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Protein Overview: PNP2_ARATH

General Information:
Name(s) found: PNP2_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Polyribonucleotide nucleotidyltransferase 2, mitochondrial OS=Arabidopsis thaliana GN=PNP2 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 991 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: RNA processing [IEA]
    mRNA catabolic process [IEA]
    Molecular Function: nucleic acid binding [ISS]
    3'-5'-exoribonuclease activity [IEA][ISS]
    RNA binding [IEA][ISS]
    polyribonucleotide nucleotidyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSIVNRASS ASLPNFLAWR ALGFRTICSG RLGFAPSVPD SPVSAGTKIL ESFKEEFEVG  60
   61 SRVVSFETGK IARFANGSVV LGMDETKVLS TVTCAKTDSP RDFLPLTVDY QEKQYAQGLI 120
  121 PNTYMRREGA PKERELLCGR LIDRPIRPLF PTGFYHEVQI MASVLSSDGK QDPDILAANA 180
  181 SSAALMLSDV PWGGPIGVIR IGRICGQFVV NPTMDELSSS DLNLIYACTR DKTMMIDVQS 240
  241 REISEKDLAA ALRLAHPEAV KYLDPQIRLA EKAGKQKKEY KLSMLSDKTL EKVADLAATR 300
  301 IESVFTDPSY GKFERGEALD NIGKDVRKVF EEEGDQESLS ILPKAVDTVR KKVVRSRMIS 360
  361 DGFRVDGRHV DEVRPIYCES HYLPALHGSA LFSRGDTQVL CTVTLGAPAE AQSLDSLVGP 420
  421 PKKRFMLHYS FPPYCTNEVG KRGGLNRREV GHGTLAEKAL LAVLPPEEAF PYTIRINSEV 480
  481 MSSDGSTSMA SVCGGSMALM DAGIPLRAHV AGVSVGLITD VDPSSGEIKD YRIVTDILGL 540
  541 EDHLGDMDFK IAGTRDGVTA IQLDIKPAGI PLDIVCESLE NAREARLQIL DHMERNINSP 600
  601 RGQDGAYSPR LATLKYSNDS LRTLIGPMGV LKRKIEVETG ARLSIDNGTL TIVAKNQDVM 660
  661 EKAQEQVDFI IGRELVVGGV YKGTVSSIKE YGAFVEFPGG QQGLLHMSEL SHEPVSKVSD 720
  721 VLDIGQCITT MCIETDVRGN IKLSRKALLP KPKRKPASDA GKDPVMKESS TVYIENSSVG 780
  781 EIVASMPSIV TPLQKSRLSV PAVVIRTAVE CNEAEKSSPV NDNDKPRRAA TSKPDRKPKS 840
  841 TASKLIATQK EEEALESIAP EETSAECGEI LKQDGKLKSV SPKNNSTASN LVSFSKAKKS 900
  901 TMKENLSENK AEESASVSTR KLKIGTEMTA TVDHVRALGL VLDLGGEIRG MYIFQGDKDK 960
  961 FKKGDTLRVK CTSFNTKGVP VMALVDEEGE E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..748] PSI-BLAST 154.0 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
    2 View Details [749..922] PSI-BLAST 16.0 Catalytic domain of E. coli RNase E
    3 View Details [923..991] PSI-BLAST 3.69897 Solution structure of the S1 RNA binding domain from human hypothetical protein BAA11502

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  3.62650207668685 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.64513435028798 bayes_pls_golite062009
  • exoribonuclease activity
    		•  2.49584565422948 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  2.46667410843173 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  2.04350689362549 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  2.04350689362549 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  2.04218282227834 bayes_pls_golite062009
  • RNA binding
    		•  1.96263727771326 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  1.40738369517171 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.39921751192978 bayes_pls_golite062009
  • structural molecule activity
    		•  1.14103195122487 bayes_pls_golite062009
  • ligase activity
    		•  1.06979791212194 bayes_pls_golite062009
  • transcription termination factor activity
    		•  1.01993495617192 bayes_pls_golite062009
  • binding
    		•  0.953779727473657 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868294430479847 bayes_pls_golite062009
  • ATP-dependent peptidase activity
    		•  0.66778558090199 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.51810239718467 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.504302440847948 bayes_pls_golite062009
  • DNA binding
    		•  0.42372608430605 bayes_pls_golite062009
    		• 0.416217645025381 bayes_pls_golite062009
  • hydrolase activity
    		•  0.355379071501158 bayes_pls_golite062009
  • catalytic activity
    		•  0.10089766806364 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0287026367466632 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • ribonuclease activity
    		•  3.50336342658233 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.61119285841387 bayes_pls_golite062009
  • DNA binding
    		•  2.12131488750007 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  2.04350689362549 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  2.04350689362549 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  2.04218282227834 bayes_pls_golite062009
  • RNA binding
    		•  1.90051536476766 bayes_pls_golite062009
  • binding
    		•  1.81248034004657 bayes_pls_golite062009
  • exoribonuclease activity
    		•  1.69948951519417 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.66992550564008 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.28570711234646 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.10289736160471 bayes_pls_golite062009
  • ligase activity
    		•  1.06979791212194 bayes_pls_golite062009
  • structural molecule activity
    		•  1.00355706247361 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.96886436248958 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.504302440847948 bayes_pls_golite062009
    		• 0.416217645025381 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.398606646713208 bayes_pls_golite062009
  • hydrolase activity
    		•  0.357828165699872 bayes_pls_golite062009
  • translation regulator activity
    		•  0.22908707234671 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.223941674251642 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.179682348023561 bayes_pls_golite062009
  • nuclease activity
    		•  0.138830469179211 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.0717589400404304 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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