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Protein Overview: csn-1

General Information:
Name(s) found: csn-1 / CE26200 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00000813 locus:csn-1 COP9 signalosome complex subunit 1 status:Confirmed UniProt:Q9GS00 protein_id:CAC14399.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 601 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic cleavage [IMPLink to PubMed articleLink to PubMed article]
    establishment of mitotic spindle orientation [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    cytokinesis [IMPLink to PubMed articleLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNELLDDPM DTGAPAAEAA AADEPLPPAH GIDREVTPKP AGNPDLMQQS LDNPAIPMHL  60
   61 IEKRDDRRES CDDGYSLTVN ESAIDIESLA CSYDSNAFFL RARFIARHCP ILRADAYISL 120
  121 INYLKEHTTD ITHYVAFFNE LESELARKEF KNRQLNFQIP LRDQKWIEEN GATWQSTTDQ 180
  181 LQAEYKRHKD EGVKESTRRA MEDLFQHYMM AGKIDEAIRL YSRGIRDYCT QLKHSINMWI 240
  241 NWMEVAICAN DWGKLDTVTN TAYRSLKDAD DAEKNSQQSQ QAPPQRGENA PYMVERDPNA 300
  301 PIQTLTNRQL IETALAKCLA AQVLLKLRNK RYSQVVETIL QIKTECLQSK WFVTSSDLGI 360
  361 YGMLSAMATM SRADLKLQVS GNGTFRKLLE SEPQLIELLG SYTSSRFGRC FEIMRSVKPR 420
  421 LLLDPFISRN VDELFEKIRQ KCVLQYLQPY STIKMATMAE AVGMSSAELQ LSLLELIEQK 480
  481 HVSLKIDQNE GIVRILDERD ENAILKRVNV TCDRATQKAK SLLWKTTLAG ANIHSISDKE 540
  541 TRPKRKNQKE SAKFDRNFGG IDVDEDPRGI AGPSGLSDDF NIAYDQQPQQ QVQYLEDLGD 600
  601 I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..80] deduced N/A No confident structure predictions are available.
    2 View Details [81..184] MSA 4.393997 View MSA. No confident structure predictions are available.
    3 View Details [185..353] PSI-BLAST 4.154902 Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
    4 View Details [354..446] deduced N/A No confident structure predictions are available.
    5 View Details [447..538] PSI-BLAST 9.0 Solution structure of the PCI domain
    6 View Details [539..601] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • transcription regulator activity
    		•  5.29569167054278 bayes_pls_golite062009
  • DNA binding
    		•  4.90756541371868 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.69183445184264 bayes_pls_golite062009
  • transcription factor activity
    		•  4.14166958134441 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.48053910222825 bayes_pls_golite062009
  • transcription activator activity
    		•  2.29614125067822 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.19033875364989 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.48055533524841 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.33374581364046 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.27763700765562 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.12147035668008 bayes_pls_golite062009
  • transcription factor binding
    		•  0.83705247708153 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.754042916649094 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.657984195080457 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.486434906547244 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.286130392009263 bayes_pls_golite062009
  • hydrolase activity
    		•  0.140191206949582 bayes_pls_golite062009
  • transferase activity
    		•  0.064832527337659 bayes_pls_golite062009
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle