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View Structure Prediction Details

Protein: CSN2_ARATH
Organism: Arabidopsis thaliana
Length: 439 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CSN2_ARATH.

Description E-value Query
Range
Subject
Range
gi|62751437, gi|... - gi|62751437|ref|NP_001015820.1| COP9 constitutive photomorphogenic homolog subunit 2 [Xenopus (Silur...
233.0 [0..6] [438..12]

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Predicted Domain #1
Region A:
Residues: [1-350]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASDADMEDY GFEYSDEEQE EQDVDIENQY YNSKGMVETE PEEALSGFAE VVQMEPEKAD  60
   61 WGFKALKQTV KIYYRLGKYK EMMEAYTEML TYIKSAVTRN YSEKCINNIM DFVSGSASQN 120
  121 TGLLQEFYQT TLKALEEAKN ERLWFKTNLK LCNIWFDIGE YRRMTKILKE LHKSCQKEDG 180
  181 TDDQKKGSQL LEVYAIEIQI YTETKDNKKL KQLYHKALAI KSAIPHPRIM GIIRECGGKM 240
  241 HMAERQWEEA ATDFFEAFKN YDEAGNQRRI QCLKYLVLAN MLMESEVNPF DGQEAKPYKN 300
  301 DPEILAMTNL IAAYQRNEII EFERILKSNR RTIMDDPFIR NYMEDLLKKV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.045757
Match: 2gw1A
Description: No description for 2gw1A was found.

Predicted Domain #2
Region A:
Residues: [351-439]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTQVLLKLIK PYTKIGIPFI SKELNVPETD VTELLVSLIL DSRIDGHIDE MNRYLLRGDS  60
   61 GNGRKLHKAV DKWNSQLKSL SSNITSRVC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.94
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.23858959608048 bayes_pls_golite062009
DNA binding 4.78517210147551 bayes_pls_golite062009
nucleic acid binding 4.72059012764202 bayes_pls_golite062009
transcription factor activity 4.02736190679869 bayes_pls_golite062009
transcription repressor activity 3.60278632732466 bayes_pls_golite062009
binding 3.37660003833383 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.41045867230388 bayes_pls_golite062009
hydrolase activity 2.37143167527915 bayes_pls_golite062009
sequence-specific DNA binding 2.21432668306508 bayes_pls_golite062009
transcription activator activity 2.13702350917359 bayes_pls_golite062009
small conjugating protein ligase activity 1.28416365596732 bayes_pls_golite062009
structure-specific DNA binding 1.23579329819576 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.12766532785895 bayes_pls_golite062009
acid-amino acid ligase activity 0.761838897494019 bayes_pls_golite062009
transcription factor binding 0.752335897765285 bayes_pls_golite062009
protein binding 0.726445167461826 bayes_pls_golite062009
specific transcriptional repressor activity 0.710995647413393 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.49516964123412 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.490809930581315 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.281229260644949 bayes_pls_golite062009
transcription corepressor activity 0.252392400929265 bayes_pls_golite062009
double-stranded DNA binding 0.237208016899812 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.171423850692861 bayes_pls_golite062009
transferase activity 0.10058871838551 bayes_pls_golite062009

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