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Protein Overview: CE26950

General Information:
Name(s) found: CE26950 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00020347 status:Confirmed UniProt:Q9BIC3 protein_id:CCD67611.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 755 amino acids

    Gene Ontology:
    Cellular Component: fatty acid beta-oxidation multienzyme complex [IEALink to PubMed article]
    mitochondrion [IEALink to PubMed article]
    Biological Process: fatty acid catabolic process [IEALink to PubMed article]
    fatty acid beta-oxidation [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    metabolic process [IEALink to PubMed article]
    valine metabolic process [IEALink to PubMed article]
    menaquinone biosynthetic process [IEALink to PubMed article]
    fatty acid metabolic process [IEALink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: naphthoate synthase activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]
    3-hydroxyacyl-CoA dehydrogenase activity [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    3-hydroxybutyryl-CoA epimerase activity [IEALink to PubMed article]
    3-hydroxyisobutyrate dehydrogenase activity [IEALink to PubMed article]
    dodecenoyl-CoA delta-isomerase activity [IEALink to PubMed article]
    enoyl-CoA hydratase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRLVHQSS STLRTNLSFR LFSQSAPAMQ TTHRVEKQGD VAVVKIDLPN TKENVLNKAL  60
   61 FAEMKATLDK LQSDESIKSI VVMSGKPNSF VAGADIQMIK AEGTATATET LSREGQEQFF 120
  121 RIEKSQKPVV AAIMGSCMGG GLELALACHY RIAVNDKKTL LSLPEVMLGL LPGAGGTQRL 180
  181 PKLTTVQNVL DLTLTGKKIK ADKAKKIGIV DRVIQPLGDG LGPAAENTHK YLEEIAVKAA 240
  241 QELANGKLKI NRDKGFMHKA TQAVMTNSLF LDNVVLKMAK DKLMKLTAGN YPAPLKILDV 300
  301 VRTAYVDPKK GFEAEAKAFG ELSQTFQSKA LIGLFDGSTD AKKNKYGKGL PVNEIAVVGA 360
  361 GLMGAGIANV TIDKGIRTVL LDANPAGVER GQNQIATHLN KQVKRRKINK LEKERIYNHL 420
  421 VPTIDYSAMK NADVVIEAVF EDLQLKHKVI KQIESVVGPN TIIASNTSAL PIKDIAAASS 480
  481 RPDKVIGMHY FSPVEKMQLL EIITHDGTSK ETLATAAQLG LKQGKLVVVV KDCPGFFVVR 540
  541 CLGPMTAEIM RLLQEGVDPA ELDKLTTKFG FPVGAATLAD EVGLDVAEHV AQFLGKALGP 600
  601 RLGGGSADLL SELVKAGHKG RKTGKGIFVY GDGKKGSKKV NDEATKLLQK YKLTPNASVS 660
  661 SPEDRQIRLV SRFVNEALLC LEEGVLASPS DGDIASVFGV GFPPFWGGPF RFVDLYGADK 720
  721 LVKSMEKFAG AYEAVQFEPC QLLKDHAKSG KKFYN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..755] PSI-BLAST 177.0 fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • long-chain-3-hydroxyacyl-CoA dehydrogenase activity
    		•  4.80462645980977 bayes_pls_golite062009
  • 3-hydroxybutyryl-CoA epimerase activity
    		•  4.30714786835318 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydratase activity
    		•  4.29069790566708 bayes_pls_golite062009
  • long-chain-enoyl-CoA hydratase activity
    		•  4.09442487131529 bayes_pls_golite062009
  • racemase and epimerase activity, acting on hydroxy acids and derivatives
    		•  4.03462681763369 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  3.89913842968597 bayes_pls_golite062009
  • acetyl-CoA carboxylase activity
    		•  3.85567083340773 bayes_pls_golite062009
  • acetyl-CoA C-acyltransferase activity
    		•  3.6090947563188 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  3.4980371783229 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  3.06391460989761 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  3.02758902218302 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • propionyl-CoA carboxylase activity
    		•  1.20853698666984 bayes_pls_golite062009
  • phosphogluconate dehydrogenase (decarboxylating) activity
    		•  1.10855899772836 bayes_pls_golite062009
  • transporter activity
    		•  0.793769336118517 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.788034697021177 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.635891484075352 bayes_pls_golite062009
  • binding
    		•  0.553666136934364 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  0.530688665000667 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  0.439912268968251 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.300373102236296 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.239024094835991 bayes_pls_golite062009
  • signal transducer activity
    		•  0.201915860594054 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.201915860594054 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.165260811069909 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  0.0962368786590111 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.0257250793986203 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.66

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle