Protein Overview: CUL2_ARATH

General Information:
Name(s) found:	CUL2_ARATH [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6056404\|gb\|AAF02868.1\|AC009525_2 Similar to cullin proteins [Arabidopsis thaliana] [NCBI NR] pir\|\|D86160 hypothetical protein F22D16.2 - Arabidopsis thaliana [NCBI NR] gi\|22329305\|ref\|NP_171797.2\| CUL2 (CULLIN 2); ubiquitin protein ligase binding [Arabidopsis thaliana] [NCBI NR] Cullin-2 OS=Arabidopsis thaliana GN=CUL2 PE=1 SV=1 [Swiss-Prot] (Q9SRZ0) F22D16.2 protein [athaliana3702.FASTAC.txt] Similar to cullin proteins [Arabidopsis thaliana]gi\|25354603\|pir\|\|D86160 hypothetical protein F22D16.2 - Arabidopsis thalianagi\|22329305\|ref\|NP_171797.2\| cullin family protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas] Tax_Id=3702 Cullin family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta] \| Symbols: ATCUL2, CUL2 \| CUL2 (cullin 2); ubiquitin protein ligase binding \| chr1:677869-681212 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta] Similar to cullin proteins [Arabidopsis thaliana] [nr-271106-contam.fasta] CUL2 [Arabidopsis thaliana] [nr-271106-contam.fasta] \| Symbols: CUL2, ATCUL2 \| cullin 2 \| chr1:677869-681212 FORWARD LENGTH=742 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
Organism:	Arabidopsis thaliana
Length:	742 amino acids
Gene Ontology:
Cellular Component:	chloroplast envelope [IDA] SCF ubiquitin ligase complex [ISS]
Biological Process:	cell cycle [ISS] ubiquitin-dependent protein catabolic process [IEA]
Molecular Function:	ubiquitin protein ligase binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKDSVLEA GWSVMEAGVA KLQKILEEVP DEPPFDPVQR MQLYTTVHNL CTQKPPNDYS  60
   61 QQIYDRYGGV YVDYNKQTVL PAIREKHGEY MLRELVKRWA NQKILVRWLS HFFEYLDRFY 120
  121 TRRGSHPTLS AVGFISFRDL VYQELQSKAK DAVLALIHKE REGEQIDRAL LKNVIDVYCG 180
  181 NGMGELVKYE EDFESFLLED SASYYSRNAS RWNQENSCPD YMIKAEESLR LEKERVTNYL 240
  241 HSTTEPKLVA KVQNELLVVV AKQLIENEHS GCRALLRDDK MDDLARMYRL YHPIPQGLDP 300
  301 VADLFKQHIT VEGSALIKQA TEAATDKAAS TSGLKVQDQV LIRQLIDLHD KFMVYVDECF 360
  361 QKHSLFHKAL KEAFEVFCNK TVAGVSSAEI LATYCDNILK TGGGIEKLEN EDLELTLEKV 420
  421 VKLLVYISDK DLFAEFFRKK QARRLLFDRN GNDYHERSLL TKFKELLGAQ FTSKMEGMLT 480
  481 DMTLAKEHQT NFVEFLSVNK TKKLGMDFTV TVLTTGFWPS YKTTDLNLPI EMVNCVEAFK 540
  541 AYYGTKTNSR RLSWIYSLGT CQLAGKFDKK TIEIVVTTYQ AAVLLLFNNT ERLSYTEILE 600
  601 QLNLGHEDLA RLLHSLSCLK YKILIKEPMS RNISNTDTFE FNSKFTDKMR RIRVPLPPMD 660
  661 ERKKIVEDVD KDRRYAIDAA LVRIMKSRKV LGHQQLVSEC VEHLSKMFKP DIKMIKKRIE 720
  721 DLISRDYLER DTDNPNTFKY LA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
ubiquitin-protein ligase activity	9.47178230940453	bayes_pls_golite062009
small conjugating protein ligase activity	9.15192834197166	bayes_pls_golite062009
acid-amino acid ligase activity	8.12051073361876	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	6.87003086224111	bayes_pls_golite062009
transcription regulator activity	4.76121492612224	bayes_pls_golite062009
transcription factor activity	3.7855017556511	bayes_pls_golite062009
ligase activity	3.66453881539688	bayes_pls_golite062009
transcription repressor activity	2.39237599101586	bayes_pls_golite062009
binding	2.3219000606044	bayes_pls_golite062009
protein binding	2.20237620151495	bayes_pls_golite062009
vasopressin activated calcium mobilizing receptor activity	2.15618962838168	bayes_pls_golite062009
transcription activator activity	2.05043065144612	bayes_pls_golite062009
nucleic acid binding	1.54797684894025	bayes_pls_golite062009
DNA binding	1.42215436462553	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.23862224095769	bayes_pls_golite062009
transporter activity	0.891050405674973	bayes_pls_golite062009
transmembrane transporter activity	0.648150681919233	bayes_pls_golite062009
transcription factor binding	0.612315945412079	bayes_pls_golite062009
substrate-specific transporter activity	0.368917395770011	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.249771970501337	bayes_pls_golite062009
catalytic activity	0.201606344181603	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.146182977030285	bayes_pls_golite062009
hydrolase activity	0.140191206949582	bayes_pls_golite062009
structure-specific DNA binding	0.117670813298683	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.107671044044222	bayes_pls_golite062009
transferase activity	0.064832527337659	bayes_pls_golite062009
specific transcriptional repressor activity	0.0565989703351002	bayes_pls_golite062009
sequence-specific DNA binding	0.0102780098866235	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..742]	PSI-BLAST	1000.0	No description for 2hyeC was found.

Protein Overview: CUL2_ARATH

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: