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Protein Overview: PSP2

General Information:
Name(s) found: PSP2 / YML017W [SGD]
Description(s) found:
Found 16 descriptions.
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  • Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splicing defects of a mutation in MRS2 and of a conditional mutation in POL1 (DNA polymerase alpha); possible role in mitochondrial mRNA splicing [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 593 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTNNTSNNN GTTKKMSLEE FLGNDTLGES VWDEEDINLD AISNTTNIDI LKQTKAGEHQ  60
   61 RDGHQQHPHG GHGPMNRSRF SNAGPFGGGS MGDFANHHHP LQHQQGPPYI VKFSDLPPRF 120
  121 SNFDIEDLFQ AKFTKFIKFK LFWEINKNPS ISTLKSGSIF DQNFKRDSKV AFVELYTSRD 180
  181 MDKILNYWTT PLKEIYHITT APAEFEDFKD YSTKVKLLTD PKDDAGKPFI TKTQRSKSNP 240
  241 FGSAKPVDTQ SKILDIEEKM ENLHVEDTTT LRASLIPSSD SMATTATGSK ITILKKQTPT 300
  301 EEESHSATPT PKPLSYSEVV ERSVVNETSK KGTPLSKLDS PALELQSKPD KSDEFKGGDE 360
  361 QGFEKGGDDK AQLDVSNDKD KGSETDVDKQ FTFKNVEREH SMSRTKYNGN HNNNNGNFRG 420
  421 SNRYRGGPNG SSYKGGHNNR GNRGGYRGGS SYNNNNNNTN DNNNNNNNSS SNNNNGSRYH 480
  481 DRQNNEEGLT SDSSLDASGN KKNDFTNSTS NTQQYSIFKP ASGFLGQGNN DSIRNNGRGN 540
  541 YNSSGMNGGS RGRGFGRGRG FGRGAYNNRG SRGGRGSSGN YSNYNNRTTD MPL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CAF20 CDC33 EAP1 PSP2 SLF1 TIF1, TIF2 TIF4631 TIF4632 YOR287C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PSP2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] deduced N/A No confident structure predictions are available.
    2 View Details [86..212] MSA 1.007956 View MSA. No confident structure predictions are available.
    3 View Details [213..304] deduced N/A No confident structure predictions are available.
    4 View Details [305..593] MSA 4.058997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle