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Protein Overview: tbh-1

General Information:
Name(s) found: tbh-1 / CE31553 [WormBase]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • WBGene00006541 locus:tbh-1 Tyramine beta-hydroxylase status:Confirmed UniProt:Q9XTQ6 protein_id:CAB17071.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 585 amino acids

    Gene Ontology:
    Cellular Component: synapse [IDALink to PubMed article]
    Biological Process: histidine catabolic process [IEALink to PubMed article]
    Molecular Function: copper ion binding [IEALink to PubMed article]
    monooxygenase activity [IEALink to PubMed article]
    dopamine beta-monooxygenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSAVALLFL LVAYCGGVVH AGEIVAELYH TNVTVKWHTD YERQLVDFSI WFGASTPDVL  60
   61 FLGFSDFGDT NNSDVLMYYN SKKEIKDAYT NRDFKITSDL QQDFQLLRKR KDHIVVRRKL 120
  121 TTCDSRDYAF LPGTTQFYIA ASWGSTNLVD IRDKRWVVDK KFGKVIEGPT DQPNIEEEPA 180
  181 ALEKDVKVVI VNSNSPDPIP NVETTYKCII RKMPFDTVNN MYHVVRMEPY VTPGNEHLVH 240
  241 HMEIFMCRDE VEEWSGSCND PKKPPKSKSC SHVIAAWAMG EGPIHYPKEA GLPIGGKGKN 300
  301 AYVMVEIHYN NPELHKGVID SSGFQFFVTG QLRKYDAGIM ELGLIYSDAN SVPPNQKAWA 360
  361 MNGYCPSQCT KNLPEEGINI FASQLHAHLT GRKLFTSQYR SGVRIGDVNR DEHYSPHWQH 420
  421 LQQLRPVVKV MPGDTLVTTC VYDTRKRSKV TFGGYRIVDE MCVNYIYYYP ASDVEVCKSA 480
  481 ISNSTLRAYF SERHGMDGKR MQISDMYSNV KDWGNGVDEE FYNVLNVGNM NMNCLKSNGE 540
  541 PFEFESKDSR QSWENMARPT FVSGSFITTR DRFQCPAIND MINFE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] FFAS03 2.2 Cytochrome domain of cellobiose dehydrogenase
    2 View Details [167..500] PSI-BLAST 101.0 Reduced (Cu+) peptidylglycine alpha-hydroxylating monooxygenase with bound peptide and dioxygen
    3 View Details [501..585] MSA 1.045994 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.47169830054759 bayes_pls_golite062009
  • monooxygenase activity
    		•  2.99739186264821 bayes_pls_golite062009
  • binding
    		•  1.77306386718124 bayes_pls_golite062009
  • protein binding
    		•  1.12780009486864 bayes_pls_golite062009
  • catalytic activity
    		•  1.02941336036162 bayes_pls_golite062009
  • peptidylglycine monooxygenase activity
    		•  0.935857805012855 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
    		•  0.935857805012855 bayes_pls_golite062009
  • peptidylamidoglycolate lyase activity
    		•  0.586168066875981 bayes_pls_golite062009
  • copper ion binding
    		•  0.20857314694941 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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