Protein Overview: SPBC12C2.11

General Information:
Name(s) found:	SPBC12C2.11 [Sanger Pombe]
Description(s) found: Found 17 descriptions. SHOW ALL	glutamine-fructose-6-phosphate transaminase [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	696 amino acids
Gene Ontology:
Cellular Component:	cytosol [IDA]
Biological Process:	chitin biosynthetic process [ISS] external encapsulating structure organization [ISS]
Molecular Function:	sugar binding [IEA] glutamine-fructose-6-phosphate transaminase (isomerizing) activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGIFGYINY LVERDRGYIL KTLVKGLKRL EYRGYDSSGC AVDGDEGEDF IMFKEVGNVS  60
   61 KLEASIKGSN VNKSTKFINH CAISHTRWAT HGIPSPINCH PQRSDPHSEF IVVHNGILTN 120
  121 YRELRTVLES RGMVFESETD TECVAKLAKF IYDTTPGVDF TSLAKLVFRE LEGAYALLIK 180
  181 SSHYPGEVVA TRRGSPLIVG VKSEQKLKVD FVDVEFPEPA EGLPGTPKPT SLHPVFSNPA 240
  241 TNGMLRGDKP DLLHRAQSRA FVSGEGVPGP IEYFFASDAT PIIEYTKRVM FLEDDDIAHV 300
  301 RDGELHVHRL RREGGGSTTR TIETLEMEIA SVMKGNYDHY MIKEICEQPD SLLNTMRGRV 360
  361 NFVNRLVTLG GLESYYDIIR KSRRLIFVAC GTSYHSCVAV RPLFEELTNI PVVVELASDF 420
  421 VDRCPSVFRD DTFIFVSQSG ETADSLLALQ YTLENGALAI GVVNCVGSSI SRKTHCGVHI 480
  481 NAGPEICVAS TKAYTSQYVA LVLMALYLSR DSVSRLERRN EIIDGLAEIG EKVQETLHLN 540
  541 AAIKQTAIEQ LINKDKMLII GRGYHYATAL EGALKVKEIS YTHAEGVLAG ELKHGVLALV 600
  601 DNDMPIVMLL PDDYNFPKAW NAFEQVRARG GKPIIITDKK LDNLEGFTII KVPKTVDCLQ 660
  661 GILNVIPFQL LSYWLAVKRG HNVDQPRNLA KSVTVE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..233]	PSI-BLAST	53.0	Glutaminase domain of glucosamine 6-phosphate synthase complexed with glutamate
2	View Details	[234..347]	FFAS03	1.54	"Isomerase domain" of glucosamine 6-phosphate synthase (GLMS); Glucosamine 6-phosphate synthase, N-terminal domain
3	View Details	[348..645]	PSI-BLAST	10.522879	Crystal structure of native phosphoglucose/phosphomannose isomerase from Pyrobaculum aerophilum
4	View Details	[646..696]	PSI-BLAST	90.0	No description for 2pocA was found.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
peptidase activity	1.34295853726897	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	1.16226272745141	bayes_pls_golite062009
nucleic acid binding	0.798789250029517	bayes_pls_golite062009
endopeptidase activity	0.759765292911898	bayes_pls_golite062009
binding	0.541510243044181	bayes_pls_golite062009
transferase activity	0.526806728662348	bayes_pls_golite062009

2

No functions predicted.

3

Term	Confidence	Notes
glutamine-fructose-6-phosphate transaminase (isomerizing) activity	4.12465195642555	bayes_pls_golite062009
glucose-6-phosphate isomerase activity	2.74527495029339	bayes_pls_golite062009
D-sedoheptulose 7-phosphate isomerase activity	2.03357282678145	bayes_pls_golite062009
intramolecular oxidoreductase activity	1.99606027864666	bayes_pls_golite062009
catalytic activity	1.5278037255884	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	1.49939040101274	bayes_pls_golite062009
sugar binding	1.40175307923331	bayes_pls_golite062009
transferase activity	1.20219571915061	bayes_pls_golite062009
isomerase activity	0.875614547872629	bayes_pls_golite062009
binding	0.8320110584046	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	0.329741341879618	bayes_pls_golite062009
transaminase activity	0.307877519336205	bayes_pls_golite062009
protein binding	0.152745336606766	bayes_pls_golite062009
carbohydrate binding	0.0870260775261698	bayes_pls_golite062009

4

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle