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Protein Overview: CYP63_ARATH

General Information:
Name(s) found: CYP63_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|7573323|emb|CAB87793.1| cyclophylin-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|24030286|gb|AAN41315.1| putative cyclophylin protein [Arabidopsis thaliana] [NCBI NR]
  • gi|15229425|ref|NP_191899.1| peptidyl-prolyl cis-trans isomerase cyclophilin-type family protein [Arabidopsis thaliana] [NCBI NR]
  • pir||T49181 cyclophylin-like protein - Arabidopsis thaliana [NCBI NR]
  • Peptidyl-prolyl cis-trans isomerase CYP63 OS=Arabidopsis thaliana GN=CYP63 PE=1 SV=1 [Swiss-Prot]
  • (Q9LY75) Cyclophylin-like protein (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) [athaliana3702.FASTAC.txt]
  • putative cyclophylin protein [Arabidopsis thaliana]gi|7573323|emb|CAB87793.1| cyclophylin-like protein [Arabidopsis thaliana]gi|11357239|pir||T49181 cyclophylin-like protein - Arabidopsis thalianagi|15229425|ref|NP_191899.1| peptidyl-prolyl cis-trans i [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Peptidyl-prolyl cis-trans isomerase cyclophilin-type family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: | peptidyl-prolyl cis-trans isomerase cyclophilin-type family protein | chr3:23423424-23426410 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • cyclophylin-like protein [Arabidopsis thaliana] [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • putative cyclophylin protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ATP binding / peptidyl-prolyl cis-trans isomerase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • peptidyl-prolyl cis-trans isomerase cyclophilin-type family protein [Arabidopsis thaliana] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • | Symbols: | Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein | chr3:23412449-23415435 FORWARD LENGTH=570 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein OS=Arabidopsis thaliana GN=MAA21_30 PE=1 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 570 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: RNA splicing [NAS]
    protein folding [ISS]
    Molecular Function: peptidyl-prolyl cis-trans isomerase activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKKKNPNVF LDVSIGGDPV QRIVIELFAD VVPKTAENFR ALCTGEAGVG KSTGKPLHFK  60
   61 GSSFHRVIKG FMAQGGDFSN GNGTGGESIY GGKFSDENFR LDHDGAGVLS MANCGPNTNG 120
  121 SQFFILFKRQ PHLDGKHVVF GKVVEGMAVI KKMELVGTSD GKPTSPVKII DCGETSQIRA 180
  181 HDAAEREKGK SKKSNKNFSP GDVSDREAKE TRKKESNEKR IKRKRRYSSS DSYSSSSDSD 240
  241 SDSESEAYSS SSYESSSSSD GKHRKRKSTT RHKGRRGERK SKGRSGKKKA RPDRKPSTNS 300
  301 SSDTESSSSS DDEKVGHKAI KSVKVDNADQ HANLDDSVKS RSRSPIRRRN QNSRSKSPSR 360
  361 SPVRVLGNGN RSPSRSPVRD LGNGSRSPRE KPTEETVGKS FRSPSPSGVP KRIRKGRGFT 420
  421 ERYSFARKYH TPSPERSPPR HWPDRRNFQD RNRDRYPSNR SYSERSPRGR FRSPPRRRSP 480
  481 PRYNRRRRST SRSPDGYRRR LRDGSRSQSP RHRSRSQSPR KRQPISQDLK SRLGPQRSPI 540
  541 RGGRTSPAES LSPSHSPSPP GKRGLVSYAD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..357] PSI-BLAST 84.39794 Cyclophilin 40; Cyclophilin 40 isomerase domain
    2 View Details [358..570] FFAS03 0.955 No description for 2j63A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein deacetylase activity
    		•  4.3775483906311 bayes_pls_golite062009
  • histone deacetylase activity
    		•  4.29026678196473 bayes_pls_golite062009
  • peptidyl-prolyl cis-trans isomerase activity
    		•  3.73853378771688 bayes_pls_golite062009
  • cis-trans isomerase activity
    		•  3.66963215732405 bayes_pls_golite062009
  • deacetylase activity
    		•  3.49940864924766 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  3.01511519120932 bayes_pls_golite062009
  • RNA binding
    		•  2.94609837984526 bayes_pls_golite062009
  • signal sequence binding
    		•  2.68460419248567 bayes_pls_golite062009
  • isomerase activity
    		•  1.96529188741504 bayes_pls_golite062009
  • binding
    		•  1.46018233647024 bayes_pls_golite062009
  • mRNA binding
    		•  1.45537055700871 bayes_pls_golite062009
  • unfolded protein binding
    		•  1.38124355054041 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.26149030245805 bayes_pls_golite062009
  • peroxisome targeting sequence binding
    		•  1.01220052237687 bayes_pls_golite062009
  • DNA binding
    		•  0.9531600253493 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.939772862764466 bayes_pls_golite062009
  • catalytic activity
    		•  0.748655649755714 bayes_pls_golite062009
  • hydrolase activity
    		•  0.493806105600863 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.408539130322443 bayes_pls_golite062009
  • transcription factor activity
    		•  0.374364600772076 bayes_pls_golite062009
  • drug binding
    		•  0.36339132904137 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.322244688184474 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.286133802341887 bayes_pls_golite062009
  • histone binding
    		•  0.268719695649015 bayes_pls_golite062009
  • protein binding
    		•  0.130251391659493 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  0.105969834846946 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle