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Protein Overview: pdr-1

General Information:
Name(s) found: pdr-1 / CE31713 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00003967 locus:pdr-1 status:Confirmed UniProt:Q9XUS3 protein_id:CAB04599.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 386 amino acids

    Gene Ontology:
    Cellular Component: ubiquitin ligase complex [IPI]
    cytoplasm [IDA]
    neuronal cell body [IDA]
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    protein modification process [IEALink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDEISILIQ DRKTGQRRNL TLNINITGNI EDLTKDVEKL TEIPSDELEV VFCGKKLSKS  60
   61 TIMRDLSLTP ATQIMLLRPK FNSHNENGAT TAKITTDSSI LGSFYVWCKN CDDVKRGKLR 120
  121 VYCQKCSSTS VLVKSEPQNW SDVLKSKRIP AVCEECCTPG LFAEFKFKCL ACNDPAAALT 180
  181 HVRGNWQMTE CCVCDGKEKV IFDLGCNHIT CQFCFRDYLL SQLERFGFVN QPPHGFTIFC 240
  241 PYPGCNRVVQ DVHHFHIMGQ TSYSEYQRKA TERLIAVDDK GVTCPNVSCG QSFFWEPYDD 300
  301 DGRSQCPDCF FSFCRKCFER NCVCQSEDDL TRTTIDATTR RCPKCHVATE RNGGCAHIHC 360
  361 TSCGMDWCFK CKTEWKEECQ WDHWFN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] PSI-BLAST 16.30103 Structure of the DNA repair protein hHR23a
    2 View Details [128..243] PSI-BLAST 5.0 Solution Structure of the RING finger Domain of the human UbcM4-interacting Protein 4
    3 View Details [244..310] FFAS03 1.3 No description for 2jmoA was found.
    4 View Details [311..386] PSI-BLAST 8.09691 Solution Structure of the C-terminal RING from a RING-IBR-RING (TRIAD) motif

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  3.71144418714309 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  3.30801071565148 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  2.72499875710239 bayes_pls_golite062009
  • binding
    		•  2.35732272412639 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.20811136250556 bayes_pls_golite062009
  • protein tag
    		•  2.15059229834935 bayes_pls_golite062009
  • protein binding
    		•  1.86841453215444 bayes_pls_golite062009
  • tubulin binding
    		•  1.45941587790919 bayes_pls_golite062009
  • microtubule binding
    		•  1.18009100234328 bayes_pls_golite062009
  • signal transducer activity
    		•  0.84497408888751 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.84497408888751 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.753885975469065 bayes_pls_golite062009
  • hydrolase activity
    		•  0.614233748923048 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.599634454232833 bayes_pls_golite062009
  • structural molecule activity
    		•  0.576819726104993 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.460490130771208 bayes_pls_golite062009
  • kinase activity
    		•  0.456485925435821 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.412533160717297 bayes_pls_golite062009
  • protein kinase activity
    		•  0.353433845798143 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.334601927012824 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.319650090047305 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.315664702789604 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.162163146322721 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.135340673572074 bayes_pls_golite062009
    2
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  5.97121728620188 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.78935175140238 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.75377804653841 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.57382484274962 bayes_pls_golite062009
  • binding
    		•  2.35777587677918 bayes_pls_golite062009
  • protein binding
    		•  1.5975811408548 bayes_pls_golite062009
  • ligase activity
    		•  1.28164271879607 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  0.786612602432575 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.549461161056205 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52386813728704 bayes_pls_golite062009
  • transcription factor binding
    		•  0.40077737329629 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.345429067492564 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.159023519781458 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.125491277540945 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.0198730391417716 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  5.97121728620188 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.78935175140238 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.75377804653841 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.57382484274962 bayes_pls_golite062009
  • binding
    		•  2.35777587677918 bayes_pls_golite062009
  • protein binding
    		•  1.5975811408548 bayes_pls_golite062009
  • ligase activity
    		•  1.28164271879607 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  0.786612602432575 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.549461161056205 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52386813728704 bayes_pls_golite062009
  • transcription factor binding
    		•  0.40077737329629 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.345429067492564 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.159023519781458 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.125491277540945 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.0198730391417716 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle