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Protein Overview: chn-1

General Information:
Name(s) found: chn-1 / CE29991 [WormBase]
Description(s) found:
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  • WBGene00000500 locus:chn-1 status:Confirmed UniProt:G5ECY6 protein_id:CCD71994.1 [WormBase]
  • gi|25141381|ref|NP_491781.2| C-term of Hsp70-iNteracting protein (CHIP family) family member (chn-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|16950456|gb|AAB53012.2| C-term of hsp70-interacting protein (chip family) protein 1 [Caenorhabditis elegans] [NCBI NR]
  • gi|12276029|gb|AAG50227.1|AF303269_1 Hsp70-interacting protein [Caenorhabditis elegans] [NCBI NR]
  • [wormpep79.fasta]
  • CE29991 WBGene00000500 locus:chn-1 status:Confirmed TR:Q9BMU2 protein_id:AAB53012.2 [wormpep150.fasta]
  • 29991 WBGene00000500 locus:chn-1 status:Confirmed TR:Q9BMU2 protein_id:AAB53012.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • c-term of Hsp70-iNteracting protein, CHIP family, TPR domains containing protein, related to hsp70/hsp90 organizing protein (31.1 kD) (chn-1) [Caenorhabditis elegans]gi|16950456|gb|AAB53012.2| C-term of hsp70-interacting protein (chip family) protein 1 [ [nrdb_11152004_Chlamydomonas]
  • locus:chn-1 status:Confirmed TR:Q9BMU2 protein_id:AAB53012.2 [wormpep115.fasta.reversed]
  • CE29991 status:Confirmed TR:Q9BMU2 protein_id:AAB53012.2 [wormpep80.hongbin]
  • CE29991 WBGene00000500 locus:chn-1 status:Confirmed UniProt:Q9BMU2_CAEEL protein_id:AAB53012.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE29991 WBGene00000500 locus:chn-1 status:Confirmed UniProt:Q9BMU2_CAEEL protein_id:AAB53012.2| [wormORF-contam.fasta]
  • C-term of hsp70-interacting protein (chip family) protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • C-term of Hsp70-iNteracting protein (CHIP family) family member (chn-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hsp70-interacting protein [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE29991 WBGene00000500 locus:chn-1 status:Confirmed UniProt:Q9BMU2 protein_id:AAB53012.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE29991 WBGene00000500 locus:chn-1 status:Confirmed UniProt:G5ECY6 protein_id:CCD71994.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • C-term of Hsp70-iNteracting protein (CHIP family) OS=Caenorhabditis elegans GN=chn-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 266 amino acids

    Gene Ontology:
    Cellular Component: ubiquitin ligase complex [IEALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: locomotion [IGILink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    protein polyubiquitination [IDALink to PubMed article]
    sarcomere organization [IGILink to PubMed article]
    oviposition [IGILink to PubMed article]
    protein autoubiquitination [IDALink to PubMed article]
    protein ubiquitination [IDALink to PubMed article][IEALink to PubMed article]
    Molecular Function: ubiquitin-protein ligase activity [IDALink to PubMed article][IEALink to PubMed article]
    ubiquitin protein ligase binding [IPILink to PubMed article]
    chaperone binding [IPILink to PubMed article]
    Hsp70 protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGAEQHNT NGKKCYMNKR YDDAVDHYSK AIKVNPLPKY YQNRAMCYFQ LNNLKMTEED  60
   61 CKRALELSPN EVKPLYFLGN VFLQSKKYSE AISCLSKALY HNAVITNAPD IENALKRARH 120
  121 QKYEEEESKR IVQDVEFHTY LESLIEKDRQ ENSENPEELQ RADMAKKRLT ELTLATQEKR 180
  181 QNREVPEMLC GKITLELMKE PVIVPSGITY DREEIVQHLR RIGHFDPVTR KPLTENEIIP 240
  241 NYALKEVIEK FLDDNPWAKY EPGGMV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..266] PSI-BLAST 30.522879 Crystal structure of the CHIP U-box E3 ubiquitin ligase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  5.97121728620188 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.78935175140238 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.75377804653841 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  3.82459130917693 bayes_pls_golite062009
  • protein binding
    		•  2.64803540957326 bayes_pls_golite062009
  • binding
    		•  2.14721962003828 bayes_pls_golite062009
  • SMAD binding
    		•  1.93335489484338 bayes_pls_golite062009
  • ubiquitin-ubiquitin ligase activity
    		•  1.37401357060257 bayes_pls_golite062009
  • heat shock protein binding
    		•  1.23450221149054 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.15544062259083 bayes_pls_golite062009
  • unfolded protein binding
    		•  1.03065657981002 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.952465452241625 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  0.637551805535732 bayes_pls_golite062009
  • ligase activity
    		•  0.63517530468004 bayes_pls_golite062009
  • DNA binding
    		•  0.618808911370101 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.549461161056205 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52386813728704 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.212156557156054 bayes_pls_golite062009
  • peptidase activity
    		•  0.184055035984234 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.159023519781458 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • transcription factor binding
    		•  0.12026866735209 bayes_pls_golite062009
  • transcription activator activity
    		•  0.031505858565037 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle