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Protein Overview: CSN2_ARATH

General Information:
Name(s) found: CSN2_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|55976551|sp|Q8W207.1|CSN2_ARATH RecName: Full=COP9 signalosome complex subunit 2; Short=Signalosome subunit 2; AltName: Full=Protein FUSCA 12 [NCBI NR]
  • gi|21593214|gb|AAM65163.1| putative PCI domain protein [Arabidopsis thaliana] [NCBI NR]
  • gi|20197415|gb|AAC77857.2| COP9 complex subunit CSN2, putative [Arabidopsis thaliana] [NCBI NR]
  • gi|18401293|ref|NP_565632.1| FUS12 (FUSCA 12) [Arabidopsis thaliana] [NCBI NR]
  • gi|18056655|gb|AAL58101.1|AF395058_1 CSN complex subunit 2 [Arabidopsis thaliana] [NCBI NR]
  • COP9 signalosome complex subunit 2 OS=Arabidopsis thaliana GN=CSN2 PE=1 SV=1 [Swiss-Prot]
  • (Q8W207) CSN complex subunit 2 (COP9 complex subunit CSN2, putative) (Putative PCI domain protein) [athaliana3702.FASTAC.txt]
  • putative PCI domain protein [Arabidopsis thaliana]gi|20197415|gb|AAC77857.2| COP9 complex subunit CSN2, putative [Arabidopsis thaliana]gi|18056655|gb|AAL58101.1| CSN complex subunit 2 [Arabidopsis thaliana]gi|18401293|ref|NP_565632.1| COP9 signalosome [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 COP9 signalosome complex subunit 2 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATCSN2, COP12, FUS12 | FUS12 (FUSCA 12) | chr2:11526762-11529490 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • COP9 complex subunit CSN2, putative [Arabidopsis thaliana] [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • putative PCI domain protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • CSN complex subunit 2 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • COP9 signalosome complex subunit 2 (Signalosome subunit 2) (FUSCA protein 12) (FUSCA12) [nr-271106-contam.fasta]
  • FUS12 (FUSCA 12) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: FUS12, ATCSN2, COP12, CSN2 | proteasome family protein | chr2:11519684-11522412 REVERSE LENGTH=439 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 439 amino acids

    Gene Ontology:
    Cellular Component: nucleus [TAS]
    signalosome [IPI][TAS]
    Biological Process: photomorphogenesis [TAS]
    protein catabolic process [TAS]
    cullin deneddylation [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASDADMEDY GFEYSDEEQE EQDVDIENQY YNSKGMVETE PEEALSGFAE VVQMEPEKAD  60
   61 WGFKALKQTV KIYYRLGKYK EMMEAYTEML TYIKSAVTRN YSEKCINNIM DFVSGSASQN 120
  121 TGLLQEFYQT TLKALEEAKN ERLWFKTNLK LCNIWFDIGE YRRMTKILKE LHKSCQKEDG 180
  181 TDDQKKGSQL LEVYAIEIQI YTETKDNKKL KQLYHKALAI KSAIPHPRIM GIIRECGGKM 240
  241 HMAERQWEEA ATDFFEAFKN YDEAGNQRRI QCLKYLVLAN MLMESEVNPF DGQEAKPYKN 300
  301 DPEILAMTNL IAAYQRNEII EFERILKSNR RTIMDDPFIR NYMEDLLKKV RTQVLLKLIK 360
  361 PYTKIGIPFI SKELNVPETD VTELLVSLIL DSRIDGHIDE MNRYLLRGDS GNGRKLHKAV 420
  421 DKWNSQLKSL SSNITSRVC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..350] PSI-BLAST 4.045757 No description for 2gw1A was found.
    2 View Details [351..439] FFAS03 2.94 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.23858959608048 bayes_pls_golite062009
  • DNA binding
    		•  4.78517210147551 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.72059012764202 bayes_pls_golite062009
  • transcription factor activity
    		•  4.02736190679869 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.60278632732466 bayes_pls_golite062009
  • binding
    		•  3.37660003833383 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.41045867230388 bayes_pls_golite062009
  • hydrolase activity
    		•  2.37143167527915 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.21432668306508 bayes_pls_golite062009
  • transcription activator activity
    		•  2.13702350917359 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.28416365596732 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.23579329819576 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.12766532785895 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.761838897494019 bayes_pls_golite062009
  • transcription factor binding
    		•  0.752335897765285 bayes_pls_golite062009
  • protein binding
    		•  0.726445167461826 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.710995647413393 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.49516964123412 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.490809930581315 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.281229260644949 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.252392400929265 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.237208016899812 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.171423850692861 bayes_pls_golite062009
  • transferase activity
    		•  0.10058871838551 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle