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View Structure Prediction Details

Protein: csp-1
Organism: Caenorhabditis elegans
Length: 536 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for csp-1.

Description E-value Query
Range
Subject
Range
gi|119590655, gi... - gi|62988904|gb|AAY24291.1| unknown [Homo sapiens], gi|47078272|ref|NP_116759.2| caspase 10 isoform d...
301.0 [0..32] [533..20]

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Predicted Domain #1
Region A:
Residues: [1-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLKTIEDNC KSQFDDDLVE DFNNFQTTSS MSSSTTISTE DFNTIEIEST FEICRSGSYT  60
   61 EEPILGENDE FLIDFEMERF LKFLKDKTKQ VEKRKEPFSQ KEIYAVFQRR IKSELCIETV 120
  121 KKKFQPLLPN AIQTCEFDEE TMIRMIYGAG IRIDSVDFWN RFTSKATISL DCYSRLISYS 180
  181 SDSLTLSGTH RSGFTYHWIS TPPVTYHRTE NKDPNIQEPS P

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 33.356547
Match: PF04435.9
Description: No description for PF04435.9 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [222-536]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEFLDVQSSL GSSMKPPILD KPTKLDDPAE TRHDCSYSLE EYDSQSRMPR TDAKKSNHKH  60
   61 KYCYEMNSNP RGTVLILSNE NFKNMERRVG TKQDEVNLTK LFQKLQYTVI CKRNLEAESM 120
  121 LEAIKEFAEM AHTDSIILFL LSHGDGAGSV FGIDDMPVNV MEVSTYLAYH QNLLLKPKWV 180
  181 AVSACRGGKL NMGVPVDGLP ALEDKCAPIS KFWNLMMSRI MPGTFTSLNA DVIISFSTTD 240
  241 GFTSYRDEEA GTWYIKSMCK VFNKHSKTMH LLDILTETGR NVVTKYENVQ GNVVLKQAPE 300
  301 ILSRLTKQWH FSRSM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.0
Match: 1kmcA
Description: Caspase-7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.24815349282067 bayes_pls_golite062009
protein binding 2.96725373477762 bayes_pls_golite062009
binding 2.91261616137775 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 2.60103365510479 bayes_pls_golite062009
hydrolase activity 2.51110071893544 bayes_pls_golite062009
cysteine-type peptidase activity 2.37850336421322 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.07426831021634 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.82979469421101 bayes_pls_golite062009
endopeptidase activity 1.58137850574981 bayes_pls_golite062009
cyclin-dependent protein kinase inhibitor activity 1.38256499817012 bayes_pls_golite062009
catalytic activity 1.03907950272772 bayes_pls_golite062009
enzyme regulator activity 0.0737251792690711 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle