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View Structure Prediction Details

Protein: pdr-1
Organism: Caenorhabditis elegans
Length: 386 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pdr-1.

Description E-value Query
Range
Subject
Range
gi|113205856, gi... - gi|85718640|gb|ABC75246.1| parkin [Sus scrofa], gi|113205856|ref|NP_001038068.1| parkin [Sus scrofa]
216.0 [0..8] [386..1]

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Predicted Domain #1
Region A:
Residues: [1-127]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDEISILIQ DRKTGQRRNL TLNINITGNI EDLTKDVEKL TEIPSDELEV VFCGKKLSKS  60
   61 TIMRDLSLTP ATQIMLLRPK FNSHNENGAT TAKITTDSSI LGSFYVWCKN CDDVKRGKLR 120
  121 VYCQKCS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.30103
Match: 1oqyA
Description: Structure of the DNA repair protein hHR23a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 3.71144418714309 bayes_pls_golite062009
ubiquitin-protein ligase activity 3.30801071565148 bayes_pls_golite062009
acid-amino acid ligase activity 2.72499875710239 bayes_pls_golite062009
binding 2.35732272412639 bayes_pls_golite062009
cytoskeletal protein binding 2.20811136250556 bayes_pls_golite062009
protein tag 2.15059229834935 bayes_pls_golite062009
protein binding 1.86841453215444 bayes_pls_golite062009
tubulin binding 1.45941587790919 bayes_pls_golite062009
microtubule binding 1.18009100234328 bayes_pls_golite062009
signal transducer activity 0.84497408888751 bayes_pls_golite062009
molecular transducer activity 0.84497408888751 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.753885975469065 bayes_pls_golite062009
hydrolase activity 0.614233748923048 bayes_pls_golite062009
structural constituent of ribosome 0.599634454232833 bayes_pls_golite062009
structural molecule activity 0.576819726104993 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.460490130771208 bayes_pls_golite062009
kinase activity 0.456485925435821 bayes_pls_golite062009
SUMO ligase activity 0.412533160717297 bayes_pls_golite062009
protein kinase activity 0.353433845798143 bayes_pls_golite062009
GTPase regulator activity 0.334601927012824 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.319650090047305 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.315664702789604 bayes_pls_golite062009
enzyme regulator activity 0.162163146322721 bayes_pls_golite062009
protein serine/threonine kinase activity 0.135340673572074 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [128-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STSVLVKSEP QNWSDVLKSK RIPAVCEECC TPGLFAEFKF KCLACNDPAA ALTHVRGNWQ  60
   61 MTECCVCDGK EKVIFDLGCN HITCQFCFRD YLLSQLERFG FVNQPPHGFT IFCPYP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1wimA
Description: Solution Structure of the RING finger Domain of the human UbcM4-interacting Protein 4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.97121728620188 bayes_pls_golite062009
small conjugating protein ligase activity 5.78935175140238 bayes_pls_golite062009
acid-amino acid ligase activity 4.75377804653841 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 2.57382484274962 bayes_pls_golite062009
binding 2.35777587677918 bayes_pls_golite062009
protein binding 1.5975811408548 bayes_pls_golite062009
ligase activity 1.28164271879607 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.786612602432575 bayes_pls_golite062009
ubiquitin-specific protease activity 0.549461161056205 bayes_pls_golite062009
hydrolase activity 0.52386813728704 bayes_pls_golite062009
transcription factor binding 0.40077737329629 bayes_pls_golite062009
transcription regulator activity 0.345429067492564 bayes_pls_golite062009
cysteine-type peptidase activity 0.159023519781458 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
nucleic acid binding 0.125491277540945 bayes_pls_golite062009
transcription repressor activity 0.0198730391417716 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [244-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GCNRVVQDVH HFHIMGQTSY SEYQRKATER LIAVDDKGVT CPNVSCGQSF FWEPYDDDGR  60
   61 SQCPDCF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.3
Match: 2jmoA
Description: No description for 2jmoA was found.

Predicted Domain #4
Region A:
Residues: [311-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSFCRKCFER NCVCQSEDDL TRTTIDATTR RCPKCHVATE RNGGCAHIHC TSCGMDWCFK  60
   61 CKTEWKEECQ WDHWFN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.09691
Match: 1wd2A
Description: Solution Structure of the C-terminal RING from a RING-IBR-RING (TRIAD) motif
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.97121728620188 bayes_pls_golite062009
small conjugating protein ligase activity 5.78935175140238 bayes_pls_golite062009
acid-amino acid ligase activity 4.75377804653841 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 2.57382484274962 bayes_pls_golite062009
binding 2.35777587677918 bayes_pls_golite062009
protein binding 1.5975811408548 bayes_pls_golite062009
ligase activity 1.28164271879607 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.786612602432575 bayes_pls_golite062009
ubiquitin-specific protease activity 0.549461161056205 bayes_pls_golite062009
hydrolase activity 0.52386813728704 bayes_pls_golite062009
transcription factor binding 0.40077737329629 bayes_pls_golite062009
transcription regulator activity 0.345429067492564 bayes_pls_golite062009
cysteine-type peptidase activity 0.159023519781458 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
nucleic acid binding 0.125491277540945 bayes_pls_golite062009
transcription repressor activity 0.0198730391417716 bayes_pls_golite062009

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