle cell migration [IMP]
    cellular chloride ion homeostasis [IMP]
    negative regulation of synaptogenesis [UNKNOWN]
    response to organic substance [IEP]
    establishment of nucleus localization [UNKNOWN]
    positive regulation of synaptic transmission [IMP]
    positive regulation of glial cell proliferation [IMP]
    microtubule cytoskeleton organization [UNKNOWN]
    response to organic cyclic substance [IEP]
    negative regulation of organ growth [UNKNOWN]
    response to drug [IEP]
    negative regulation of apoptosis [IMP]
    extracellular matrix organization [UNKNOWN]
    response to estradiol stimulus [IEP]
    positive regulation of phagocytosis [IMP]
    response to organic nitrogen [IEP]
    negative regulation of cell migration [IMP]
    positive regulation of cell migration [IMP]
    Molecular Function: ATP binding [IEA]
    protein tyrosine kinase activity [IEA][TAS]
    protein binding [UNKNOWN][IDA][IEA]
    protein kinase activity [IEA]
    protein complex binding [IPI]
    SH2 domain binding [UNKNOWN]
    signal transducer activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAYLDPNL NHTPSSSTKT HLGTGTERSP GAMERVLKVF HYFESSNEPT TWASIIRHGD  60
   61 ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW 120
  121 KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMLEIA DQVDQDIALK LGCLEIRRSY 180
  181 WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI 240
  241 LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFNQVQ 300
  301 TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGATQSFII 360
  361 RPQKEGERAL PSIPKLANNE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE 420
  421 RIELGRCIGE GQFGDVHQGV YLSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH 480
  481 PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK 540
  541 RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT 600
  601 SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA 660
  661 YDPSRRPRFT ELKAQLSTIL EEEKVQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY 720
  721 PSPRSSEGFY PSPQHMVQTN HYQISGYPGS HGIPAMAGSI YPGQASLLDQ TELWNHRPQE 780
  781 MSMWQPSVED SAALDLRGMG QVLPPHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS 840
  841 RGSIDREDGS FQGPTGNQHI YQPVGKPDPA APPKKPPRPG APGHLSNLSS ISSPAESYNE 900
  901 GVKPWRLQPQ EISPPPTANL DRSNDKVYEN VTGLVKAVIE MSSKIQPAPP EEYVPMVKEV 960
  961 GLALRTLLAT VDETIPILPA STHREIEMAQ KLLNSDLGEL ISKMKLAQQY VMTSLQQEYK1020
 1021 KQMLTAAHAL AVDAKNLLDV IDQARLKMLG QTRPH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle