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Protein Overview: csp-1

General Information:
Name(s) found: csp-1 / CE29378 [WormBase]
Description(s) found:
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  • WBGene00000819 locus:csp-1 status:Confirmed UniProt:G5EBM1 protein_id:CAB07698.2 [WormBase]
  • gi|71998301|ref|NP_001022452.1| CaSPase family member (csp-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|4063368|gb|AAC98292.1| caspase-related protein 1A [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_496857.1| caspase (61.5 kD) (csp-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|15718317|emb|CAB07698.2| C. elegans protein Y48E1B.13a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • pir||T43633 caspase-related proteinase 1A (EC 3.4.22.-) - Caenorhabditis elegans [NCBI NR]
  • [wormpep67.fasta]
  • CE29378 WBGene00000819 locus:csp-1 C14 peptidase status:Confirmed TR:O18203 protein_id:CAB07698.2 [wormpep150.fasta]
  • 29378 WBGene00000819 locus:csp-1 C14 peptidase status:Partially_confirmed TR:O18203 protein_id:CAB07698.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • caspase (61.5 kD) (csp-1) [Caenorhabditis elegans]gi|15718317|emb|CAB07698.2| Hypothetical protein Y48E1B.13a [Caenorhabditis elegans]gi|4063368|gb|AAC98292.1| caspase-related protein 1A [Caenorhabditis elegans]gi|11359738|pir||T43633 caspase-related p [nrdb_11152004_Chlamydomonas]
  • CE29378 WBGene00000819 locus:csp-1 C14 peptidase status:Partially_confirmed TR:O18203 protein_id:CAB07698.2 [wormpep132.fasta]
  • 29378 WBGene00000819 locus:csp-1 C14 peptidase status:Confirmed TR:O18203 protein_id:CAB07698.2 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:csp-1 C14 peptidase status:Partially_confirmed TR:O18203 protein_id:CAB07698.2 [wormpep115.fasta.reversed]
  • CE29378 C14 peptidase status:Partially_confirmed TR:O18203 protein_id:CAB07698.2 [wormpep80.hongbin]
  • CE29378 WBGene00000819 locus:csp-1 C14 peptidase status:Confirmed UniProt:O18203_CAEEL protein_id:CAB07698.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE29378 WBGene00000819 locus:csp-1 C14 peptidase status:Confirmed UniProt:O18203_CAEEL protein_id:CAB07698.2| [wormORF-contam.fasta]
  • caspase-related protein 1A [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein Y48E1B.13a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CaSPase family member (csp-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE29378 WBGene00000819 locus:csp-1 C14 peptidase status:Confirmed UniProt:O18203 protein_id:CAB07698.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE29378 WBGene00000819 locus:csp-1 C14 peptidase status:Confirmed UniProt:G5EBM1 protein_id:CAB07698.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE29378 WBGene00000819 locus:csp-1 status:Confirmed UniProt:G5EBM1 protein_id:CAB07698.2 [wormpep246-ecoli-contam.fasta]
  • CaSPase OS=Caenorhabditis elegans GN=csp-1 PE=2 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 536 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEALink to PubMed article]
    apoptosis [IEALink to PubMed article]
    Molecular Function: caspase activity [IEALink to PubMed article]
    cysteine-type peptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLKTIEDNC KSQFDDDLVE DFNNFQTTSS MSSSTTISTE DFNTIEIEST FEICRSGSYT  60
   61 EEPILGENDE FLIDFEMERF LKFLKDKTKQ VEKRKEPFSQ KEIYAVFQRR IKSELCIETV 120
  121 KKKFQPLLPN AIQTCEFDEE TMIRMIYGAG IRIDSVDFWN RFTSKATISL DCYSRLISYS 180
  181 SDSLTLSGTH RSGFTYHWIS TPPVTYHRTE NKDPNIQEPS PVEFLDVQSS LGSSMKPPIL 240
  241 DKPTKLDDPA ETRHDCSYSL EEYDSQSRMP RTDAKKSNHK HKYCYEMNSN PRGTVLILSN 300
  301 ENFKNMERRV GTKQDEVNLT KLFQKLQYTV ICKRNLEAES MLEAIKEFAE MAHTDSIILF 360
  361 LLSHGDGAGS VFGIDDMPVN VMEVSTYLAY HQNLLLKPKW VAVSACRGGK LNMGVPVDGL 420
  421 PALEDKCAPI SKFWNLMMSR IMPGTFTSLN ADVIISFSTT DGFTSYRDEE AGTWYIKSMC 480
  481 KVFNKHSKTM HLLDILTETG RNVVTKYENV QGNVVLKQAP EILSRLTKQW HFSRSM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..221] Pfam 33.356547 No description for PF04435.9 was found. No confident structure predictions are available.
    2 View Details [222..536] PSI-BLAST 61.0 Caspase-7

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  3.24815349282067 bayes_pls_golite062009
  • protein binding
    		•  2.96725373477762 bayes_pls_golite062009
  • binding
    		•  2.91261616137775 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  2.60103365510479 bayes_pls_golite062009
  • hydrolase activity
    		•  2.51110071893544 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  2.37850336421322 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.07426831021634 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.82979469421101 bayes_pls_golite062009
  • endopeptidase activity
    		•  1.58137850574981 bayes_pls_golite062009
  • cyclin-dependent protein kinase inhibitor activity
    		•  1.38256499817012 bayes_pls_golite062009
  • catalytic activity
    		•  1.03907950272772 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.0737251792690711 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle