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Protein Overview: CE30299

General Information:
Name(s) found: CE30299 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00020347 status:Partially_confirmed UniProt:Q8T8N8 protein_id:CCD67612.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 697 amino acids

    Gene Ontology:
    Cellular Component: fatty acid beta-oxidation multienzyme complex [IEALink to PubMed article]
    mitochondrion [IEALink to PubMed article]
    Biological Process: fatty acid catabolic process [IEALink to PubMed article]
    fatty acid beta-oxidation [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    metabolic process [IEALink to PubMed article]
    valine metabolic process [IEALink to PubMed article]
    menaquinone biosynthetic process [IEALink to PubMed article]
    fatty acid metabolic process [IEALink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: naphthoate synthase activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]
    3-hydroxyacyl-CoA dehydrogenase activity [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    3-hydroxybutyryl-CoA epimerase activity [IEALink to PubMed article]
    3-hydroxyisobutyrate dehydrogenase activity [IEALink to PubMed article]
    dodecenoyl-CoA delta-isomerase activity [IEALink to PubMed article]
    enoyl-CoA hydratase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFFHDVHGRF HREARQWALL RFHQKEMLSR LVHQSSSTLR TNLSFRLFSQ SAPAMQTTHR  60
   61 VEKQGDVAVV KIDLPNTKEN VLNKALFAEM KATLDKLQSD ESIKSIVVMS GKPNSFVAGA 120
  121 DIQMIKAEGT ATATETLSRE GQEQFFRIEK SQKPVVAAIM GSCMGGGLEL ALACHYRIAV 180
  181 NDKKTLLSLP EVMLGLLPGA GGTQRLPKLT TVQNVLDLTL TGKKIKADKA KKIGIVDRVI 240
  241 QPLGDGLGPA AENTHKYLEE IAVKAAQELA NGKLKINRDK GFMHKATQAV MTNSLFLDNV 300
  301 VLKMAKDKLM KLTAGNYPAP LKILDVVRTA YVDPKKGFEA EAKAFGELSQ TFQSKALIGL 360
  361 FDGSTDAKKN KYGKGLPVNE IAVVGAGLMG AGIANVTIDK GIRTVLLDAN PAGVERGQNQ 420
  421 IATHLNKQVK RRKINKLEKE RIYNHLVPTI DYSAMKNADV VIEAVFEDLQ LKHKVIKQIE 480
  481 SVVGPNTIIA SNTSALPIKD IAAASSRPDK VIGMHYFSPV EKMQLLEIIT HDGTSKETLA 540
  541 TAAQLGLKQG KLVVVVKDCP GFFVVRCLGP MTAEIMRLLQ EGVDPAELDK LTTKFGFPVG 600
  601 AATLADEVGL DVAEHVAQFL GKALGPRLGG GSADLLSELV KAGHKGRKTG KGIFVYGDGK 660
  661 KGSKKVNDEA TKLLQKYKLT PNASVRPSNP SCLSFRQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..697] PSI-BLAST 157.0 fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3-hydroxybutyryl-CoA epimerase activity
    		•  6.21347266913168 bayes_pls_golite062009
  • long-chain-3-hydroxyacyl-CoA dehydrogenase activity
    		•  5.99914207874933 bayes_pls_golite062009
  • racemase and epimerase activity, acting on hydroxy acids and derivatives
    		•  5.93014177440654 bayes_pls_golite062009
  • long-chain-enoyl-CoA hydratase activity
    		•  5.38361434383109 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydratase activity
    		•  4.29069790566708 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  4.25084649365698 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  3.92947460544831 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  3.89913842968597 bayes_pls_golite062009
  • acetyl-CoA carboxylase activity
    		•  3.85567083340773 bayes_pls_golite062009
  • acetyl-CoA C-acyltransferase activity
    		•  3.6090947563188 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  3.4980371783229 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  3.02758902218302 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing C=C bonds
    		•  1.97586838275054 bayes_pls_golite062009
  • dodecenoyl-CoA delta-isomerase activity
    		•  1.80820904754223 bayes_pls_golite062009
  • catalytic activity
    		•  1.46154163027498 bayes_pls_golite062009
  • propionyl-CoA carboxylase activity
    		•  1.20853698666984 bayes_pls_golite062009
  • phosphogluconate dehydrogenase (decarboxylating) activity
    		•  1.10855899772836 bayes_pls_golite062009
  • ligase activity
    		•  0.98581896521131 bayes_pls_golite062009
  • transporter activity
    		•  0.793769336118517 bayes_pls_golite062009
  • binding
    		•  0.776704702114336 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.635891484075352 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  0.530688665000667 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.300373102236296 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.239024094835991 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.201915860594054 bayes_pls_golite062009
  • signal transducer activity
    		•  0.201915860594054 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.165260811069909 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  0.0962368786590111 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.0257250793986203 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle