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View Structure Prediction Details

Protein: PNP2_ARATH
Organism: Arabidopsis thaliana
Length: 991 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNP2_ARATH.

Description E-value Query
Range
Subject
Range
gi|22124608, gi|... - gi|22124608|ref|NP_668031.1| polynucleotide phosphorylase/polyadenylase [Yersinia pestis KIM], gi|21...
gi|167399496, gi... - gi|167399496|ref|ZP_02305020.1| polyribonucleotide nucleotidyltransferase [Yersinia pestis biovar An...
gi|45435304, gi|... - gi|45440447|ref|NP_991986.1| polynucleotide phosphorylase/polyadenylase [Yersinia pestis biovar Micr...
698.0 [0..21] [748..2]

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Predicted Domain #1
Region A:
Residues: [1-748]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSIVNRASS ASLPNFLAWR ALGFRTICSG RLGFAPSVPD SPVSAGTKIL ESFKEEFEVG  60
   61 SRVVSFETGK IARFANGSVV LGMDETKVLS TVTCAKTDSP RDFLPLTVDY QEKQYAQGLI 120
  121 PNTYMRREGA PKERELLCGR LIDRPIRPLF PTGFYHEVQI MASVLSSDGK QDPDILAANA 180
  181 SSAALMLSDV PWGGPIGVIR IGRICGQFVV NPTMDELSSS DLNLIYACTR DKTMMIDVQS 240
  241 REISEKDLAA ALRLAHPEAV KYLDPQIRLA EKAGKQKKEY KLSMLSDKTL EKVADLAATR 300
  301 IESVFTDPSY GKFERGEALD NIGKDVRKVF EEEGDQESLS ILPKAVDTVR KKVVRSRMIS 360
  361 DGFRVDGRHV DEVRPIYCES HYLPALHGSA LFSRGDTQVL CTVTLGAPAE AQSLDSLVGP 420
  421 PKKRFMLHYS FPPYCTNEVG KRGGLNRREV GHGTLAEKAL LAVLPPEEAF PYTIRINSEV 480
  481 MSSDGSTSMA SVCGGSMALM DAGIPLRAHV AGVSVGLITD VDPSSGEIKD YRIVTDILGL 540
  541 EDHLGDMDFK IAGTRDGVTA IQLDIKPAGI PLDIVCESLE NAREARLQIL DHMERNINSP 600
  601 RGQDGAYSPR LATLKYSNDS LRTLIGPMGV LKRKIEVETG ARLSIDNGTL TIVAKNQDVM 660
  661 EKAQEQVDFI IGRELVVGGV YKGTVSSIKE YGAFVEFPGG QQGLLHMSEL SHEPVSKVSD 720
  721 VLDIGQCITT MCIETDVRGN IKLSRKAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 154.0
Match: 1e3hA
Description: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 3.62650207668685 bayes_pls_golite062009
transcription regulator activity 2.64513435028798 bayes_pls_golite062009
exoribonuclease activity 2.49584565422948 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 2.46667410843173 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 2.04350689362549 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 2.04350689362549 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 2.04218282227834 bayes_pls_golite062009
RNA binding 1.96263727771326 bayes_pls_golite062009
3'-5'-exoribonuclease activity 1.40738369517171 bayes_pls_golite062009
structural constituent of ribosome 1.39921751192978 bayes_pls_golite062009
structural molecule activity 1.14103195122487 bayes_pls_golite062009
ligase activity 1.06979791212194 bayes_pls_golite062009
transcription termination factor activity 1.01993495617192 bayes_pls_golite062009
binding 0.953779727473657 bayes_pls_golite062009
nucleic acid binding 0.868294430479847 bayes_pls_golite062009
ATP-dependent peptidase activity 0.66778558090199 bayes_pls_golite062009
carbohydrate kinase activity 0.51810239718467 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.504302440847948 bayes_pls_golite062009
DNA binding 0.42372608430605 bayes_pls_golite062009
0.416217645025381 bayes_pls_golite062009
hydrolase activity 0.355379071501158 bayes_pls_golite062009
catalytic activity 0.10089766806364 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0287026367466632 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [749-922]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPKPKRKPAS DAGKDPVMKE SSTVYIENSS VGEIVASMPS IVTPLQKSRL SVPAVVIRTA  60
   61 VECNEAEKSS PVNDNDKPRR AATSKPDRKP KSTASKLIAT QKEEEALESI APEETSAECG 120
  121 EILKQDGKLK SVSPKNNSTA SNLVSFSKAK KSTMKENLSE NKAEESASVS TRKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.0
Match: 2bx2L
Description: Catalytic domain of E. coli RNase E
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [923-991]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIGTEMTATV DHVRALGLVL DLGGEIRGMY IFQGDKDKFK KGDTLRVKCT SFNTKGVPVM  60
   61 ALVDEEGEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1wi5A
Description: Solution structure of the S1 RNA binding domain from human hypothetical protein BAA11502
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 3.50336342658233 bayes_pls_golite062009
nucleic acid binding 2.61119285841387 bayes_pls_golite062009
DNA binding 2.12131488750007 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 2.04350689362549 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 2.04350689362549 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 2.04218282227834 bayes_pls_golite062009
RNA binding 1.90051536476766 bayes_pls_golite062009
binding 1.81248034004657 bayes_pls_golite062009
exoribonuclease activity 1.69948951519417 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.66992550564008 bayes_pls_golite062009
structural constituent of ribosome 1.28570711234646 bayes_pls_golite062009
structure-specific DNA binding 1.10289736160471 bayes_pls_golite062009
ligase activity 1.06979791212194 bayes_pls_golite062009
structural molecule activity 1.00355706247361 bayes_pls_golite062009
single-stranded DNA binding 0.96886436248958 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.504302440847948 bayes_pls_golite062009
0.416217645025381 bayes_pls_golite062009
transcription regulator activity 0.398606646713208 bayes_pls_golite062009
hydrolase activity 0.357828165699872 bayes_pls_golite062009
translation regulator activity 0.22908707234671 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.223941674251642 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.179682348023561 bayes_pls_golite062009
nuclease activity 0.138830469179211 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.0717589400404304 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle