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Protein Overview: LKHA4_ARATH

General Information:
Name(s) found: LKHA4_ARATH [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • Leukotriene A-4 hydrolase homolog OS=Arabidopsis thaliana GN=LKHA4 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 616 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: leukotriene biosynthetic process [IEA]
    proteolysis [IEA][ISS]
    Molecular Function: zinc ion binding [IEA]
    binding [IEA]
    metallopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPIDPHSFT DSSHPLTTHV ALSLYLDFNT SIIHGSALLT LSSAFSGELS LDTRCISIAM  60
   61 VLDPLTLEPI PYSVSTTPDR IRGTEVVVVL SGQSSLLIVY STSPSASALQ WLSPLQTFSK 120
  121 LHPYVYTQCQ AIHARSIFPC QDTPAARIRY DVVMNIPNSL SAVMSARHVR RRLAVPEEAK 180
  181 HLEAGSLGSS LWCGEDRVVE EFAMEQPIPP YLFAFAVGEL GFREVGPRTR VYTESAAIEV 240
  241 LDAAALEFAG TEDMIKQGEK LFGDYEWERF DLLVLPPSFP YGGMENPRMV FLTPTVIKGD 300
  301 ATGAQVVAHE LAHSWTGNLI TNINNEHFWL NEGFTTYAER RIVEVVQGAD IATLNIGIGW 360
  361 RGLTDEMERF KDNLECTKLW NKQEGVDPDD VYSQVPYEKG FQFVLRIERQ IGRTAFDEFL 420
  421 KKYIATFKFK SIDTNTFLEF LKANIPGIEK EINLQLWTEG VGIPEDAYEP VSTIYTKIIS 480
  481 LAKEFKEGKM PSEDDVAEWN GQEWELYLEN LPKSCEPSQV MALDKRYRLA ESKDYEVKVS 540
  541 FLQLAVTSKC REYHGEVKKT LKEVGRMKYL RPLFTALAQS GGTEEKQLAK QVFAEARETY 600
  601 HPIAQGVVES ILSKYI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..616] PSI-BLAST 125.0 Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  3.71606469379318 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  3.36548300377296 bayes_pls_golite062009
  • endopeptidase activity
    		•  2.68178232987479 bayes_pls_golite062009
  • hydrolase activity
    		•  2.4180994157249 bayes_pls_golite062009
  • metallopeptidase activity
    		•  2.1215666797696 bayes_pls_golite062009
  • metalloendopeptidase activity
    		•  1.55964119804062 bayes_pls_golite062009
  • binding
    		•  1.29310089768477 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.00618489031368 bayes_pls_golite062009
  • catalytic activity
    		•  0.891187593353827 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.364756038518376 bayes_pls_golite062009
  • protein binding
    		•  0.278366242068789 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.21808506596674 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0671277591944419 bayes_pls_golite062009
  • DNA binding
    		•  0.0559585284546991 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.74

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle