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View Structure Prediction Details

Protein: tbh-1
Organism: Caenorhabditis elegans
Length: 585 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tbh-1.

Description E-value Query
Range
Subject
Range
gi|110665642 - gi|110665642|gb|ABG81467.1| dopamine beta-hydroxylase precursor [Bos taurus]
668.0 [0..1] [578..11]

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Predicted Domain #1
Region A:
Residues: [1-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSAVALLFL LVAYCGGVVH AGEIVAELYH TNVTVKWHTD YERQLVDFSI WFGASTPDVL  60
   61 FLGFSDFGDT NNSDVLMYYN SKKEIKDAYT NRDFKITSDL QQDFQLLRKR KDHIVVRRKL 120
  121 TTCDSRDYAF LPGTTQFYIA ASWGSTNLVD IRDKRWVVDK KFGKVI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.2
Match: 1d7cA
Description: Cytochrome domain of cellobiose dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [167-500]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGPTDQPNIE EEPAALEKDV KVVIVNSNSP DPIPNVETTY KCIIRKMPFD TVNNMYHVVR  60
   61 MEPYVTPGNE HLVHHMEIFM CRDEVEEWSG SCNDPKKPPK SKSCSHVIAA WAMGEGPIHY 120
  121 PKEAGLPIGG KGKNAYVMVE IHYNNPELHK GVIDSSGFQF FVTGQLRKYD AGIMELGLIY 180
  181 SDANSVPPNQ KAWAMNGYCP SQCTKNLPEE GINIFASQLH AHLTGRKLFT SQYRSGVRIG 240
  241 DVNRDEHYSP HWQHLQQLRP VVKVMPGDTL VTTCVYDTRK RSKVTFGGYR IVDEMCVNYI 300
  301 YYYPASDVEV CKSAISNSTL RAYFSERHGM DGKR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 101.0
Match: 1sdwA
Description: Reduced (Cu+) peptidylglycine alpha-hydroxylating monooxygenase with bound peptide and dioxygen
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3.47169830054759 bayes_pls_golite062009
monooxygenase activity 2.99739186264821 bayes_pls_golite062009
binding 1.77306386718124 bayes_pls_golite062009
protein binding 1.12780009486864 bayes_pls_golite062009
catalytic activity 1.02941336036162 bayes_pls_golite062009
peptidylglycine monooxygenase activity 0.935857805012855 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen 0.935857805012855 bayes_pls_golite062009
peptidylamidoglycolate lyase activity 0.586168066875981 bayes_pls_golite062009
copper ion binding 0.20857314694941 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [501-585]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQISDMYSNV KDWGNGVDEE FYNVLNVGNM NMNCLKSNGE PFEFESKDSR QSWENMARPT  60
   61 FVSGSFITTR DRFQCPAIND MINFE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle